One-pot Van Leusen synthesis of 4,5-disubstituted oxazoles in ionic liquids

Synlett

Volumn , Issue 3, 2009, Pages 500-504

  Wu, Bo ^a   Wen, Jun ^a   Zhang, Ji ^a   Li, Jing ^a   Xiang, Yong Zhe ^a   Yu, Xiao Qi ^a  

^a China   (China)

Author keywords

Aldehydes; Halides; Ionic liquids; Tosylmethyl isocyanide; Van Leusen oxazole synthesis

Indexed keywords

EID: 62349129252     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0028-1087547     Document Type: Article

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30. 4, and concentrated in vacuum. The crude product was purified by chromatography on silica gel (PE-EtOAc, 4:1) to provide pure compound 2a (95%).
31. 4, and concentrated in vacuum. The crude product was purified by chromatography on silica gel (PE-EtOAc, 10:1) to provide pure compound 7a (85%).
32. 3)