Experimental forearm immobilization in humans reduces capsaicin-induced pain and flare

Brain Research

Volumn 1263, Issue , 2009, Pages 43-49

  Terkelsen, Astrid Juhl ^a   Bach, Flemming Winther ^a,b   Jensen, Troels Staehelin ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Capsaicin; Cast immobilization; Complex regional pain syndrome; Human pain model; Neurogenic inflammation; Skin temperature

Indexed keywords

CAPSAICIN; SUBSTANCE P;

ARM MOVEMENT; ARTICLE; BLOOD FLOWMETRY; CAST APPLICATION; COMPLEX REGIONAL PAIN SYNDROME; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN EXPERIMENT; MECHANICAL STIMULATION; NERVE FIBER; NEUROGENIC INFLAMMATION; NORMAL HUMAN; PAIN; PRIORITY JOURNAL; SCAPHOID BONE; SIGNAL TRANSDUCTION; SKIN BLOOD FLOW; SKIN TEMPERATURE; VASODILATATION;

ADOLESCENT; ADULT; AREA UNDER CURVE; CAPSAICIN; FEMALE; FOREARM; HAND; HUMANS; IMMOBILIZATION; MALE; PAIN; PAIN MEASUREMENT; REGIONAL BLOOD FLOW; SKIN; SKIN PHYSIOLOGICAL PHENOMENA; SKIN TEMPERATURE; SUBSTANCE P; TIME FACTORS; YOUNG ADULT;

RATTUS;

EID: 61849161668     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.01.054     Document Type: Article

References (41)

1. Baron R., Blumberg H., and Janig W. Clinical characteristics of patients with complex regional pain syndrome in Germany with special emphasis on vasomotor function. In: Janig W., and Stanton-Hicks M. (Eds). Reflex Sympathetic Dystrophy: A Reappraisal. Progress in Pain Research and Management (1996), IASP press, Seattle 25-48
2. Baron R. Complex regional pain syndromes. In: McMahon S.B., and Koltzenburg M. (Eds). Wall and Melzack's Textbook of Pain (2006), Elsevier, Churchill Livingstone 1011-1027
3. Bickel A., Kramer H.H., Hilz M.J., Birklein F., Neundorfer B., and Schmelz M. Assessment of the neurogenic flare reaction in small-fiber neuropathies. Neurology 59 (2002) 917-919
4. Blair S.J., Chinthagada M., Hoppenstehdt D., Kijowski R., and Fareed J. Role of neuropeptides in pathogenesis of reflex sympathetic dystrophy. Acta Orthop. Belg. 64 (1998) 448-451
5. Butler S., Nyman M., and Gordh T. Immobility in volunteers transiently produces signs and symptoms of complex regional pain syndrome. In: Devor M., Rowbotham M., and Wiesenfeld-Hallin Z. (Eds). Proceedings of the 9th World Congress on Pain. Progress in Pain Research and Management (2000), IASP press, Seattle 657-660
6. Butler S.H. Disuse and CRPS. In: Harden R.N., Baron R., and Janig W. (Eds). Complex Regional Pain Syndrome. Progress in Pain Research and Management (2001), IASP Press, Seattle 141-150
7. Caterina M.J. Transient receptor potential ion channels as participants in thermosensation and thermoregulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292 (2007) R64-R76
8. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
9. Daemen M., Kurvers H., Bullens P., Barendse G., Van Kleef M., and Van den Wildenberg F. Neurogenic inflammation and reflex sympathetic dystrophy (in vivo and in vitro assessment in an experimental model). Acta Orthop. Belg. 64 (1998) 441-447
10. Drummond P.D., Finch P.M., Edvinsson L., and Goadsby P.J. Plasma neuropeptide Y in the symptomatic limb of patients with causalgic pain. Clin. Auton. Res. 4 (1994) 113-116
11. Drummond P.D., Finch P.M., and Smythe G.A. Reflex sympathetic dystrophy: the significance of differing plasma catecholamine concentrations in affected and unaffected limbs. Brain 114 Pt 5 (1991) 2025-2036
12. Essex T.J., and Byrne P.O. A laser Doppler scanner for imaging blood flow in skin. J. Biomed. Eng. 13 (1991) 189-194
13. Gronblad M., Konttinen Y.T., Korkala O., Liesi P., Hukkanen M., and Polak J.M. Neuropeptides in synovium of patients with rheumatoid arthritis and osteoarthritis. J. Rheumatol. 15 (1988) 1807-1810
14. Guo T.Z., Offley S.C., Boyd E.A., Jacobs C.R., and Kingery W.S. Substance P signaling contributes to the vascular and nociceptive abnormalities observed in a tibial fracture rat model of complex regional pain syndrome type I. Pain 108 (2004) 95-107
15. Huang I.T., Lin W.M., Shun C.T., and Hsieh S.T. Influence of cutaneous nerves on keratinocyte proliferation and epidermal thickness in mice. Neuroscience 94 (1999) 965-973
16. Kinnman E., Nygards E.B., and Hansson P. Peripheral alpha-adrenoreceptors are involved in the development of capsaicin induced ongoing and stimulus evoked pain in humans. Pain 69 (1997) 79-85
17. Kurvers H.A., Jacobs M.J., Beuk R.J., van den Wildenberg F.A., Kitslaar P.J., Slaaf D.W., and Reneman R.S. Reflex sympathetic dystrophy: evolution of microcirculatory disturbances in time. Pain 60 (1995) 333-340
18. Lee W.S., and Sohn I.B. Substance P prolongs human hair growth in vitro. J. Dermatol. Sci. 33 (2003) 137-138
19. Leis S., Weber M., Isselmann A., Schmelz M., and Birklein F. Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome. Exp. Neurol. 183 (2003) 197-204
20. Lembeck F., and Holzer P. Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation. Naunyn Schmiedebergs Arch. Pharmacol. 310 (1979) 175-183
21. Levine J.D., and Alessandri-Haber N. TRP channels: targets for the relief of pain. Biochim. Biophys. Acta 1772 (2007) 989-1003
22. Lin Q., Li D., Xu X., Zou X., and Fang L. Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin. Mol. Pain 3 (2007) 30
23. Lin Q., Zou X., Fang L., and Willis W.D. Sympathetic modulation of acute cutaneous flare induced by intradermal injection of capsaicin in anesthetized rats. J. Neurophysiol. 89 (2003) 853-861
24. Lin Q., Zou X., Ren Y., Wang J., Fang L., and Willis W.D. Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin. Neuroscience 123 (2004) 337-347
25. Matthews J.N., Altman D.G., Campbell M.J., and Royston P. Analysis of serial measurements in medical research. BMJ 300 (1990) 230-235
26. McGovern U.B., Jones K.T., and Sharpe G.R. Intracellular calcium as a second messenger following growth stimulation of human keratinocytes. Br. J. Dermatol. 132 (1995) 892-896
27. Merskey H., and Bogduk N. Complex regional pain syndromes (CRPS). In: Merskey H., and Bogduk N. (Eds). Classification of Chronic Pain (1994), IASP press, Seattle 40-43
28. Meyer R.A., Ringkamp M., Campbell J.N., and Raja S.N. Peripheral mechanisms of cutaneous nociception. In: McMahon S.B., and Koltzenburg M. (Eds). Wall and Melzack's Textbook of Pain (2006), Elsevier, Churchill Livingstone 3-34
29. Oyen W.J., Arntz I.E., Claessens R.M., van der Meer J.W., Corstens F.H., and Goris R.J. Reflex sympathetic dystrophy of the hand: an excessive inflammatory response?. Pain 55 (1993) 151-157
30. Paus R., Heinzelmann T., Robicsek S., Czarnetzki B.M., and Maurer M. Substance P stimulates murine epidermal keratinocyte proliferation and dermal mast cell degranulation in situ. Arch. Dermatol. Res. 287 (1995) 500-502
31. Paus R., Heinzelmann T., Schultz K.D., Furkert J., Fechner K., and Czarnetzki B.M. Hair growth induction by substance P. Lab. Invest. 71 (1994) 134-140
32. Ravin N. New hair growth over fracture sites. N. Engl. J. Med. 323 (1990) 350
33. Schinkel C., Gaertner A., Zaspel J., Zedler S., Faist E., and Schuermann M. Inflammatory mediators are altered in the acute phase of posttraumatic complex regional pain syndrome. Clin. J. Pain 22 (2006) 235-239
34. Schwartzman R.J. Reflex sympathetic dystrophy and causalgia. Neurol. Clin. 10 (1992) 953-973
35. Stanton-Hicks M., Janig W., Hassenbusch S., Haddox J.D., Boas R., and Wilson P. Reflex sympathetic dystrophy: changing concepts and taxonomy. Pain 63 (1995) 127-133
36. Terkelsen A.J., Bach F.W., and Jensen T.S. Experimental forearm immobilization in humans induces cold and mechanical hyperalgesia. Anesthesiology 109 (2008) 297-307
37. Wasner G., Heckmann K., Maier C., and Baron R. Vascular abnormalities in acute reflex sympathetic dystrophy (CRPS I): complete inhibition of sympathetic nerve activity with recovery. Arch. Neurol. 56 (1999) 613-620
38. Wasner G., Schattschneider J., Heckmann K., Maier C., and Baron R. Vascular abnormalities in reflex sympathetic dystrophy (CRPS I): mechanisms and diagnostic value. Brain 124 (2001) 587-599
39. Weber M., Birklein F., Neundorfer B., and Schmelz M. Facilitated neurogenic inflammation in complex regional pain syndrome. Pain 91 (2001) 251-257
40. WMA Inc.,. World Medical Association Declaration of Helsinki. Recommendations guiding physicians in biomedical research involving human subjects. Cardiovasc. Res. 35 (1997) 2-3
41. Yonehara N., and Yoshimura M. Influence of painful chronic neuropathy on neurogenic inflammation. Pain 92 (2001) 259-265