B-CLL kicks it up a notch

Blood

Volumn 113, Issue 4, 2009, Pages 765-766

  Osborne, Barbara A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR;

APOPTOSIS; B CELL CHRONIC LYMPHOCYTIC LEUKEMIA; B CELL LEUKEMIA; CARCINOGENESIS; CELL CYCLE ARREST; CELL FATE; CELL SURVIVAL; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; LYMPHATIC LEUKEMIA; NOTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 61849097742     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-10-182998     Document Type: Note

References (4)

1. Ellisen LW, Bird J, West DC, et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations inTlymphoblastic neoplasms. Cell. 1991;66:649-661.
2. Weng AP, Ferrando AA, Lee W, et al. Activating mutations of NOTCH1 in humanTcell acute lymphoblastic leukemia. Science. 2004;306:269-271.
3. Bray SJ. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol. 2006;7678-7689.
4. Rizzo P, Osipo C, Foreman K, et al. Rational targeting of Notch signaling in cancer. Oncogene. 2008;27:5124-5131.