Nuclear matrix as a target for hyperthermic killing of cancer cells

Cell Stress and Chaperones

Volumn 3, Issue 4, 1998, Pages 245-255

  Roti Roti, Joseph L ^a   Kampinga, Harm H ^b   Malyapa, Robert S ^a   Wright, William D ^a   VanderWaal, Robert P ^a   Xu, Mai ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; CHAPERONE; HEAT SHOCK PROTEIN 70; HETEROGENEOUS NUCLEAR RNA; NUCLEAR PROTEIN;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL DEATH; CELL KILLING; CELL NUCLEUS MATRIX; CELL PROLIFERATION; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; DNA TRANSCRIPTION; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PROTEIN INTERACTION; RNA PROCESSING; THERMOSTABILITY;

ANIMALIA;

EID: 0032434206     PISSN: 13558145     EISSN: None     Source Type: Journal    
DOI: 10.1379/1466-1268(1998)003<0245:NMAATF>2.3.CO;2     Document Type: Article

References (53)

1. Berezney R, Mortillaro MJ, Ma H, Wei X and Samarabandu J (1985) The nuclear matrix: A structural milieu for nuclear genomic function. In: Nuclear Matrix: Structural and Functional Organization, eds R Berezney and KW Jeon, Academic Press: 2-66
2. Bode J, Schlake T, Rios-Ramirez M, Mielke C, Stengert M, Kay V and Klehr-Wirth D (1995) Scaffold/matrix-attached regions: structural properties creating transcriptionally active Loci. In: Nuclear Matrix: Structural and Functional Organization, eds R Berezney and KW Jeon, Academic Press: 389-454.
3. Borrelli MJ, Lepock JR, Frey HE, Lee YJ and Corry PM (1996) Excess protein in nuclei isolated from heat shocked cells results from a reduced extractability of nuclear proteins. J Cell Physiol 167: 369-379
4. Calderwood SK and Hahn GM (1983) Thermal sensitivity and resistance of insulin-binding receptors. Biochim Biophys Acta 756: 1-8
5. Ciechanover A, Laszlo A, Bercovich B, Stancovski I, Ben-Neriah Y and Orian A (1996) The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators. Cold Spring Harbor Symposium, LX, "Protein Kinesis": 491-501
6. Feinberg A and Coffey DS (1982) In: The Nuclear Envelope and the Nuclear Matrix, ed GG Maul, Liss: 293-305
7. Felsenfeld G (1978) Chromatin. Nature 271: 115-122
8. Freeman BC and Morimoto RI (1996) The human cytosolic molecular chaperones Hsp90, Hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding. EMBO J 15: 2969-2979
9. Higashikubo R and Roti Roti JL (1993) Alterations in nuclear protein mass and macromolecular synthesis following heat shock. Radiat Res 134: 193-201
10. Kampinga HH (1993) Thermotolerance in mammalian cells: protein denaturation and aggregation and stress proteins. J Cell Sci 104: 11-17
11. Kampinga HH, Jorritsma JBM and Konings AWT (1985) Heat-induced alterations in DNA polymerase activity of HeLa cells and isolated nuclei. Relation to cell survival. J Radiat Biol 47: 29-40
12. Kampinga HH, Turkel-Uygur N, Roti Roti JL and Konings AWT (1989) The relationship of increased nuclear protein content induced by hyperthermia to killing of HeLa cells. Radiat Res 117: 511-522
13. Koehler DR and Hanawalt PC (1996) Recruitment of damaged DNA to the nuclear matrix in hamster cells following ultraviolet irradiation. Nucleic Acids Res 24: 2877-2884
14. Kornberg RD (1977) Structure of chromatin. Annu Rev Biochem 46: 931-954
15. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
16. Laszlo A (1992) The thermoresistant state: Protection from initial damage or better repair? Exp Cell Res 202: 519-531
17. Laszlo A and Li GC (1985) Heat-resistant variants of Chinese hamster fibroblasts altered in expression of heat shock protein. Proc Natl Acad.Sci USA 82: 8029-8033
18. Laszlo A, Wright W and Roti Roti JL (1992) Initial characterization of heat-induced excess nuclear proteins in HeLa cells. J Cell Physiol 151: 519-532
19. Laszlo A, Davidson T, Hu A, Landry J and Bedford J (1993) Putative determinants of the cellular response to hyperthermia. Int J Radiat Biol 63: 569-581
20. Lepock J (1982) Involvement of membranes in cellular responses to hyperthermia. Radiat Res 92: 433-438
21. Li GC, Mivechi NF and Weitzel G (1995) Heat shock proteins, thermotolerance and their relevance to clinical hyperthermia. Int J Hyperth 11: 459-488
22. Liu RY, Li X, Li L and Li GC (1992) Expression of human Hsp70 in rat fibroblasts enhances cell survival and facilitates recovery from translational and transcriptional inhibition following heat shock. Cancer Res 52: 3667-3673
23. Mackey MA (1993) In vitro effects and biological potential of long duration, moderate hyperthermia. In: Medical Radiology: Interstitial and intracavitary thermoradiotherapy, eds MH Seegenschmiedt and R. Sauer, Springer-Verlag, New York: 21-28
24. Mackey MA, Morgan WF and Dewey WC (1988) Nuclear fragmentation and premature chromosome condensation induced by heat shock in S-phase Chinese hamster ovary cells. Cancer Res 48: 6478-6483
25. Mackey MA, Anolik SL and Roti Roti JL (1992a) Cellular mechanisms associated with the lack of chronic thermotolerance development. Cancer Res 52: 1101-1106
26. Mackey MA, Anolik SL and Roti Roti JL (1992b) Changes in heat and radiation sensitivity during long duration, moderate hyperthermia in HeLa S3 cells. Int J Radiat Biol Oncol Phys 24: 543-550
27. Malyapa RS, Wright WD and Roti Roti JL (1994) Radiation sensitivity correlates with DNA supercoiling changes and nucleoid protein content in three Chinese hamster cell lines. Radiat Res 140: 312-320
28. Mirkovitch J, Mirault M-E and Laemmli UK (1984) Organization of the higher order chromatin loop: specific DNA attachment sites on the nuclear scaffold. Cell 39: 23-32
29. Nickerson JA, Krockmalnic G, He D and Penman S (1990) Immunolocalization in three dimensions: Immunogold staining of cytoskeletal and nuclear matrix proteins in resinless electron microscopy sections. Proc Natl Acad Sci USA 87: 2259-2263
30. Nickerson JA, Blencowe BJ and Penman S (1995) The architectural organization of nuclear metabolism. In: Nuclear Matrix: Structural and Functional Organization, eds R Berezney and KW Jeon, Academic Press, London: 67-123
31. Noterman JA and Gerner EA (1982) Thermal stability of ornithin decarboxylase. In: Third International Symposium: Cancer Therapy by Hyperthermia, Drugs and Radiation, ed LA Dethlefsen, JNCI Monographs 61: 69-72
32. Ohtsuka K and Laszlo A (1992) The relationship between Hsp70 localization and heat resistance. Exp Cell Res 202: 507-518
33. Roti Roti JL (1982) Heat-induced cell death and radiosensitization: Molecular mechanisms. In: Third International Symposium: Cancer Therapy by Hyperthermia, Drugs and Radiation, ed LA Dethlefsen, JNCI Monographs 61:45-47
34. Roti Roti JL and Laszlo A (1988) The effects of hyperthermia on cellular macromolecules. In: Hyperthermia and Oncology, Vol. 1, Thermal Effects on Cells and Tissues, eds M Urano and E Douple, VSP, The Netherlands: 13-56
35. Roti Roti JL and Turkel N (1994a) Heat shock-induced changes in nuclear protein and cell killing in thermotolerant HeLa cells. Radiat Res 138: 286-290
36. Roti Roti JL and Turkel N (1994b) Heat-induced changes in nuclear-associated proteins in normal and thermotolerant HeLa cells. Radiat Res 139: 73-81
37. Roti Roti JL and Winward RT (1978) The effects of hyperthermia on the protein to DNA ratio of isolated HeLa chromatin. Radiat Res 74: 159-169
38. Roti Roti JL and Winward RT (1980) Factors affecting the heat-induced increase in protein content of chromatin. Radiat Res 81: 138-144
39. Roti Roti JL and Wright WD (1987) Visualization of DNA loops in nucleoids from HeLa cells: Assays for DNA damage and repair. Cytometry 8: 461-467
40. Schlegel R and Pardee A (1986) Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells. Science 232: 1264-1266
41. Tomasovic SP, Turner GN and Dewey WG (1978) Effects of hyperhermia on nonhistone proteins isolated with DNA. Radiat Res 73: 535-552
42. Towbin H, Staehelin T and Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354
43. Tubo RA and Berezney R (1987) Identification of 100 and 150 S DNA polymerase alpha-primase megacomplexes solubolized from the nuclear matrix of regenerating rat liver. J Biol Chem 262:5857-5865
44. vanderWaal R, Thampy G, Wright WD and Roti Roti JL (1996) Heat-induced modifications in the association of specific proteins with the nuclear matrix. Radiat Res 145:746-753
45. vanderWaal R, Malyapa RS, Higashikubo R and Roti Roti JL (1997) A comparison of the modes and kinetics of heat-induced cell killing in HeLa and L5178Y cells. Radiat Res 148: 455-462
46. Vemuri MC, Raju NN and Malhotra SK (1993) Recent advances in nuclear matrix function. Cytobios 76: 117-128
47. Wachsberger PR and Coss RA (1993) Alterations in nuclear matrix ultrastructure of G1 mammalian cells following heat shock: resinless section electron microscopy, biochemical and immunofluorescence studies. J Cell Physiol 155: 615-634
48. Wang Z and Droge P (1997) Long-range effects in a supercoiled DNA domain generated by transcription in vitro. J Mol Biol 271: 499-510
49. Warters RL, Yasui LS, Sharma R and Roti Roti JL (1986) Heat shock (45°C) results in an increase on nuclear matrix protein mass in HeLa cells. Int J Radiat Biol 50: 253-259
50. Warters RL, Chu GL, Wong RSL, Lyons BW and Dewey WC (1993) Nuclear protein redistribution in heat shocked cells. J Cell Physiol 154: 402-409
51. Worcel A and Benyajati C (1977) Higher order coiling of DNA in chromatin. Cell 12: 83-100
52. Wright WD, Higashikubo R and Roti Roti JL (1989) Flow cytometric studies of the nuclear matrix. Cytometry 10: 303-311
53. Xu M, Wright WD, Higashikubo R and Roti Roti JL (1996) Chronic thermotolerance with continued cell proliferation. Int J Hyperther 12: 645-660