메뉴 건너뛰기




Volumn 6, Issue SUPPL. 3, 2009, Pages 353-362

Mechanisms of penile fibrosis

Author keywords

Corporal veno occlusive dysfunction; Erectile dysfunction; Inducible nitric oxide synthase

Indexed keywords

COLLAGEN FIBER; CYCLIC GMP; NITRIC OXIDE; PIOGLITAZONE; SILDENAFIL; TADALAFIL; VARDENAFIL;

EID: 61849137692     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2008.01195.x     Document Type: Conference Paper
Times cited : (144)

References (68)
  • 1
    • 48249127629 scopus 로고    scopus 로고
    • From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
    • Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC 3rd. From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 2008; 57: 1439-45.
    • (2008) Diabetes , vol.57 , pp. 1439-1445
    • Qian, Y.1    Feldman, E.2    Pennathur, S.3    Kretzler, M.4    Brosius, F.C.5
  • 4
    • 21344457266 scopus 로고    scopus 로고
    • Mechanisms of disease: New insights into the cellular and molecular pathology of Peyronie's disease
    • Gonzalez-Cadavid NF, Rajfer J. Mechanisms of disease: New insights into the cellular and molecular pathology of Peyronie's disease. Nat Clin Pract Urol 2005; 2: 291-8.
    • (2005) Nat Clin Pract Urol , vol.2 , pp. 291-298
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 5
    • 35648946349 scopus 로고    scopus 로고
    • Priapism: Current principles and practice
    • Burnett AL, Bivalacqua TJ. Priapism: Current principles and practice. Urol Clin North Am 2007; 34: 631-42.
    • (2007) Urol Clin North Am , vol.34 , pp. 631-642
    • Burnett, A.L.1    Bivalacqua, T.J.2
  • 6
    • 17144364721 scopus 로고    scopus 로고
    • Histological alterations in cavernous tissue after radical prostatectomy
    • Iacono F, Giannella R, Somma P, Manno G, Fusco F, Mirone V. Histological alterations in cavernous tissue after radical prostatectomy. J Urol 2005; 173: 1673-6.
    • (2005) J Urol , vol.173 , pp. 1673-1676
    • Iacono, F.1    Giannella, R.2    Somma, P.3    Manno, G.4    Fusco, F.5    Mirone, V.6
  • 7
    • 0347129566 scopus 로고    scopus 로고
    • Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy
    • Schwartz EJ, Wong P, Graydon RJ. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. J Urol 2004; 171: 771-4.
    • (2004) J Urol , vol.171 , pp. 771-774
    • Schwartz, E.J.1    Wong, P.2    Graydon, R.J.3
  • 8
    • 38149131204 scopus 로고    scopus 로고
    • Rationale for phosphodiesterase 5 inhibitor use post-radical prostatectomy: Experimental and clinical review
    • Rambhatla A, Kovanecz I, Ferrini M, Gonzalez-Cadavid NF, Rajfer J. Rationale for phosphodiesterase 5 inhibitor use post-radical prostatectomy: Experimental and clinical review. Int J Impot Res 2008; 20: 30-4.
    • (2008) Int J Impot Res , vol.20 , pp. 30-34
    • Rambhatla, A.1    Kovanecz, I.2    Ferrini, M.3    Gonzalez-Cadavid, N.F.4    Rajfer, J.5
  • 9
    • 34247534567 scopus 로고    scopus 로고
    • Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis
    • Ferrini MG, Kovanecz I, Sanchez S, Vernet D, Davila HH, Rajfer J, Gonzalez-Cadavid NF. Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis. Biol Reprod 2007; 76: 915-23.
    • (2007) Biol Reprod , vol.76 , pp. 915-923
    • Ferrini, M.G.1    Kovanecz, I.2    Sanchez, S.3    Vernet, D.4    Davila, H.H.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 10
    • 1342281658 scopus 로고    scopus 로고
    • Aging-related induction of inducible nitric oxide synthase (iNOS) is vasculo-protective in the arterial media
    • Ferrini MG, Davila H, Valente EG, Gonzalez-Cadavid NF, Rajfer J. Aging-related induction of inducible nitric oxide synthase (iNOS) is vasculo-protective in the arterial media. Cardiovasc Res 2004; 61: 796-805.
    • (2004) Cardiovasc Res , vol.61 , pp. 796-805
    • Ferrini, M.G.1    Davila, H.2    Valente, E.G.3    Gonzalez-Cadavid, N.F.4    Rajfer, J.5
  • 11
    • 0038310955 scopus 로고    scopus 로고
    • Fibrin induction of a Peyronie's-like plaque in the rat penile tunica albuginea. A new model for Peyronie's disease
    • Davila H, Ferrini M, Rajfer J, Gonzalez-Cadavid NF. Fibrin induction of a Peyronie's-like plaque in the rat penile tunica albuginea. A new model for Peyronie's disease. Br J Urol 2003; 91: 830-8.
    • (2003) Br J Urol , vol.91 , pp. 830-838
    • Davila, H.1    Ferrini, M.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 12
    • 0031060222 scopus 로고    scopus 로고
    • Fibrin deposition in Peyronie's disease plaque
    • Somers KD, Dawson DM. Fibrin deposition in Peyronie's disease plaque. J Urol 1997; 157: 311-5.
    • (1997) J Urol , vol.157 , pp. 311-315
    • Somers, K.D.1    Dawson, D.M.2
  • 14
    • 0037362915 scopus 로고    scopus 로고
    • Penile weight and cell subtype specific changes in a post-radical prostatectomy model of erectile dysfunction
    • User HM, Hairston JH, Zelner DJ, McKenna KE, McVary KT. Penile weight and cell subtype specific changes in a post-radical prostatectomy model of erectile dysfunction. J Urol 2003; 169: 1175-9.
    • (2003) J Urol , vol.169 , pp. 1175-1179
    • User, H.M.1    Hairston, J.H.2    Zelner, D.J.3    McKenna, K.E.4    McVary, K.T.5
  • 16
    • 33746808198 scopus 로고    scopus 로고
    • Long-term continuous treatment with vardenafil prevents fibrosis and preserves smooth muscle content in the rat corpora cavernosa after bilateral cavernosal nerve transaction
    • Ferrini MG, Davila H, Kovanecz I, Sanchez S, Gonzalez-Cadavid NF, Rajfer J. Long-term continuous treatment with vardenafil prevents fibrosis and preserves smooth muscle content in the rat corpora cavernosa after bilateral cavernosal nerve transaction. Urology 2006; 68: 429-35.
    • (2006) Urology , vol.68 , pp. 429-435
    • Ferrini, M.G.1    Davila, H.2    Kovanecz, I.3    Sanchez, S.4    Gonzalez-Cadavid, N.F.5    Rajfer, J.6
  • 17
    • 34548453726 scopus 로고    scopus 로고
    • Long term sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats
    • Kovanecz I, Rambhatla A, Ferrini MG, Vernet D, Sanchez S, Rajfer J, Gonzalez-Cadavid NF. Long term sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats. Int J Impot Res 2007; 100: 867-74.
    • (2007) Int J Impot Res , vol.100 , pp. 867-874
    • Kovanecz, I.1    Rambhatla, A.2    Ferrini, M.G.3    Vernet, D.4    Sanchez, S.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 18
    • 37349061006 scopus 로고    scopus 로고
    • Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction (CVOD) that occurs following cavernosal nerve resection in the rat
    • Kovanecz I, Rambhatla A, Ferrini MG, Vernet D, Sanchez S, Rajfer J, Gonzalez-Cadavid NF. Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction (CVOD) that occurs following cavernosal nerve resection in the rat. BJU Int 2008; 101: 203-10.
    • (2008) BJU Int , vol.101 , pp. 203-210
    • Kovanecz, I.1    Rambhatla, A.2    Ferrini, M.G.3    Vernet, D.4    Sanchez, S.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 19
    • 85031366019 scopus 로고    scopus 로고
    • Fibrosis and loss of smooth muscle in the corpora cavernosa precede corporal veno-occlusive dysfunction (CVOD) induced by experimental cavernosal nerve damage in the rat
    • (in press)
    • Ferrini MG, Kovanecz I, Sanchez S, Vernet D, Umeh C, Rajfer J, Gonzalez-Cadavid NF. Fibrosis and loss of smooth muscle in the corpora cavernosa precede corporal veno-occlusive dysfunction (CVOD) induced by experimental cavernosal nerve damage in the rat. J Sex Med 2008 (in press).
    • (2008) J Sex Med
    • Ferrini, M.G.1    Kovanecz, I.2    Sanchez, S.3    Vernet, D.4    Umeh, C.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 21
    • 0035110585 scopus 로고    scopus 로고
    • Aging-related expression of inducible nitric oxide synthase (iNOS) and markers of tissue damage in the rat penis
    • Ferrini M, Magee TR, Vernet D, Rajfer J, Gonzalez-Cadavid NF. Aging-related expression of inducible nitric oxide synthase (iNOS) and markers of tissue damage in the rat penis. Biol Reprod 2001; 64: 974-82.
    • (2001) Biol Reprod , vol.64 , pp. 974-982
    • Ferrini, M.1    Magee, T.R.2    Vernet, D.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 22
    • 34548453726 scopus 로고    scopus 로고
    • Pioglitazone ameliorates penile corpora veno-occlusive dysfunction (CVOD) in the aged rat
    • Kovanecz I, Ferrini MG, Davila HH, Rajfer J, Gonzalez-Cadavid NF. Pioglitazone ameliorates penile corpora veno-occlusive dysfunction (CVOD) in the aged rat. BJU Int 2007; 100: 867-74.
    • (2007) BJU Int , vol.100 , pp. 867-874
    • Kovanecz, I.1    Ferrini, M.G.2    Davila, H.H.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 23
    • 33745088146 scopus 로고    scopus 로고
    • Pioglitazone prevents corporal veno-occlusive dysfunction (CVOD) in a rat model of type 2 diabetes mellitus
    • Kovanecz I, Ferrini MG, Vernet D, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. Pioglitazone prevents corporal veno-occlusive dysfunction (CVOD) in a rat model of type 2 diabetes mellitus. BJU Int 2006; 98: 116-24.
    • (2006) BJU Int , vol.98 , pp. 116-124
    • Kovanecz, I.1    Ferrini, M.G.2    Vernet, D.3    Nolazco, G.4    Rajfer, J.5    Gonzalez-Cadavid, N.F.6
  • 25
    • 41849111684 scopus 로고    scopus 로고
    • Effect of muscle derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat
    • Nolazco G, Kovanecz I, Vernet D, Ferrini M, Gelfand B, Tsao J, Magee T, Rajfer J, Gonzalez-Cadavid NF. Effect of muscle derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat. BJU Int 2008; 101: 1156-64.
    • (2008) BJU Int , vol.101 , pp. 1156-1164
    • Nolazco, G.1    Kovanecz, I.2    Vernet, D.3    Ferrini, M.4    Gelfand, B.5    Tsao, J.6    Magee, T.7    Rajfer, J.8    Gonzalez-Cadavid, N.F.9
  • 26
    • 27944480642 scopus 로고    scopus 로고
    • Detrimental effect of cigarette smoking on erectile dysfunction in the rat is contingent to diabetes as co-morbidity
    • (#1420)
    • Dávila HH, Ferrini MG, Magee TR, Rajfer J, González-Cadavid NF. Detrimental effect of cigarette smoking on erectile dysfunction in the rat is contingent to diabetes as co-morbidity. J Urol 2004; 171: 374 (#1420).
    • (2004) J Urol , vol.171 , pp. 374
    • Dávila, H.H.1    Ferrini, M.G.2    Magee, T.R.3    Rajfer, J.4    González-Cadavid, N.F.5
  • 27
    • 0031805559 scopus 로고    scopus 로고
    • Evidence based assessment of erectile dysfunction
    • discussion S77-9
    • Broderick GA. Evidence based assessment of erectile dysfunction. Int J Impot Res 1998; 10: (2 suppl): S64-73; discussion S77-9.
    • (1998) Int J Impot Res , vol.10 , Issue.2 SUPPL.
    • Broderick, G.A.1
  • 28
    • 9644259802 scopus 로고    scopus 로고
    • Corporal veno-occlusive dysfunction in the aging rat. Evaluation by cavernosometry and cavernosography
    • Davila HH, Rajfer J, Gonzalez-Cadavid NF. Corporal veno-occlusive dysfunction in the aging rat. Evaluation by cavernosometry and cavernosography. Urology 2004; 64: 1261-6.
    • (2004) Urology , vol.64 , pp. 1261-1266
    • Davila, H.H.1    Rajfer, J.2    Gonzalez-Cadavid, N.F.3
  • 29
    • 49849089716 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Insights into pathogenesis, diagnostic challenges, and therapeutic options
    • Aneja A, Tang WH, Bansilal S, Garcia MJ, Farkouh ME. Diabetic cardiomyopathy: Insights into pathogenesis, diagnostic challenges, and therapeutic options. Am J Med 2008; 121: 748-57.
    • (2008) Am J Med , vol.121 , pp. 748-757
    • Aneja, A.1    Tang, W.H.2    Bansilal, S.3    Garcia, M.J.4    Farkouh, M.E.5
  • 30
    • 34548766577 scopus 로고    scopus 로고
    • Oxidative stress and cardiac repair/remodeling following infarction
    • Sun Y. Oxidative stress and cardiac repair/remodeling following infarction. Am J Med Sci 2007; 334: 197-205.
    • (2007) Am J Med Sci , vol.334 , pp. 197-205
    • Sun, Y.1
  • 31
    • 48949096061 scopus 로고    scopus 로고
    • Hepatic fibrogenesis in response to chronic liver injury: Novel insights on the role of cell-to-cell interaction and transition
    • Svegliati-Baroni G, De Minicis S, Marzioni M. Hepatic fibrogenesis in response to chronic liver injury: Novel insights on the role of cell-to-cell interaction and transition. Liver Int 2008; 28: 1052-64.
    • (2008) Liver Int , vol.28 , pp. 1052-1064
    • Svegliati-Baroni, G.1    De Minicis, S.2    Marzioni, M.3
  • 32
    • 49649098812 scopus 로고    scopus 로고
    • Pharmacotherapy in patients with idiopathic pulmonary fibrosis
    • Nagai S, Handa T, Kim D. Pharmacotherapy in patients with idiopathic pulmonary fibrosis. Expert Opin Pharmacother 2008; 9: 1909-25.
    • (2008) Expert Opin Pharmacother , vol.9 , pp. 1909-1925
    • Nagai, S.1    Handa, T.2    Kim, D.3
  • 33
    • 33846573898 scopus 로고    scopus 로고
    • Fibroblast differentiation in wound healing and fibrosis
    • Darby IA, Hewitson TD. Fibroblast differentiation in wound healing and fibrosis. Int Rev Cytol 2007; 257: 143-79.
    • (2007) Int Rev Cytol , vol.257 , pp. 143-179
    • Darby, I.A.1    Hewitson, T.D.2
  • 34
    • 85031360627 scopus 로고    scopus 로고
    • Experimental models for Peyronie's disease. Implications for therapy
    • (in press)
    • Gonzalez-Cadavid NF, Rajfer J. Experimental models for Peyronie's disease. Implications for therapy. J Sex Med 2008 (in press).
    • (2008) J Sex Med
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 35
    • 3042697005 scopus 로고    scopus 로고
    • Chromosomal instability is demonstrated by fibroblasts derived from the tunica of men with Peyronie's disease
    • Mulhall JP, Nicholson B, Pierpaoli S, Lubrano T, Shankey TV. Chromosomal instability is demonstrated by fibroblasts derived from the tunica of men with Peyronie's disease. Int J Impot Res 2004; 16: 288-93.
    • (2004) Int J Impot Res , vol.16 , pp. 288-293
    • Mulhall, J.P.1    Nicholson, B.2    Pierpaoli, S.3    Lubrano, T.4    Shankey, T.V.5
  • 36
    • 0035675320 scopus 로고    scopus 로고
    • Perturbation of cell cycle regulators in Peyronie's disease
    • Mulhall JP, Branch J, Lubrano T, Shankey TV. Perturbation of cell cycle regulators in Peyronie's disease. Int J Impot Res 2001; 13 (5 suppl): S21-8.
    • (2001) Int J Impot Res , vol.13 , Issue.5 SUPPL.
    • Mulhall, J.P.1    Branch, J.2    Lubrano, T.3    Shankey, T.V.4
  • 37
    • 0034040920 scopus 로고    scopus 로고
    • A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression
    • Bivalacqua TJ, Diner EK, Novak TE, Vohra Y, Sikka SC, Champion HC, Kadowitz PJ, Hellstrom WJ. A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression. J Urol 2000; 163: 1992-8.
    • (2000) J Urol , vol.163 , pp. 1992-1998
    • Bivalacqua, T.J.1    Diner, E.K.2    Novak, T.E.3    Vohra, Y.4    Sikka, S.C.5    Champion, H.C.6    Kadowitz, P.J.7    Hellstrom, W.J.8
  • 39
    • 0036434536 scopus 로고    scopus 로고
    • Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's fibrotic plaque and in its rat model
    • Vernet D, Ferrini MG, Valente E, Magee TR, Bou-Gharios G, Rajfer J, Gonzalez-Cadavid NF. Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's fibrotic plaque and in its rat model. Nitric Oxide 2002; 7: 262-76.
    • (2002) Nitric Oxide , vol.7 , pp. 262-276
    • Vernet, D.1    Ferrini, M.G.2    Valente, E.3    Magee, T.R.4    Bou-Gharios, G.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 40
    • 17144381703 scopus 로고    scopus 로고
    • Peyronie's disease is associated with an increase of plasminogen activator inhibitor-1 (PAI-1) at the RNA and protein levels
    • Davila H, Magee TR, Rajfer J, Gonzalez-Cadavid NF. Peyronie's disease is associated with an increase of plasminogen activator inhibitor-1 (PAI-1) at the RNA and protein levels. Urology 2005; 65: 645-8.
    • (2005) Urology , vol.65 , pp. 645-648
    • Davila, H.1    Magee, T.R.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 41
    • 23744500105 scopus 로고    scopus 로고
    • Molecular and cellular aspects of the pathophysiology of Peyronie's disease
    • Gonzalez-Cadavid NF, Rajfer J. Molecular and cellular aspects of the pathophysiology of Peyronie's disease. Drug Discov Today Dis Mech 2004; 1: 99-106.
    • (2004) Drug Discov Today Dis Mech , vol.1 , pp. 99-106
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 42
    • 6344243407 scopus 로고    scopus 로고
    • Gene therapy with the inducible nitric oxide synthase (iNOS) cDNA regresses the fibrotic plaque in an animal model of Peyronie's disease
    • Davila HH, Magee TR, Rajfer J, Gonzalez-Cadavid NF. Gene therapy with the inducible nitric oxide synthase (iNOS) cDNA regresses the fibrotic plaque in an animal model of Peyronie's disease. Biol Reprod 2004; 71: 1568-77.
    • (2004) Biol Reprod , vol.71 , pp. 1568-1577
    • Davila, H.H.1    Magee, T.R.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 43
    • 28144438892 scopus 로고    scopus 로고
    • Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells. Implications for Peyronie's disease
    • Vernet D, Qian A, Nolazco G, Cantini L, Magee TR, Ferrini MG, Rajfer J, Gonzalez-Cadavid NF. Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells. Implications for Peyronie's disease. Biol Reprod 2005; 73: 1199-210.
    • (2005) Biol Reprod , vol.73 , pp. 1199-1210
    • Vernet, D.1    Qian, A.2    Nolazco, G.3    Cantini, L.4    Magee, T.R.5    Ferrini, M.G.6    Rajfer, J.7    Gonzalez-Cadavid, N.F.8
  • 45
    • 4143098278 scopus 로고    scopus 로고
    • Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture
    • Qian A, Meals R, Rajfer J, Gonzalez-Cadavid NF. Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture. Urology 2004; 64: 399-404.
    • (2004) Urology , vol.64 , pp. 399-404
    • Qian, A.1    Meals, R.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 46
    • 1542351289 scopus 로고    scopus 로고
    • L-arginine and PDE inhibitors counteract fibrosis in Peyronie's plaque and related fibroblast cultures
    • Valente EG, Vernet D, Ferrini MG, Qian A, Rajfer J, Gonzalez-Cadavid NF. L-arginine and PDE inhibitors counteract fibrosis in Peyronie's plaque and related fibroblast cultures. Nitric Oxide 2003; 9: 229-44.
    • (2003) Nitric Oxide , vol.9 , pp. 229-244
    • Valente, E.G.1    Vernet, D.2    Ferrini, M.G.3    Qian, A.4    Rajfer, J.5    Gonzalez-Cadavid, N.F.6
  • 47
    • 33644991137 scopus 로고    scopus 로고
    • Effects of long-term treatment with vardenafil on the development of the fibrotic plaque in a rat model of Peyronie's disease
    • Ferrini MG, Kovanecz I, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. Effects of long-term treatment with vardenafil on the development of the fibrotic plaque in a rat model of Peyronie's disease. BJU Int 2006; 97: 625-33.
    • (2006) BJU Int , vol.97 , pp. 625-633
    • Ferrini, M.G.1    Kovanecz, I.2    Nolazco, G.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 48
    • 33645744143 scopus 로고    scopus 로고
    • Long-term continuous incubation with high doses of tadalafil does not up-regulate the levels of phosphodiesterase 5 (PDE5) in cultures of human penile smooth muscle cells
    • discussion 94-5
    • Vernet D, Magee TR, Qian A, Rajfer J, Gonzalez-Cadavid NF. Long-term continuous incubation with high doses of tadalafil does not up-regulate the levels of phosphodiesterase 5 (PDE5) in cultures of human penile smooth muscle cells. J Sex Med 2006; 3: 84-94, discussion 94-5.
    • (2006) J Sex Med , vol.3 , pp. 84-94
    • Vernet, D.1    Magee, T.R.2    Qian, A.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 50
    • 33748902582 scopus 로고    scopus 로고
    • Increased vaginal oxidative stress, apoptosis, and inducible nitric oxide synthase in a diabetic rat model: Implications for vaginal fibrosis
    • Ferrini MG, Nolazco G, Vernet D, Gonzalez-Cadavid NF, Berman J. Increased vaginal oxidative stress, apoptosis, and inducible nitric oxide synthase in a diabetic rat model: Implications for vaginal fibrosis. Fertil Steril 2006; 86: 1152-63.
    • (2006) Fertil Steril , vol.86 , pp. 1152-1163
    • Ferrini, M.G.1    Nolazco, G.2    Vernet, D.3    Gonzalez-Cadavid, N.F.4    Berman, J.5
  • 51
    • 27944448794 scopus 로고    scopus 로고
    • The pleiotropic effects of inducible nitric oxide synthase on the physiology and pathology of penile erection
    • Gonzalez-Cadavid NF, Rajfer J. The pleiotropic effects of inducible nitric oxide synthase on the physiology and pathology of penile erection. Curr Pharm Des 2005; 11: 4041-6.
    • (2005) Curr Pharm Des , vol.11 , pp. 4041-4046
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 52
    • 37349114299 scopus 로고    scopus 로고
    • Age-independent penile fibrosis in the inducible nitric oxide synthase knock-out (iNOS ko) mouse supports the antifibrotic role of iNOS
    • New York, NY
    • Ferrini M, Sanchez S, Vernet D, Kovanecz I, Rajfer J, Gonzalez-Cadavid NF. Age-independent penile fibrosis in the inducible nitric oxide synthase knock-out (iNOS ko) mouse supports the antifibrotic role of iNOS. Soc Sex Medcin Nort Am Meeting, New York, NY, 2006.
    • (2006) Soc Sex Medcin Nort Am Meeting
    • Ferrini, M.1    Sanchez, S.2    Vernet, D.3    Kovanecz, I.4    Rajfer, J.5    Gonzalez-Cadavid, N.F.6
  • 56
    • 48749121252 scopus 로고    scopus 로고
    • Intracavernous growth differentiation factor-5 therapy enhances the recovery of erectile function in a rat model of cavernous nerve injury
    • Fandel TM, Bella AJ, Lin G, Tantiwongse K, Lin CS, Pohl J, Lue TF. Intracavernous growth differentiation factor-5 therapy enhances the recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 2008; 5: 1866-75.
    • (2008) J Sex Med , vol.5 , pp. 1866-1875
    • Fandel, T.M.1    Bella, A.J.2    Lin, G.3    Tantiwongse, K.4    Lin, C.S.5    Pohl, J.6    Lue, T.F.7
  • 58
    • 44949145372 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 restores erectile function in aged rats: Modulation the integrity of smooth muscle and nitric oxide-cyclic guanosine monophosphate signaling activity
    • Pu XY, Wang XH, Gao WC, Yang ZH, Li SL, Wang HP, Wu YL. Insulin-like growth factor-1 restores erectile function in aged rats: Modulation the integrity of smooth muscle and nitric oxide-cyclic guanosine monophosphate signaling activity. J Sex Med 2008; 5: 1345-54.
    • (2008) J Sex Med , vol.5 , pp. 1345-1354
    • Pu, X.Y.1    Wang, X.H.2    Gao, W.C.3    Yang, Z.H.4    Li, S.L.5    Wang, H.P.6    Wu, Y.L.7
  • 59
    • 34347397618 scopus 로고    scopus 로고
    • Potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells
    • Song YS, Lee HJ, Park IH, Kim WK, Ku JH, Kim SU. Potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells. Int J Impot Res 2007; 19: 378-85.
    • (2007) Int J Impot Res , vol.19 , pp. 378-385
    • Song, Y.S.1    Lee, H.J.2    Park, I.H.3    Kim, W.K.4    Ku, J.H.5    Kim, S.U.6
  • 61
  • 62
    • 39749159662 scopus 로고    scopus 로고
    • Myostatin promotes a fibrotic phenotypic switch in multipotent C3h 10T1/ 2 cells without affecting their differentiation into myofibroblasts
    • Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin promotes a fibrotic phenotypic switch in multipotent C3h 10T1/ 2 cells without affecting their differentiation into myofibroblasts. J Endocrinol 2008; 196: 235-49.
    • (2008) J Endocrinol , vol.196 , pp. 235-249
    • Artaza, J.N.1    Singh, R.2    Ferrini, M.G.3    Braga, M.4    Tsao, J.5    Gonzalez-Cadavid, N.F.6
  • 64
    • 53549106900 scopus 로고    scopus 로고
    • Role of increased penile expression of transforming growth factor-beta1 and activation of the smad signaling pathway in erectile dysfunction in streptozotocin-induced diabetic rats
    • [Epub ahead of print]
    • Zhang LW, Piao S, Choi MJ, Shin HY, Jin HR, Kim WJ, Song SU, Han JY, Park SH, Mamura M, Kim SJ, Ryu JK, Suh JK. Role of increased penile expression of transforming growth factor-beta1 and activation of the smad signaling pathway in erectile dysfunction in streptozotocin-induced diabetic rats. J Sex Med 2008 [Epub ahead of print].
    • (2008) J Sex Med
    • Zhang, L.W.1    Piao, S.2    Choi, M.J.3    Shin, H.Y.4    Jin, H.R.5    Kim, W.J.6    Song, S.U.7    Han, J.Y.8    Park, S.H.9    Mamura, M.10    Kim, S.J.11    Ryu, J.K.12    Suh, J.K.13
  • 66
    • 85031356272 scopus 로고    scopus 로고
    • Skeletal muscle-derived stem cells (MDSC) seeded on small intestinal submucosal (SIS) scaffolds stimulate vaginal repair in the rat
    • (A1369)
    • Ho MH, Heydarkhan S, Vernet D, Kovanecz I, Ferrini MG, Bhatia NN, Gonzalez-Cadavid NF. Skeletal muscle-derived stem cells (MDSC) seeded on small intestinal submucosal (SIS) scaffolds stimulate vaginal repair in the rat. J Urol 2008; 179: 46B. (A1369).
    • (2008) J Urol , vol.179
    • Ho, M.H.1    Heydarkhan, S.2    Vernet, D.3    Kovanecz, I.4    Ferrini, M.G.5    Bhatia, N.N.6    Gonzalez-Cadavid, N.F.7
  • 68
    • 54949137626 scopus 로고    scopus 로고
    • Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity
    • [Epub ahead of print]
    • Ratajczak MZ, Zuba-Surma EK, Shin DM, Ratajczak J, Kucia M. Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity. Exp Gerontol 2008 [Epub ahead of print].
    • (2008) Exp Gerontol
    • Ratajczak, M.Z.1    Zuba-Surma, E.K.2    Shin, D.M.3    Ratajczak, J.4    Kucia, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.