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Volumn 208, Issue 1-2, 2009, Pages 19-29

Autoimmune spread to myelin is associated with experimental autoimmune encephalomyelitis induced by a neuronal protein, β-Synuclein

Author keywords

Antigens peptides epitopes; Autoantibodies; Autoimmunity; Rodent; T cells

Indexed keywords

AMINO ACID; BETA SYNUCLEIN; BRAIN ANTIGEN; ENCEPHALITOGENIC PROTEIN; EPITOPE; MYELIN; MYELIN ENCEPHALITOGEN; UNCLASSIFIED DRUG;

EID: 62549105276     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.12.009     Document Type: Article
Times cited : (8)

References (52)
  • 1
    • 3242804567 scopus 로고    scopus 로고
    • Cellular mechanisms governing cross-presentation of exogenous antigens
    • Ackerman A.L., and Cresswell P. Cellular mechanisms governing cross-presentation of exogenous antigens. Nat. Immunol. 5 (2004) 678-684
    • (2004) Nat. Immunol. , vol.5 , pp. 678-684
    • Ackerman, A.L.1    Cresswell, P.2
  • 3
    • 0020658978 scopus 로고
    • Detection of autoimmune cells proliferating to myelin basic protein and selection of T cell lines that mediate experimental autoimmune encephalomyelitis (EAE) in mice
    • Ben-Nun A., and Lando Z. Detection of autoimmune cells proliferating to myelin basic protein and selection of T cell lines that mediate experimental autoimmune encephalomyelitis (EAE) in mice. J. Immunol. 130 (1983) 1205-1209
    • (1983) J. Immunol. , vol.130 , pp. 1205-1209
    • Ben-Nun, A.1    Lando, Z.2
  • 4
    • 32944455545 scopus 로고    scopus 로고
    • Anatomy of T cell autoimmunity to myelin oligodendrocyte glycoprotein (MOG): prime role of MOG44F in selection and control of MOG-reactive T cells in H-2b mice
    • Ben-Nun A., Kerlero de Rosbo N., Kaushansky N., Eisenstein M., Cohen L., Kaye J.F., and Mendel I. Anatomy of T cell autoimmunity to myelin oligodendrocyte glycoprotein (MOG): prime role of MOG44F in selection and control of MOG-reactive T cells in H-2b mice. Eur. J. Immunol. 36 (2006) 478-493
    • (2006) Eur. J. Immunol. , vol.36 , pp. 478-493
    • Ben-Nun, A.1    Kerlero de Rosbo, N.2    Kaushansky, N.3    Eisenstein, M.4    Cohen, L.5    Kaye, J.F.6    Mendel, I.7
  • 5
    • 0034992601 scopus 로고    scopus 로고
    • Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences
    • Bjartmar C., and Trapp B.D. Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences. Curr. Opin. Neurol. 14 (2001) 271-278
    • (2001) Curr. Opin. Neurol. , vol.14 , pp. 271-278
    • Bjartmar, C.1    Trapp, B.D.2
  • 6
    • 0642345898 scopus 로고    scopus 로고
    • Axonal degeneration and progressive neurologic disability in multiple sclerosis
    • Bjartmar C., and Trapp B.D. Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox. Res. 5 (2003) 157-164
    • (2003) Neurotox. Res. , vol.5 , pp. 157-164
    • Bjartmar, C.1    Trapp, B.D.2
  • 7
    • 0033663894 scopus 로고    scopus 로고
    • Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients
    • Bjartmar C., Kidd G., Mork S., Rudick R., and Trapp B.D. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann. Neurol. 48 (2000) 893-901
    • (2000) Ann. Neurol. , vol.48 , pp. 893-901
    • Bjartmar, C.1    Kidd, G.2    Mork, S.3    Rudick, R.4    Trapp, B.D.5
  • 8
    • 0037441487 scopus 로고    scopus 로고
    • Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease
    • Bjartmar C., Wujek J.R., and Trapp B.D. Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease. J. Neurol. Sci. 206 (2003) 165-171
    • (2003) J. Neurol. Sci. , vol.206 , pp. 165-171
    • Bjartmar, C.1    Wujek, J.R.2    Trapp, B.D.3
  • 9
    • 0023879477 scopus 로고
    • Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase
    • Chang Y.C., and Gottlieb D.I. Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase. J. Neurosci. 8 (1988) 2123-2130
    • (1988) J. Neurosci. , vol.8 , pp. 2123-2130
    • Chang, Y.C.1    Gottlieb, D.I.2
  • 10
    • 0000361150 scopus 로고
    • Histologie de la sclerose en plaques
    • Charcot J. Histologie de la sclerose en plaques. Gaz. Hôp., Paris 41 (1868) 554-555
    • (1868) Gaz. Hôp., Paris , vol.41 , pp. 554-555
    • Charcot, J.1
  • 12
    • 0025858593 scopus 로고
    • Amyloid precursor protein and ubiquitin immunoreactivity in dystrophic axons is not unique to Alzheimer's disease
    • Cochran E., Bacci B., Chen Y., Patton A., Gambetti P., and Autilio-Gambetti L. Amyloid precursor protein and ubiquitin immunoreactivity in dystrophic axons is not unique to Alzheimer's disease. Am. J. Pathol. 139 (1991) 485-489
    • (1991) Am. J. Pathol. , vol.139 , pp. 485-489
    • Cochran, E.1    Bacci, B.2    Chen, Y.3    Patton, A.4    Gambetti, P.5    Autilio-Gambetti, L.6
  • 14
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B., Matyszak M.K., Esiri M.M., and Perry V.H. Axonal damage in acute multiple sclerosis lesions. Brain 120 (1997) 393-399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 16
    • 0030450005 scopus 로고    scopus 로고
    • The spectrum of traumatic axonal injury
    • Gennarelli T.A. The spectrum of traumatic axonal injury. Neuropathol. Appl. Neurobiol. 22 (1996) 509-513
    • (1996) Neuropathol. Appl. Neurobiol. , vol.22 , pp. 509-513
    • Gennarelli, T.A.1
  • 19
    • 0032543235 scopus 로고    scopus 로고
    • Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens
    • Heath W.R., Kurts C., Miller J.F., and Carbone F.R. Cross-tolerance: a pathway for inducing tolerance to peripheral tissue antigens. J. Exp. Med. 187 (1998) 1549-1553
    • (1998) J. Exp. Med. , vol.187 , pp. 1549-1553
    • Heath, W.R.1    Kurts, C.2    Miller, J.F.3    Carbone, F.R.4
  • 23
    • 0029128438 scopus 로고
    • Spreading of the immune response to different myelin basic protein peptides in chronic experimental autoimmune encephalomyelitis in B10.RIII mice
    • Jansson L., Diener P., Engstrom A., Olsson T., and Holmdahl R. Spreading of the immune response to different myelin basic protein peptides in chronic experimental autoimmune encephalomyelitis in B10.RIII mice. Eur. J. Immunol. 25 (1995) 2195-2200
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2195-2200
    • Jansson, L.1    Diener, P.2    Engstrom, A.3    Olsson, T.4    Holmdahl, R.5
  • 24
    • 4043144986 scopus 로고    scopus 로고
    • Initiation of immune responses in brain is promoted by local dendritic cells
    • Karman J., Ling C., Sandor M., and Fabry Z. Initiation of immune responses in brain is promoted by local dendritic cells. J. Immunol. 173 (2004) 2353-2361
    • (2004) J. Immunol. , vol.173 , pp. 2353-2361
    • Karman, J.1    Ling, C.2    Sandor, M.3    Fabry, Z.4
  • 25
    • 33750836408 scopus 로고    scopus 로고
    • Epitope specificity of autoreactive T and B cells associated with experimental autoimmune encephalomyelitis and optic neuritis induced by oligodendrocyte-specific protein in SJL/J mice
    • Kaushansky N., Zhong M.C., Kerlero de Rosbo N., Hoeftberger R., Lassmann H., and Ben-Nun A. Epitope specificity of autoreactive T and B cells associated with experimental autoimmune encephalomyelitis and optic neuritis induced by oligodendrocyte-specific protein in SJL/J mice. J. Immunol. 177 (2006) 7364-7376
    • (2006) J. Immunol. , vol.177 , pp. 7364-7376
    • Kaushansky, N.1    Zhong, M.C.2    Kerlero de Rosbo, N.3    Hoeftberger, R.4    Lassmann, H.5    Ben-Nun, A.6
  • 26
    • 0005966256 scopus 로고    scopus 로고
    • T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein
    • Kerlero de Rosbo N., and Ben-Nun A. T-cell responses to myelin antigens in multiple sclerosis; relevance of the predominant autoimmune reactivity to myelin oligodendrocyte glycoprotein. J. Autoimmun. 11 (1998) 287-299
    • (1998) J. Autoimmun. , vol.11 , pp. 287-299
    • Kerlero de Rosbo, N.1    Ben-Nun, A.2
  • 27
    • 3142781394 scopus 로고    scopus 로고
    • The myelin-associated oligodendrocytic basic protein region MOBP15-36 encompasses the immunodominant major encephalitogenic epitope(s) for SJL/J mice and predicted epitope(s) for multiple sclerosis-associated HLA-DRB1*1501
    • Kerlero de Rosbo N., Kaye J.F., Eisenstein M., Mendel I., Hoeftberger R., Lassmann H., Milo R., and Ben-Nun A. The myelin-associated oligodendrocytic basic protein region MOBP15-36 encompasses the immunodominant major encephalitogenic epitope(s) for SJL/J mice and predicted epitope(s) for multiple sclerosis-associated HLA-DRB1*1501. J. Immunol. 173 (2004) 1426-1435
    • (2004) J. Immunol. , vol.173 , pp. 1426-1435
    • Kerlero de Rosbo, N.1    Kaye, J.F.2    Eisenstein, M.3    Mendel, I.4    Hoeftberger, R.5    Lassmann, H.6    Milo, R.7    Ben-Nun, A.8
  • 29
    • 0026649994 scopus 로고
    • Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage
    • Kuchroo V.K., Sobel R.A., Laning J.C., Martin C.A., Greenfield E., Dorf M.E., and Lees M.B. Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. J. Immunol. 148 (1992) 3776-3782
    • (1992) J. Immunol. , vol.148 , pp. 3776-3782
    • Kuchroo, V.K.1    Sobel, R.A.2    Laning, J.C.3    Martin, C.A.4    Greenfield, E.5    Dorf, M.E.6    Lees, M.B.7
  • 30
    • 40749090813 scopus 로고    scopus 로고
    • Cross presentation of antigen on MHC class II via the draining lymph node after corneal transplantation in mice
    • Kuffova L., Netukova M., Duncan L., Porter A., Stockinger B., and Forrester J.V. Cross presentation of antigen on MHC class II via the draining lymph node after corneal transplantation in mice. J. Immunol. 180 (2008) 1353-1361
    • (2008) J. Immunol. , vol.180 , pp. 1353-1361
    • Kuffova, L.1    Netukova, M.2    Duncan, L.3    Porter, A.4    Stockinger, B.5    Forrester, J.V.6
  • 31
    • 0036788406 scopus 로고    scopus 로고
    • Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
    • Kuhlmann T., Lingfeld G., Bitsch A., Schuchardt J., and Bruck W. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 125 (2002) 2202-2212
    • (2002) Brain , vol.125 , pp. 2202-2212
    • Kuhlmann, T.1    Lingfeld, G.2    Bitsch, A.3    Schuchardt, J.4    Bruck, W.5
  • 32
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
    • Linington C., Bradl M., Lassmann H., Brunner C., and Vass K. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am. J. Pathol. 130 (1988) 443-454
    • (1988) Am. J. Pathol. , vol.130 , pp. 443-454
    • Linington, C.1    Bradl, M.2    Lassmann, H.3    Brunner, C.4    Vass, K.5
  • 33
    • 33646596928 scopus 로고    scopus 로고
    • Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
    • Liu Y., Teige I., Birnir B., and Issazadeh-Navikas S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat. Med. 12 (2006) 518-525
    • (2006) Nat. Med. , vol.12 , pp. 518-525
    • Liu, Y.1    Teige, I.2    Birnir, B.3    Issazadeh-Navikas, S.4
  • 37
    • 0029038922 scopus 로고
    • A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells
    • Mendel I., Kerlero de Rosbo N., and Ben-Nun A. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. Eur. J. Immunol. 25 (1995) 1951-1959
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1951-1959
    • Mendel, I.1    Kerlero de Rosbo, N.2    Ben-Nun, A.3
  • 38
    • 0037218641 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein
    • Mor F., Quintana F., Mimran A., and Cohen I.R. Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein. J. Immunol. 170 (2003) 628-634
    • (2003) J. Immunol. , vol.170 , pp. 628-634
    • Mor, F.1    Quintana, F.2    Mimran, A.3    Cohen, I.R.4
  • 40
    • 0032726280 scopus 로고    scopus 로고
    • Combined magnetization transfer and proton spectroscopic imaging in the assessment of pathologic brain lesions in multiple sclerosis
    • Pike G.B., de Stefano N., Narayanan S., Francis G.S., Antel J.P., and Arnold D.L. Combined magnetization transfer and proton spectroscopic imaging in the assessment of pathologic brain lesions in multiple sclerosis. AJNR. Am. J. Neuroradiol. 20 (1999) 829-837
    • (1999) AJNR. Am. J. Neuroradiol. , vol.20 , pp. 829-837
    • Pike, G.B.1    de Stefano, N.2    Narayanan, S.3    Francis, G.S.4    Antel, J.P.5    Arnold, D.L.6
  • 41
  • 42
    • 0037757575 scopus 로고    scopus 로고
    • Localization of alpha-, beta-, and gamma-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma
    • Quilty M.C., Gai W.P., Pountney D.L., West A.K., and Vickers J.C. Localization of alpha-, beta-, and gamma-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma. Exp. Neurol. 182 (2003) 195-207
    • (2003) Exp. Neurol. , vol.182 , pp. 195-207
    • Quilty, M.C.1    Gai, W.P.2    Pountney, D.L.3    West, A.K.4    Vickers, J.C.5
  • 43
    • 0026504022 scopus 로고
    • The identity of cells expressing MHC class II antigens in normal and pathological human brain
    • Sasaki A., and Nakazato Y. The identity of cells expressing MHC class II antigens in normal and pathological human brain. Neuropathol. Appl. Neurobiol. 18 (1992) 13-26
    • (1992) Neuropathol. Appl. Neurobiol. , vol.18 , pp. 13-26
    • Sasaki, A.1    Nakazato, Y.2
  • 46
    • 0037076504 scopus 로고    scopus 로고
    • Patients with progressive multiple sclerosis have elevated antibodies to neurofilament subunit
    • Silber E., Semra Y.K., Gregson N.A., and Sharief M.K. Patients with progressive multiple sclerosis have elevated antibodies to neurofilament subunit. Neurology 58 (2002) 1372-1381
    • (2002) Neurology , vol.58 , pp. 1372-1381
    • Silber, E.1    Semra, Y.K.2    Gregson, N.A.3    Sharief, M.K.4
  • 48
    • 11144297111 scopus 로고    scopus 로고
    • Biological markers in CSF and blood for axonal degeneration in multiple sclerosis
    • Teunissen C.E., Dijkstra C., and Polman C. Biological markers in CSF and blood for axonal degeneration in multiple sclerosis. Lancet. Neurol. 4 (2005) 32-41
    • (2005) Lancet. Neurol. , vol.4 , pp. 32-41
    • Teunissen, C.E.1    Dijkstra, C.2    Polman, C.3
  • 51
    • 0028070413 scopus 로고
    • Peptide determinants of myelin proteolipid protein (PLP) in autoimmune demyelinating disease: a review
    • Tuohy V.K. Peptide determinants of myelin proteolipid protein (PLP) in autoimmune demyelinating disease: a review. Neurochem. Res. 19 (1994) 935-944
    • (1994) Neurochem. Res. , vol.19 , pp. 935-944
    • Tuohy, V.K.1
  • 52
    • 0037442020 scopus 로고    scopus 로고
    • Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
    • Zhang G.X., Gran B., Yu S., Li J., Siglienti I., Chen X., Kamoun M., and Rostami A. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J. Immunol. 170 (2003) 2153-2160
    • (2003) J. Immunol. , vol.170 , pp. 2153-2160
    • Zhang, G.X.1    Gran, B.2    Yu, S.3    Li, J.4    Siglienti, I.5    Chen, X.6    Kamoun, M.7    Rostami, A.8


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