Insulin withdrawal-induced cell death in adult hippocampal neural stem cells as a model of autophagic cell death

Autophagy

Volumn 5, Issue 2, 2009, Pages 277-279

  Baek, Seung Hoon ^a   Kim, Eun Kyoung ^a,d   Goudreau, John L ^a,b,c   Lookingland, Keith J ^b,c   Kim, Seong Who ^e   Yu, Seong Woon ^a,b  

^a East Lansing   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d Michigan State University   (United States)

^e University of Ulsan College of Medicine   (South Korea)

Author keywords

Apoptosis; Autophagy; Cell death; Hippocampal neural stem cells; Insulin withdrawal

Indexed keywords

BECLIN 1; INSULIN; MEMBRANE PROTEIN; MEMBRANE PROTEIN ATG7; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; RAPAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL DEATH; CELL VACUOLE; HIPPOCAMPUS; HUMAN; INSULIN DEFICIENCY; NEURAL STEM CELL;

EID: 61649122814     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.2.7641     Document Type: Article

References (21)

1. Schweichel JU, Merker HJ. The morphology of various types of cell death in prenatal tissues. Teratology 1973; 7:253-66.
2. Clarke PG. Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol (Berl) 1990; 181:195-213.
3. Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L, et al. Cell death modalities: classification and pathophysiological implications. Cell Death Differ 2007; 14:1237-43.
4. Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science 2004; 306:990-5.
5. Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004; 23:2891-906.
6. Meijer AJ, Codogno P. Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol 2004; 36:2445-62.
7. Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005; 6:505-10.
8. Scarlatti F, Granata R, Meijer AJ, Codogno P. Does autophagy have a license to kill mammalian cells? Cell Death Differ 2008.
9. Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6:1221-8.
10. Arico S, Petiot A, Bauvy C, Dubbelhuis PF, Meijer AJ, Codogno P, et al. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 2001; 276:35243-6.
11. Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304:1500-2.
12. Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 2005; 115:2679-88.
13. Yu SW, Baek SH, Brennan RT, Bradley CJ, Park SK, Lee YS, et al. Autophagic death of adult hippocampal neural stem cells following insulin withdrawal. Stem Cells 2008; 26:2602-10.
14. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720-8.
15. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151-75.
16. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004; 116:205-19.
17. Yuan J. Divergence from a dedicated cellular suicide mechanism: exploring the evolution of cell death. Mol Cell 2006; 23:1-12.
18. Kroemer G, Martin SJ. Caspase-independent cell death. Nat Med 2005; 11:725-30.
19. Graeber MB, Moran LB. Mechanisms of cell death in neurodegenerative diseases: fashion, fiction and facts. Brain Pathol 2002; 12:385-90.
20. Kanazawa I. How do neurons die in neurodegenerative diseases? Trends Mol Med 2001; 7:339-44.
21. Yuan J, Lipinski M, Degterev A. Diversity in the mechanisms of neuronal cell death. Neuron 2003; 40:401-13.