Does local heating-induced nitric oxide production attenuate vasoconstrictor responsiveness to lower body negative pressure in human skin?

Journal of Applied Physiology

Volumn 102, Issue 5, 2007, Pages 1839-1843

  Low, David A ^a   Shibasaki, Manabu ^a   Davis, Scott L ^b   Keller, David M ^b   Crandall, Craig G ^a,b  

^a PRESBYTERIAN HOSPITAL OF DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cutaneous microdialysis; Nitric oxide; Orthostatic stress; Skin blood flow

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ADULT; ARTICLE; BLOOD FLOW; BODY TEMPERATURE; CONTROLLED STUDY; FEMALE; HEATING; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; MALE; MICRODIALYSIS; ORTHOSTATIC STRESS; PRESSURE; PRIORITY JOURNAL; SKIN; THERMOREGULATION; VASOCONSTRICTION;

ADENOSINE; ADULT; BLOOD PRESSURE; ENDOTHELIUM-DEPENDENT RELAXING FACTORS; ENZYME INHIBITORS; FEMALE; HEART RATE; HEAT; HUMANS; HYPOTENSION, ORTHOSTATIC; LOWER BODY NEGATIVE PRESSURE; MALE; MICRODIALYSIS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REGIONAL BLOOD FLOW; RESEARCH DESIGN; SKIN; SKIN TEMPERATURE; VASOCONSTRICTION;

EID: 34247869585     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01181.2006     Document Type: Article

References (26)

1. Cooke JP, Shepherd JT, Vanhoutte PM. The effect of warming on adrenergic neurotransmission in canine cutaneous vein. Circ Res 54: 547-553, 1984.
2. Costa F, Christensen NJ, Farley G, Biaggioni I. NO modulates norepinephrine release in human skeletal muscle: implications for neural preconditioning. Am J Physiol Regul Integr Comp Physiol 280: R1494-R1498, 2001.
3. Crandall CG, MacLean DA. Cutaneous interstitial nitric oxide concentration does not increase during heat stress in humans. J Appl Physiol 90: 1020-1024, 2001.
4. Durand S, Davis SL, Cui J, Crandall CG. Exogenous nitric oxide inhibits sympathetically mediated vasoconstriction in human skin. J Physiol 562: 629-634, 2005.
5. Greenberg SS, Diecke FP, Peevy K, Tanaka TP. Release of norepinephrine from adrenergic nerve endings of blood vessels is modulated by endothelium-derived relaxing factor. Am J Hypertens 3: 211-218, 1990.
6. Johnson JM, Brengelmann GL, Rowell LB. Interactions between local and reflex influences on human forearm skin blood flow. J Appl Physiol 41: 826-831, 1976.
7. Johnson JM, O'Leary DS, Taylor WF, Kosiba W. Effect of local warming on forearm reactive hyperaemia. Clin Physiol 6: 337-346, 1986.
8. Kellogg DL Jr, Johnson JM, Kosiba WA. Baroreflex control of the cutaneous active vasodilator system in humans. Circ Res 66: 1420-1426, 1990.
9. Kellogg DL Jr, Liu Y, Kosiba IF, O'Donnell D. Role of nitric oxide in the vascular effects of local warming of the skin in humans. J Appl Physiol 86: 1185-1190, 1999.
10. Kellogg DL Jr, Zhao JL, Friel C, Roman LJ. Nitric oxide concentration increases in the cutaneous interstitial space during heat stress in humans. J Appl Physiol 94: 1971-1977, 2003.
11. Kolo LL, Westfall TC, Macarthur H. Nitric oxide decreases the biological activity of norepinephrine resulting in altered vascular tone in the rat mesenteric arterial bed. Am J Physiol Heart Circ Physiol 286: H296-H303, 2004.
12. Kregel KC, Gisolfi CV. Circulatory responses to vasoconstrictor agents during passive heating in the rat. J Appl Physiol 68: 1220-1227, 1990.
13. Lind AR, Leithead CS, McNicol GW. Cardiovascular changes during syncope induced by tilting men in the heat. J Appl Physiol 25: 268-276, 1968.
14. Massett MP, Lewis SJ, Kregel KC. Effect of heating on the hemodynamic responses to vasoactive agents. Am J Physiol Regul Integr Comp Physiol 275: R844-R853, 1998.
15. Meendering JR, Torgrimson BN, Houghton BL, Halliwill JR, Minson CT. Menstrual cycle and sex affect hemodynamic responses to combined orthostatic and heat stress. Am J Physiol Heart Circ Physiol 289: H631-H642, 2005.
16. Minson CT, Berry LT, Joyner MJ. Nitric oxide and neurally mediated regulation of skin blood flow during local heating. J Appl Physiol 91: 1619-1626, 2001.
17. Rowell LB, Brengelmann GL, Murray JA. Cardiovascular responses to sustained high skin temperature in resting man. J Appl Physiol 27: 673-680, 1969.
18. Rowell LB, Wyss CR, Brengelmann GL. Sustained human skin and muscle vasoconstriction with reduced baroreceptor activity. J Appl Physiol 34: 639-643, 1973.
19. Taylor WF, Johnson JM, O'Leary D, Park MK. Effect of high local temperature on reflex cutaneous vasodilation. J Appl Physiol 57: 191-196, 1984.
20. Tripathi A, Nadel ER. Forearm skin and muscle vasoconstriction during lower body negative pressure. J Appl Physiol 60: 1535-1541, 1986.
21. Vanhoutte PM, Cooke JP, Lindblad LE, Shepherd JT, Flavahan NA. Modulation of postjunctional alpha-adrenergic responsiveness by local changes in temperature. Clin Sci (Lond) 68, Suppl 10: 121s-123s, 1985.
22. Vanhoutte PM, Shepherd JT. Effect of temperature on reactivity of isolated cutaneous veins of the dog. Am J Physiol 218: 187-190, 1970.
23. Vissing SF, Scherrer U, Victor RG. Increase of sympathetic discharge to skeletal muscle but not to skin during mild lower body negative pressure in humans. J Physiol 481: 233-241, 1994.
24. Wilson TE, Cui J, Crandall CG. Effect of whole-body and local heating on cutaneous vasoconstrictor responses in humans. Auton Neurosci 97: 122-128, 2002.
25. Wilson TE, Cui J, Zhang R, Witkowski S, Crandall CG. Skin cooling maintains cerebral blood flow velocity and orthostatic tolerance during tilting in heated humans. J Appl Physiol 93: 85-91, 2002.
26. Zanzinger J, Czachurski J, Seller H. Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res 75: 1073-1077, 1994.