Molecular characteristics and functional diversity of CLCA family members

Clinical and Experimental Pharmacology and Physiology

Volumn 27, Issue 11, 2000, Pages 901-905

  Pauli, Bendicht U ^a   Abdel Ghany, Mossaad ^a   Cheng, Hung Chi ^a   Gruber, Achim D ^a   Archibald, Heather A ^a   Elble, Randolph C ^a  

^a Animal Health Diagnostic Center   (United States)

Author keywords

Breast cancer; Cell adhesion; Lung endothelial cell adhesion molecule; Melanoma; Metastasis; Tumour suppression

Indexed keywords

CELL ADHESION MOLECULE; CHLORIDE CHANNEL; MEMBRANE PROTEIN; PROTEIN SUBUNIT;

ANIMAL CELL; BREAST CANCER; CONFERENCE PAPER; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; TUMOR SUPPRESSOR GENE;

ANIMALS; CALCIUM; CATTLE; CELL ADHESION; CHLORIDE CHANNELS; GENES, TUMOR SUPPRESSOR; HUMANS; MICE;

EID: 0033767665     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03358.x     Document Type: Conference Paper

References (34)

1. Cloning of an epithelial chloride channel from bovine trachea
2. Cloning and characterization of lung-endothelial cell adhesion molecule-1 suggest it is an endothelial chloride channel
3. Molecular and functional characterization of a calcium-sensitive chloride conductance protein from mouse lung
4. -channels
5. - channel from human lung, trachea and mammary gland
6. - channels
7. Mediation of lung metastasis of murine melanomas by a lung-specific endothelial adhesion molecule
8. Cloning and identification of the gene gob-5, which is expressed in intestinal goblet cells in mice
9. Induction of mouse Ca(2+)-sensitive chloride channel 2 gene during involution of mammary gland
10. Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea
11. Clustering of the human CLCA gene family on the short arm of chromosome 1 (1p22-31)
12. Characterization of a murine gene homologous to the bovine CaCC chloride channel
13. Assignment of the murine calcium-activated chloride channel genes mCLCA1 and mCLCA2 to chromosome 3 band H2-H3 with somatic cell hybrids
14. Generation of monoclonal antibodies directed against organ-specific endothelial cell surface determinants
15. The murine calcium-sensitive chloride channel (mCaCC) is widely expressed in secretory epithelia and other select tissues
16. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloproteinase inhibitors
17. Calmodulin regulates L-selectin adhesion molecule expression and function through a protease-dependent mechanism
18. An essential role for ectodomain shedding in mammalian development
19. Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
20. The ceal0 gene encodes a secreted member of the murine carcinoembryonic antigen family and is expressed in the placenta, gastrointestinal tract and bone marrow
21. Cea5, a structurally divergent member of the murine carcinoembryonic antigen gene family, is exclusively expressed during early placental development in trophoblast giant cells
22. Electrophysiological characteristics of the CLCA family of anion transport proteins
23. Endothelial cell adhesion molecules and pulmonary metastasis
24. Constitutive and inducible endothelial cell adhesion molecules in cancer metastasis
25. Correlation between the lung distribution patterns of Lu-ECAM-1 and melanoma experimental metastases
26. Blocking of lung endothelial cell adhesion molecule-1 (Lu-ECAM-1) inhibits murine melanoma lung metastases
27. Lu-ECAM-1-mediated adhesion of melanoma cells to endothelium under conditions of flow
28. - channel CLCA2
29. Allelic loss on chromosome 1p is associated with progression and lymph node metastasis of primary breast carcinoma
30. Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes
31. The role of calcium in apoptosis
32. Salmonella typhi uses CFTR to enter intestinal epithelial cells
33. - currents in cultured cells of the rat retinal pigment epithelium