Effect of elevated local temperature on cutaneous vasoconstrictor responsiveness in humans

Journal of Applied Physiology

Volumn 106, Issue 2, 2009, Pages 571-575

  Wingo, Jonathan E ^a,b   Low, David A ^a   Keller, David M ^a,b   Brothers, R Matthew ^a   Shibasaki, Manabu ^c   Crandall, Craig G ^a,b  

^a PRESBYTERIAN HOSPITAL OF DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NARA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Microdialysis; Nitric oxide; Norepinephrine; Skin temperature; Tyramine

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NORADRENALIN; TYRAMINE; ADENOSINE; ADRENERGIC RECEPTOR AFFECTING AGENT; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HEATING; HUMAN; HUMAN EXPERIMENT; MALE; MICRODIALYSIS; NEUROTRANSMITTER RELEASE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD FLOW; SKIN TEMPERATURE; VASOCONSTRICTION; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD VESSEL; BODY TEMPERATURE; DOSE RESPONSE; DRUG ANTAGONISM; FOREARM; HEAT; HEAT INJURY; INNERVATION; LASER DOPPLER FLOWMETRY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; REGRESSION ANALYSIS; SKIN; SYNAPTOSOME; VASCULARIZATION;

ADENOSINE; ADRENERGIC UPTAKE INHIBITORS; ADULT; BLOOD FLOW VELOCITY; BLOOD VESSELS; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FEMALE; FOREARM; HEAT STRESS DISORDERS; HOT TEMPERATURE; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; MICRODIALYSIS; MIDDLE AGED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; NOREPINEPHRINE; PRESYNAPTIC TERMINALS; REGIONAL BLOOD FLOW; REGRESSION ANALYSIS; SKIN; TYRAMINE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 61949199755     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.91249.2008     Document Type: Article

References (33)

1. 2C-adrenoceptor translocation. Circ Res 94: 1367-1374, 2004.
2. Bailey SR, Mitra S, Flavahan S, Flavahan NA. Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries. Am J Physiol Heart Circ Physiol 289: H243-H250, 2005. (Pubitemid 40934106)
3. Boels PJ, Verbeuren TJ, Vanhoutte PM. Moderate cooling depresses the accumulation and the release of newly synthesized catecholamines in isolated canine saphenous veins. Experientia 41: 1374-1377, 1985.
4. Cooke JP, Shepherd JT, Vanhoutte PM. The effect of warming on adrenergic neurotransmission in canine cutaneous vein. Circ Res 54: 547-553, 1984.
5. Costa F, Christensen NJ, Farley G, Biaggioni I. NO modulates norepinephrine release in human skeletal muscle: implications for neural preconditioning. Am J Physiol Regul Integr Comp Physiol 280: R1494-R1498, 2001.
6. Durand S, Davis SL, Cui J, Crandall CG. Exogenous nitric oxide inhibits sympathetically mediated vasoconstriction in human skin. J Physiol 562: 629-634, 2005.
7. 2-adrenoceptors as cutaneous thermosensors. News Physiol Sci 6: 251-255, 1991.
8. Fox RH, Goldsmith R, Hampton IF, Hunt TJ. Heat acclimatization by controlled hyperthermia in hot-dry and hot-wet climates. J Appl Physiol 22: 39-46, 1967.
9. Greenberg SS, Diecke FP, Peevy K, Tanaka TP. Release of norepinephrine from adrenergic nerve endings of blood vessels is modulated by endothelium-derived relaxing factor. Am J Hypertens 3: 211-218, 1990. (Pubitemid 20166161)
10. Habler HJ, Wasner G, Janig W. Attenuation of neurogenic vasoconstriction by nitric oxide in hindlimb microvascular beds of the rat in vivo. Hypertension 30: 957-961, 1997. (Pubitemid 27441129)
11. Hodges GJ, Kosiba WA, Zhao K, Alvarez GE, Johnson JM. The role of baseline in the cutaneous vasoconstrictor responses during combined local and whole body cooling in humans. Am J Physiol Heart Circ Physiol 293: H3187-H3192, 2007. (Pubitemid 350106546)
12. Johnson JM, Proppe DW. Cardiovascular adjustments to heat stress. In: Handbook of Physiology. Environmental Physiology. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol.I, chapt. 11, p. 215-243.
13. Kellogg DL Jr, Liu Y, Kosiba IF, O'Donnell D. Role of nitric oxide in the vascular effects of local warming of the skin in humans. J Appl Physiol 86: 1185-1190, 1999. (Pubitemid 29172150)
14. Kolo LL, Westfall TC, Macarthur H. Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed. Am J Physiol Heart Circ Physiol 286: H296-H303, 2004.
15. Lind AR, Leithead CS, McNicol GW. Cardiovascular changes during syncope induced by tilting men in the heat. J Appl Physiol 25: 268-276, 1968.
16. Low DA, Shibasaki M, Davis SL, Keller DM, Crandall CG. Does local heating-induced nitric oxide production attenuate vasoconstrictor responsiveness to lower body negative pressure in human skin? J Appl Physiol 102: 1839-1843, 2007.
17. Minson CT, Berry LT, Joyner MJ. Nitric oxide and neurally mediated regulation of skin blood flow during local heating. J Appl Physiol 91: 1619-1626, 2001.
18. Minson CT, Holowatz LA, Wong BJ, Kenney WL, Wilkins BW. Decreased nitric oxide- and axon reflex-mediated cutaneous vasodilation with age during local heating. J Appl Physiol 93: 1644-1649, 2002.
19. Nadel ER, Stolwijk AJ. Effect of skin wettedness on sweat gland response. J Appl Physiol 35: 689-694, 1973.
20. O'Leary DS. Regional vascular resistance vs. conductance: which index for baroreflex responses? Am J Physiol Heart Circ Physiol 260: H632-H637, 1991.
21. Piwonka RW, Robinson S. Acclimatization of highly trained men to work in severe heat. J Appl Physiol 22: 9-12, 1967.
22. Rowell LB. Circulatory adjustments to dynamic exercise and heat stress: competing controls. In: Human Circulation: Regulation During Physical Stress. New York: Oxford University Press, 1986, p. 363-406.
23. Rowell LB, Brengelmann GL, Murray JA. Cardiovascular responses to sustained high skin temperature in resting man. J Appl Physiol 27: 673-680, 1969.
24. Shibasaki M, Durand S, Davis SL, Cui J, Low DA, Keller DM, Crandall CG. Endogenous nitric oxide attenuates neutrally-mediated cutaneous vasoconstriction. J Physiol 585: 627-634, 2007. (Pubitemid 350193930)
25. Shibasaki M, Low DA, Davis SL, Crandall CG. Nitric oxide inhibits cutaneous vasoconstriction to exogenous norepinephrine. J Appl Physiol 105: 1504-1508, 2008.
26. Taylor WF, Johnson JM, O'Leary DS, Park MK. Modification of the cutaneous vascular response to exercise by local skin temperature. J Appl Physiol 57: 1878-1884, 1984.
27. Thompson-Torgerson CS, Holowatz LA, Flavahan NA, Kenney WL. Cold-induced cutaneous vasoconstriction is mediated by Rho kinase in vivo in human skin. Am J Physiol Heart Circ Physiol 292: H1700-H1705, 2007.
28. Vanhoutte PM, Shepherd JT. Effect of temperature on reactivity of isolated cutaneous veins of the dog. Am J Physiol 218: 187-190, 1970.
29. Wilson TE, Cui J, Crandall CG. Effect of whole-body and local heating on cutaneous vasoconstrictor responses in humans. Auton Neurosci 97: 122-128, 2002. (Pubitemid 34603136)
30. Wilson TE, Cui J, Zhang R, Witkowski S, Crandall CG. Skin cooling maintains cerebral blood flow velocity and orthostatic tolerance during tilting in heated humans. J Appl Physiol 93: 85-91, 2002. (Pubitemid 34686197)
31. Wong BJ, Wilkins BW, Holowatz LA, Minson CT. Nitric oxide synthase inhibition does not alter the reactive hyperemic response in the cutaneous circulation. J Appl Physiol 95: 504-510, 2003.
32. Wyndham CH, Rogers GG, Senay LC, Mitchell D. Acclimization in a hot, humid environment: cardiovascular adjustments. J Appl Physiol 40: 779-785, 1976.
33. Zanzinger J, Czachurski J, Seller H. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res 75: 1073-1077, 1994. (Pubitemid 24351452)