Pharmacokinetic properties of S-adenosylmethionine after oral and intravenous administration of its tosylate disulfate salt: A multiple-dose, open-label, parallel-group study in healthy Chinese volunteers

Clinical Therapeutics

Volumn 31, Issue 2, 2009, Pages 311-320

  Yang, Jin ^a   He, Ying ^a   Du, Ying Xiang ^a   Tang, Li Ling ^a   Wang, Guang Ji ^a   Fawcett, J Paul ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

enteric coated tablet; intravenous infusion; LC MS; pharmacokinetics; S adenosylmethionine

Indexed keywords

ACICLOVIR; S ADENOSYLMETHIONINE; S ADENOSYLMETHIONINE TOSYLATE SULFATE;

ABSENCE OF SIDE EFFECTS; ADULT; AGE DISTRIBUTION; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CHINESE; CONTROLLED STUDY; DIET RESTRICTION; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG METABOLISM; DRUG TOLERABILITY; ENTERIC COATED TABLET; FEMALE; HUMAN; HUMAN EXPERIMENT; ION MONITORING; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MULTIPLE DRUG DOSE; NORMAL HUMAN; OPEN STUDY; PARALLEL DESIGN; PHYSICIAN; SEX DIFFERENCE; SINGLE DRUG DOSE; VOLUNTEER;

ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG ADMINISTRATION SCHEDULE; FEMALE; HALF-LIFE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MASS SPECTROMETRY; S-ADENOSYLMETHIONINE; SEX FACTORS; TABLETS; YOUNG ADULT;

EID: 62149105544     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2009.02.010     Document Type: Article

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