A20 overexpression inhibits low shear flow-induced CD14-positive monocyte recruitment to endothelial cells

Biorheology

Volumn 46, Issue 1, 2009, Pages 21-30

  Zeng, Wen ^a   Li, Li ^a   Yuan, Wei ^a   Wei, Yong ^a   Mi, Jianhong ^a   Sun, Jiansen ^a   Wen, Can ^a   Zhang, Wei ^a   Ying, Dajun ^a   Zhu, Chuhong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

A20 gene; Atherosclerosis; Hemodynamics; I B ; Monocyte; VCAM 1

Indexed keywords

CD14 ANTIGEN; I KAPPA B ALPHA; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MESSENGER RNA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN A20;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; POLYMERASE CHAIN REACTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SHEAR FLOW;

ANTIGENS, CD14; AORTA; CELL ADHESION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMANS; I-KAPPA B PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-8; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MONOCYTES; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STRESS, MECHANICAL; TRANSFECTION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 61949109190     PISSN: 0006355X     EISSN: None     Source Type: Journal    
DOI: 10.3233/BIR-2009-0523     Document Type: Article

References (28)

1. Y. Abe, K. Sugisaki and A.M. Dannenberg Jr., Rabbit vascular endothelial adhesion molecules: ELAM-1 is most elevated in acute inflammation, whereas VCAM-1 and ICAM-1 predominate in chronic inflammation, J. Leukoc. Biol. 60 (1996), 692-703.
2. E.O. Apostolov, S.V. Shah, E. Ok and A.G. Basnakian, Carbamylated low-density lipoprotein induces monocyte adhesion to endothelial cells through Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1, Arterioscler. Thromb. Vasc. Biol. 27 (2007), 826-832.
3. T. Asakura and T. Karino, Flow patterns and spatial distribution of atherosclerotic lesions inhuman coronary arteries, Circ. Res. 66 (1990), 1045-1066.
4. C. Cheng, D. Tempel, R. van Haperen, A. van der Baan et al., Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress, Circulation 113 (2006), 2744-2753.
5. S.A. Cook, M.S. Novikov, Y. Ahn, T. Matsui and A. Rosenzweig, A20 is dynamically regulated in the heart and inhibits the hypertrophic response, Circulation 108 (2003), 638-640.
6. J.T. Cooper, D.M. Stroka, C. Brostjan, A. Palmetshofer et al., A20 blocks endothelial cell activation through a NF-kappaBdependent mechanism, J. Biol. Chem. 271 (1996), 18068-18073.
7. A.M. Fogelman, F. Elahi, K. Sykes, B.J. Van Lenten et al., Modification of the Recalde method for the isolation of human monocytess, J. Lipid Res. 29 (1988), 1243-1247.
8. P.S. Gargalovic, N.M. Gharavi, M.J. Clark, J. Pagnon et al., The unfolded protein response is an important regulator of inflammatory genes in endothelial cells, Arterioscler. Thromb. Vasc. Biol. 26 (2006), 2490-2496.
9. R.E. Gerszten, Y.C. Lim, H.T. Ding, K. Snapp et al., Adhesion of monocytes to Vascular Cell Adhesion Molecule-1-transduced human endothelial cells: implications for atherogenesis, Circ. Res. 82 (1998), 871-878.
10. K. Heyninck, D.D. Valck, W.V. Berghe et al., The Zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NFkappaB-inhibiting protein ABIN, J. Cell. Biol. 145 (1999), 1471-1482.
11. I. Inoue, K. Shino, S. Noji, T. Awata and S. Katayama, Expression of peroxisome proliferator-activated receptor- (PPAR-) in primary cultures of human vascular endothelial cells, Biochem. Biophys. Res. Commun. 246 (1998), 370-374.
12. A. Krikos, C.D. Laherty and V.M. Dixit, Transcriptional activation of the TNF-inducible zinc finger protein, A20, is mediated by kappaB elements, J. Biol. Chem. 267 (1992), 17971-17976.
13. U. Kunter, I. Floege, A.S. von Jurgensonn, T. Stojanovic et al., Expression of A20 in the vessel wall of rat-kidney allografts correlates with protection from transplant arteriosclerosis, Transplantation 75 (2003), 3-9.
14. E.G. Lee, D.L. Boone, S. Chai, S.L. Libby et al., Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice, Science 289 (2000), 2350-2354.
15. C.R. Longo, M.B. Arvelo, V.I. Patel, S. Daniel et al., A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis, Circulation 108 (2003), 1113-1118.
16. N. Marui, M.K. Offerman, R. Swerlick, C. Kunsch et al., Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells, J. Clin. Invest. 92 (1993), 1866-1874.
17. S. Mohan, M. Hamuro, G.P. Sorescu, K. Koyoma et al., IkappaBalpha- dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide, Am. J. Physiol. Cell Physiol. 284 (2003), C1039-C1047.
18. S. Mohan, N. Mohan, A.J. Valente and E.A. Sprague, Regulation of low shear flow-induced HAEC VCAM-1 expression and monocyte adhesion, Am. J. Physiol. 276 (1999), C1100-C1107.
19. P.R. Moreno, E. Falk, I.F. Palacios, J.B. Newell et al., Macrophage infiltration in acute coronary syndromes: implications for plaque rupture, Circulation 90 (1994), 775-778.
20. T. Nagel, N. Resnick, C.F. Dewey Jr. and M.A. Gimbrone Jr., Vascular endothelial cells respond to spatial gradients in fluid shear stress by enhanced activation of transcription factors, Arterioscler. Thromb. Vasc. Biol. 19 (1999), 1825-1834.
21. A.W. Opipari Jr., M.S. Boguski and V.M. Dixit, The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein, J. Biol. Chem. 265 (1990), 14705-14708.
22. A.W. Opipari Jr., H.M. Hu, R. Yabkowitz and V.M. Dixit, The A20 zinc finger protein protects cells from TNF cytotoxicity, J. Biol. Chem. 267 (1992), 12424-12427.
23. S.M. O'Reilly and P.N. Moynagh, Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein, Biochem. Biophys. Res. Commun. 303 (2003), 586-593.
24. E.A. Sprague and J. Luo, Prolonged low shear stress flow conditioning of cultured human aortic endothelial cells enhances monocyte adhesion, MCP-1, and VCAM-1 expression, Circulation 90 (1994), I-84.
25. F.S. Zetoune, A.R. Murthy, Z. Shao, T. Hlaing et al., A20 inhibits NF-kappa B activation downstream of multiple Map3 kinases and interacts with the I kappa B signalosome, Cytokine 15 (2001), 282-298.
26. S.Q. Zhang, A. Kovalenko, G. Cantarella and D. Wallach, Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation, Immunity 12 (2000), 301-311.
27. C.H. Zhu, D.J. Ying, J.H. Mi, W. Zhang et al., The zinc finger protein A20 Gene protects endothelial cells from Burns Serum injury, Burns 30 (2004), 127-133.
28. C.H. Zhu, D.J. Ying, J.H. Mi, X.H. Zhu et al., Low shear stress regulates monocyte adhesion to oxidized lipid-induced endothelial cells via an IκBα dependent pathway, Biorheology 41 (2004), 127-137.