Glucose-dependent and -independent electrical activity in islets of Langerhans of Psammomys obesus, an animal model of nutritionally induced obesity and diabetes

General and Comparative Endocrinology

Volumn 161, Issue 2, 2009, Pages 193-201

  Zimliki, Charles L ^a,b   Chenault, V Michelle ^a,b   Mears, David ^a,c  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b CENTER FOR DEVICES AND RADIOLOGICAL HEALTH   (United States)

^c UNIVERSITY OF CHILE   (Chile)

Author keywords

Calcium; Electrophysiology; Insulin; Oscillation; Pancreatic cell; Sand rat

Indexed keywords

DIAZOXIDE; GLUCOSE; INSULIN; POTASSIUM CHANNEL;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CELL SUBPOPULATION; CONTROLLED STUDY; DOSE RESPONSE; ELECTRIC ACTIVITY; FEMALE; INSULIN RELEASE; INTRACELLULAR RECORDING; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OSCILLATION; PANCREAS ISLET; PANCREAS ISLET CELL; PRIORITY JOURNAL; PSAMMOMYS OBESUS; RAT;

EID: 62049086233     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2008.12.017     Document Type: Article

References (51)

1. Antunes C.M., Salgado A.P., Rosario L.M., and Santos R.M. Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets. Diabetes 49 (2000) 2028-2038
2. Barg S., Galvanovskis J., Gopel S.O., Rorsman P., and Eliasson L. Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting α-cells. Diabetes 49 (2000) 1500-1510
3. 2+ oscillation frequency and insulin exocytosis. Cell 119 (2004) 273-284
4. 2+, and metabolism for plasma insulin oscillations. Diabetes 51 Suppl. 1 (2002) S171-S176
5. Bertram R., Previte J., Sherman A., Kinard T.A., and Satin L.S. The phantom burster model for pancreatic β-cells. Biophys. J. 79 (2000) 2880-2892
6. Bertram R., Satin L., Zhang M., Smolen P., and Sherman A. Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys. J. 87 (2004) 3074-3087
7. Bertram R., Satin L.S., Pedersen M.G., Luciani D.S., and Sherman A. Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets. Biophys. J. 92 (2007) 1544-1555
8. 2+ signaling. Endocrinology 137 (1996) 693-697
9. Chan C.B. β-cell stimulus-secretion coupling defects in rodent models of obesity. Can. J. Physiol. Pharmacol. 73 (1995) 1414-1424
10. Chay T.R. Electrical bursting and luminal calcium oscillation in excitable cell models. Biol. Cybern. 75 (1996) 419-431
11. Chay T.R. Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic β-cells. Biophys. J. 73 (1997) 1673-1688
12. Dean P.M., and Matthews E.K. Electrical activity in pancreatic islet cells. Nature 219 (1968) 389-390
13. Diederichs F. Mathematical simulation of membrane processes and metabolic fluxes of the pancreatic β-cell. Bull. Math. Biol. 68 (2006) 1779-1818
14. Donath M.Y., Gross D.J., Cerasi E., and Kaiser N. Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48 (1999) 738-744
15. Duttaroy A., Zimliki C.L., Gautam D., Cui Y., Mears D., and Wess J. Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in M3 muscarinic acetylcholine receptor-deficient mice. Diabetes 53 (2004) 1714-1720
16. 2+ as evidences in single pancreatic islets. J. Biol. Chem. 268 (1993) 22265-22268
17. Gopel S., Kanno T., Barg S., Galvanovskis J., and Rorsman P. Voltage-gated and resting membrane currents recorded from β-cells in intact mouse pancreatic islets. J. Physiol. 521 (1999) 717-728
18. Gopel S.O., Kanno T., Barg S., and Rorsman P. Patch-clamp characterisation of somatostatin-secreting cells in intact mouse pancreatic islets. J. Physiol. 528 (2000) 497-507
19. Ikeuchi M., Fujimoto W.Y., and Cook D.L. Rat islet cells have glucose-dependent periodic electrical activity. Horm. Metab. Res. 16 (1984) 125-127
20. 2+ oscillations in clusters of mouse pancreatic islet cells. J. Physiol. 520 (1999) 839-849
21. Kinard T.A., de Vries G., Sherman A., and Satin L.S. Modulation of the bursting properties of single mouse pancreatic β-cells by artificial conductances. Biophys. J. 76 (1999) 1423-1435
22. 2+ in mouse pancreatic islets. J. Physiol. 508 (1998) 471-481
23. MacDonald P.E., Joseph J.W., and Rorsman P. Glucose-sensing mechanisms in pancreatic β-cells. Philos. Trans. R. Soc. Lond. B Biol. Sci. 360 (2005) 2211-2225
24. Manning Fox J.E., Gyulkhandanyan A.V., Satin L.S., and Wheeler M.B. Oscillatory membrane potential response to glucose in islet β-cells: a comparison of islet-cell electrical activity in mouse and rat. Endocrinology 147 (2006) 4655-4663
25. Massa M.L., Borelli M.I., Del Zotto H., and Gagliardino J.J. Changes induced by sucrose administration on glucose metabolism in pancreatic islets in normal hamsters. J. Endocrinol. 171 (2001) 551-556
26. Mears D., and Atwater I. Electrophysiology of the pancreatic β-cell. In: LeRoith D., Taylor S.I., and Olefsky J.M. (Eds). Diabetes Mellitus - A Fundamental and Clinical Text. 2nd ed. (2000), Lippincott, Williams & Wilkins, Philadelphia 47-60
27. Mears D., Leighton X., Atwater I., and Rojas E. Tetracaine stimulates insulin secretion from the pancreatic β-cell by release of intracellular calcium. Cell Calcium 25 (1999) 59-68
28. Mears D., Sheppard Jr. N., Atwater I., Rojas E., Bertram R., and Sherman A. Evidence that calcium release-activated current mediates the biphasic electrical activity of mouse pancreatic β-cells. J. Membr. Biol. 155 (1997) 47-59
29. Mears D., Sheppard Jr. N.F., Atwater I., and Rojas E. Magnitude and modulation of pancreatic β-cell gap junction electrical conductance in situ. J. Membr. Biol. 146 (1995) 163-176
30. Meda P., Atwater I., Goncalves A., Bangham A., Orci L., and Rojas E. The topography of electrical synchrony among β-cells in the mouse islet of Langerhans. Q. J. Exp. Physiol. 69 (1984) 719-735
31. Meissner H.P. Membrane potential measurements in pancreatic β-cells with intracellular microelectrodes. Methods Enzymol. 192 (1990) 235-246
32. Meissner H.P., and Schmelz H. Membrane potential of β-cells in pancreatic islets. Pflügers Arch. 351 (1974) 195-206
33. Meissner H.P., and Schmidt H. The electrical activity of pancreatic β-cells of diabetic mice. FEBS Lett. 67 (1976) 371-374
34. Miley H.E., Sheader E.A., Brown P.D., and Best L. Glucose-induced swelling in rat pancreatic β-cells. J. Physiol. 504 (1997) 191-198
35. Nesher R., Gross D.J., Donath M.Y., Cerasi E., and Kaiser N. Interaction between genetic and dietary factors determines β-cell function in Psammomys obesus, an animal model of type 2 diabetes. Diabetes 48 (1999) 731-737
36. Nunemaker C.S., Zhang M., Wasserman D.H., McGuinness O.P., Powers A.C., Bertram R., Sherman A., and Satin L.S. Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?. Diabetes 54 (2005) 3517-3522
37. Palti Y., David G.B., Lachov E., Mida Y.H., and Schatzberger R. Islets of Langerhans generate wavelike electric activity modulated by glucose concentration. Diabetes 45 (1996) 595-601
38. Pedersen M.G. Phantom bursting is highly sensitive to noise and unlikely to account for slow bursting in β-cells: considerations in favor of metabolically driven oscillations. J. Theor. Biol. 248 (2007) 391-400
39. Pertusa J.A., Nesher R., Kaiser N., Cerasi E., Henquin J.C., and Jonas J.C. Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes. Diabetes 51 (2002) 2552-2560
40. + permeability. Q. J. Exp. Physiol. 70 (1985) 137-150
41. Rosario L.M., Atwater I., and Scott A.M. Pulsatile insulin release and electrical activity from single ob/ob mouse islets of Langerhans. Adv. Exp. Med. Biol. 211 (1986) 413-425
42. i oscillations due to bursting electrical activity in single pancreatic islets. Pflügers Arch. 418 (1991) 417-422
43. Schuit F.C. Factors determining the glucose sensitivity and glucose responsiveness of pancreatic β-cells. Horm. Res. 46 (1996) 99-106
44. Scott A.M., Dawson C.M., and Goncalves A.A. Comparison of glucose-induced changes in electrical activity, insulin release, lactate output and potassium permeability between normal and ob/ob mouse islets: effects of cooling. J. Endocrinol. 107 (1985) 265-273
45. Shafrir E., Ziv E., and Kalman R. Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil). ILAR J. 47 (2006) 212-224
46. Smith P.A., Ashcroft F.M., and Rorsman P. Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic β-cells. FEBS Lett. 261 (1990) 187-190
47. 2+ concentration resembling bursting electrical activity in single mouse islets of Langerhans. FEBS Lett. 259 (1989) 19-23
48. Wagoner P.K., Chen C., Worley J.F., Dukes I.D., and Oxford G.S. Amylin modulates β-cell glucose sensing via effects on stimulus-secretion coupling. Proc. Natl. Acad. Sci. USA 90 (1993) 9145-9149
49. Worley III J.F., McIntyre M.S., Spencer B., Mertz R.J., Roe M.W., and Dukes I.D. Endoplasmic reticulum calcium store regulates membrane potential in mouse islet β-cells. J. Biol. Chem. 269 (1994) 14359-14362
50. 2+ dynamics of isolated mouse β-cells and islets: implications for mathematical models. Biophys. J. 84 (2003) 2852-2870
51. Zimliki C.L., Mears D., and Sherman A. Three roads to islet bursting: emergent oscillations in coupled phantom bursters. Biophys. J. 87 (2004) 193-206