Rapid and sensitive method for simultaneous determination of six carcinogenic aromatic amines in mainstream cigarette smoke by liquid chromatography/electrospray ionization tandem mass spectrometry

Journal of Chromatography A

Volumn 1216, Issue 15, 2009, Pages 3059-3063

  Saha, Subhrakanti ^a   Mistri, Rajib ^a   Ray, B C ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

2R4F; Aromatic amines; Cigarette smoke; LC MS MS

Indexed keywords

2R4F; ANALYTE; AROMATIC AMINES; CARCINOGENIC AROMATIC AMINES; CHROMATOGRAPHIC RETENTIONS; CIGARETTE SMOKE; FRAGMENTATION PATTERNS; INJECTION VOLUMES; ION PAIRS; LC/MS/MS; LIMIT OF DETECTIONS; MAINSTREAM CIGARETTE SMOKES; PEAK AREA RATIOS; PUBLIC HEALTH RISKS; REPRODUCIBILITY; SENSITIVE METHODS; SIMULTANEOUS DETERMINATIONS; TANDEM MASS SPECTROMETRIC; TANDEM MASS SPECTROMETRIES; TOBACCO SMOKES;

AMINATION; AROMATIC COMPOUNDS; AROMATIZATION; HEALTH RISKS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; RISK MANAGEMENT; SMOKE; TOBACCO;

AMINES;

1 NAPHTHYLAMINE; 2 METHYLANILINE; 2 NAPHTHYLAMINE; 4 BIPHENYLAMINE; ANILINE; AROMATIC AMINE; BENZIDINE; CARCINOGEN; CIGARETTE SMOKE;

ARTICLE; CHEMICAL ANALYSIS; CIGARETTE SMOKING; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

AIR POLLUTANTS; AMINES; BENZIDINES; CALIBRATION; CARCINOGENS, ENVIRONMENTAL; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TOBACCO SMOKE POLLUTION;

NICOTIANA TABACUM;

EID: 62249200496     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.01.069     Document Type: Article

References (21)

1. The Health Consequences of Smoking: A report of the Surgeon General, U.S. Department of Health and Human Services; Centers for Disease Control and Prevention, National Centre for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2004 [cited 2006, Dec. 5]. Available from: http://www.cdc.gov/tobacco/data_statistics/sgr/sgr_2004/index.htm.
2. Blot W.J., and Fraumeni Jr. J.F. In: Schotenfield D., and Fraumeni Jr. J. (Eds). Cancer Epidemiology and Prevention (1996), Oxford University Press, New York 637
3. Sasco A.J., Secretan M.B., and Straif K. Lung Cancer 45 (2004) S3
4. Baker R.R. In: Davis D.L., and Nielsen M.T. (Eds). Tobacco: Production, Chemistry, and Technology (1999), Blackwell, Oxford (Chapter 12)
5. Green C.R., and Rodgman A. Recent Adv. Tob. Sci. 22 (1996) 131
6. Borgerding M., and Klus H. Exp. Toxicol. Pathol. 57 (2005) 43
7. Hoffmann D., Hoffmann I., and El-Bayoumy K. Chem. Res. Toxicol. 14 (2001) 767
8. Masuda Y., and Hoffmann D. Anal. Chem. 41 (1969) 650
9. Hoffmann D., Masuda Y., and Wynder E.L. Nature 221 (1969) 254
10. Borgerding M.F., Bodnar J.A., Chung H.L., Mangan P.P., Mossison C.C., Risner C.H., Rogers J.C., Simmons D.F., Uhrig M.S., Wendelboe F.N., Wingate D.E., and Winkler L.S. Food Chem. Toxicol. 36 (1997) 169
11. Chen P.X., and Moldoveanu S.C. Beitr. Tabakforsch. Int. 20 (2003) 448
12. Stabbert R., Schafer K.H., Biefel C., and Rustemeier K. Rapid Commun. Mass Spectrom. 17 (2003) 2125
13. Pieraccini G., Luceri F., and Moneti G. Rapid Commun. Mass Spectrom. 6 (1992) 406
14. Forehand J.B., Dooly G.L., and Moldoveanu S.C. J. Chromatogr. A 898 (2000) 111
15. Smith C.J., Dooly G.L., and Moldoveanu S.C. J. Chromatogr. A 991 (2003) 99
16. Gajalakshmi V., Peto R., Kanaka T.S., and Jha P. Lancet 362 (2003) 507
17. Nair J., Pakhale S.S., and Bhide S.V. Food Chem. Toxicol. 27 (1989) 751
18. Kumar R., Siddiqi M., Tricker A.R., and Preussmann R. Food Chem. Toxicol. 29 (1991) 405
19. Pakhale S.S., and Maru G.B. Food Chem. Toxicol. 36 (1998) 1131
20. Cigarettes-Determination of Total and Nicotine Free Particulate Matter Using Routine Analytical Smoking Machine, International Organization for Standardization, Geneva, 1991, ISO 4387:1991 (E).
21. Counts M.E., Morton M.J., Laffoon S.W., Cox R.H., and Lipowicz P.J. Regul. Toxicol. Pharm. 41 (2005) 185