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Volumn 72, Issue 7, 2009, Pages 586-587

Brain atrophy as an outcome measure for multiple sclerosis clinical trials: A "no-brainer"?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; INTERFERON BETA SERINE; NEUROPROTECTIVE AGENT;

EID: 61849106994     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000342478.46908.79     Document Type: Editorial
Times cited : (4)

References (9)
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    • 0033663894 scopus 로고    scopus 로고
    • Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients
    • Bjartmar C, Kidd G, Mork S, Rudick R, Trapp BD. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann Neurol 2000;48:893-901.
    • (2000) Ann Neurol , vol.48 , pp. 893-901
    • Bjartmar, C.1    Kidd, G.2    Mork, S.3    Rudick, R.4    Trapp, B.D.5
  • 3
    • 54849431166 scopus 로고    scopus 로고
    • Gray matter atrophy in multiple sclerosis: A longitudinal study
    • Fisher E, Lee JC, Nakamura K, Rudick RA. Gray matter atrophy in multiple sclerosis: a longitudinal study. Ann Neurol 2008;64:255-265.
    • (2008) Ann Neurol , vol.64 , pp. 255-265
    • Fisher, E.1    Lee, J.C.2    Nakamura, K.3    Rudick, R.A.4
  • 4
    • 30844464790 scopus 로고    scopus 로고
    • The measurement and clinical relevance of brain atrophy in multiple sclerosis
    • Bermel RA, Bakshi R. The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol 2006;5:158-170.
    • (2006) Lancet Neurol , vol.5 , pp. 158-170
    • Bermel, R.A.1    Bakshi, R.2
  • 5
    • 61849095259 scopus 로고    scopus 로고
    • Sample sizes for brain atrophy outcomes in trials for secondary progressive multiple sclerosis
    • Altmann DR, Jasperse B, Barkhof F, et al. Sample sizes for brain atrophy outcomes in trials for secondary progressive multiple sclerosis. Neurology 2009:72:595-601.
    • (2009) Neurology , vol.72 , pp. 595-601
    • Altmann, D.R.1    Jasperse, B.2    Barkhof, F.3
  • 6
    • 0033759398 scopus 로고    scopus 로고
    • The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis: European Study Group on Interferon beta-1b in secondarypro-gressive multiple sclerosis
    • Molyneux PD, Kappos L, Polman C, et al. The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis: European Study Group on Interferon beta-1b in secondarypro-gressive multiple sclerosis. Brain 2000;123:2256-2263.
    • (2000) Brain , vol.123 , pp. 2256-2263
    • Molyneux, P.D.1    Kappos, L.2    Polman, C.3
  • 8
    • 0033544320 scopus 로고    scopus 로고
    • Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS: Multiple Sclerosis Collaborative Research Group
    • Rudick RA, Fisher E, Lee JC, Simon J, Jacobs L. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS: Multiple Sclerosis Collaborative Research Group. Neurology 1999:53:1698-1704.
    • (1999) Neurology , vol.53 , pp. 1698-1704
    • Rudick, R.A.1    Fisher, E.2    Lee, J.C.3    Simon, J.4    Jacobs, L.5
  • 9
    • 0346754904 scopus 로고    scopus 로고
    • Atrophy is detectable within a 3-month period in untreated patients with active relapsing remitting multiple sclerosis
    • Hardmeier M, Wagenpfeil S, Freitag P, et al. Atrophy is detectable within a 3-month period in untreated patients with active relapsing remitting multiple sclerosis. Arch Neurol 2003:60:1736-1739.
    • (2003) Arch Neurol , vol.60 , pp. 1736-1739
    • Hardmeier, M.1    Wagenpfeil, S.2    Freitag, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.