Endothelin-1 induced MCAO: Dose dependency of cerebral blood flow

Journal of Neuroscience Methods

Volumn 179, Issue 1, 2009, Pages 22-28

  Nikolova, Simona ^a,b   Moyanova, Slavianka ^c   Hughes, Sarah ^a   Bellyou Camilleri, Miranda ^a   Lee, Ting Yim ^a,d   Bartha, Robert ^a,d  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

^c BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cerebral blood flow; Endothelin; Histology; Ischemia; Isoflurane; Rat; Stroke model

Indexed keywords

ENDOTHELIN 1; ISOFLURANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; DISEASE MODEL; DOSE RESPONSE; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PERFUSION WEIGHTED IMAGING; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX;

ANALYSIS OF VARIANCE; ANIMALS; CEREBROVASCULAR CIRCULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICROINJECTIONS; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SOMATOSENSORY CORTEX; TOMOGRAPHY, X-RAY COMPUTED;

EID: 61649084180     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.01.009     Document Type: Article

References (42)

1. Beauchamp N.J.J., and Bryan R.N. Acute cerebral ischemic infarction: a pathophysiologic review and radiologic perspective. Am J Roentgenol 171 (1998) 73-84
2. Bederson J.B., Pitts L.H., Germano S.M., Nishimura M.C., Davis L.R., and Bartkowski H.M. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17 (1986) 1304-1307
3. Biernaskie J., Corbett D., Peeling J., Wells J., and Lei H. A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats. Magn Reson Med 46 (2001) 827-830
4. Bogaert L., Scheller D., Moonen J., Sarre S., Smolders I., Ebinger G., et al. Neurochemical changes and laser doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia. Brain Res 887 (2000) 266-275
5. Callaway J.K., Knight M.J., Watkins D.J., Beart P.M., Jarrott B., and Delaney P.M. A novel, rapid, computerized method for quantitation of neuronal damage in a rat model of stroke. J Neurosci Methods 102 (2000) 53-60
6. Cenic A., Nabavi D.G., Craen R.A., Gelb A.W., and Lee T.Y. Dynamic CT measurement of cerebral blood flow: a validation study. Am J Neuroradiol 20 (1999) 63-73
7. Colbourne F., Corbett D., Zhao Z., Yang J., and Buchan A.M. Prolonged but delayed postischemic hypothermia: a long-term outcome study in the rat middle cerebral artery occlusion model. J Cereb Blood Flow Metab 20 (2000) 1702-1708
8. Dittmar M., Spruss T., Schuierer G., and Horn M. External carotid artery territory ischemia impairs outcome in the endovascular filament model of middle cerebral artery occlusion in rats. STROKE 34 (2003) 2252-2257
9. Farber N.E., Harkin C.P., Niedfeldt J., Hudetz A.G., Kampine J.P., and Schmeling W.T. Region-specific and agent-specific dilation of intracerebral microvessels by volatile anesthetics in rat brain slices. Anesthesiology 87 (1997) 1191-1198
10. Gelb A.W., Bayona N.A., Wilson J.X., and Cechetto D.F. Propofol anesthesia compared to awake reduces infarct size in rats. Anesthesiology 96 (2002) 1183-1190
11. Gelb A.W., Wilson J.X., and Cechetto D.F. Anesthetics and cerebral ischemia-should we continue to dream the impossible dream?. Can J Anaesth 48 (2001) 727-731
12. Globus M.Y., Busto R., Martinez E., Valdes I., Dietrich W.D., and Ginsberg M.D. Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J Neurochem 57 (1991) 470-478
13. Henshall D.C., Butcher S.P., and Sharkey J. A rat model of endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion. Brain Res 843 (1999) 105-111
14. Hansen T.D., Warner D.S., Todd M.M., Vust L.J., and Trawick D.C. Distribution of cerebral blood flow during halothane versus isoflurane anesthesia in rats. Anesthesiology 69 (1988) 332-337
15. Heiss W.D., Kracht L.W., Thiel A., Grond M., and Pawlik G. Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia. Brain 124 (2001) 20-29
16. Hossmann K.A. Viability thresholds and the penumbra of focal ischemia. Ann Neurol 36 (1994) 557-565
17. Hughes P.M., Anthony D.C., Ruddin M., Botham M.S., Rankine E.L., Sablone M., et al. Focal lesions in the rat central nervous system induced by endothelin-1. J Neuropathol Exp Neurol 62 (2003) 1276-1286
18. Kawaguchi M., Drummond J.C., Cole D.J., Kelly P.J., Spurlock M.P., and Patel P.M. Effect of isoflurane on neuronal apoptosis in rats subjected to focal cerebral ischemia. Anesth Anal 98 (2004) 798-805
19. Koizumi J., Yoshida Y., Nakasawa T., and Ooneda G. Experimental studies of ischemic brain edema. I. A new, experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke 8 (1986) 1-8
20. Laing R.J., Jakubowski J., and Laing R.W. Middle cerebral artery occlusion without craniectomy in rats: which method works best?. Stroke 24 (1993) 294-297
21. Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
22. Lumenta D.B., Plesnila N., Klasner B., Baethmann A., Pruneau D., Schmid-Elsaesser R., et al. Neuroprotective effects of a postischemic treatment with a bradykinin B2 receptor antagonist in a rat model of temporary focal ischemia. Brain Res 1069 (2006) 227-234
23. Lyden P.D., Jackson-Friedman C., Shin C., and Hassid S. Synergistic combinatorial stroke therapy: a quantal bioassay of a GABA agonist and a glutamate antagonist. Exp Neurol 163 2 (2000) 477-489
24. Macrae I.M., Robinson M.J., Graham D.I., Reid J.L., and McCulloch J. Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab 13 (1993) 276-284
25. Matlab. The MathWorks I, 1997.
26. Memezawa H., Zhao Q., Smith M.L., and Siesjo B.K. Hyperthermia nullifies the ameliorating effect of dizociline maleate (MK 801) in focal cerebral ischemia. Brain Res 670 (1995) 48-52
27. Middleton D.A., Hockings P.D., Glen S., Reid D.G., Rose S.E., Crozier S., et al. Image directed proton spectroscopy of gerbil brain at 7 Tesla. NMR Biomed 8 (1995) 118-126
28. Moyanova S., Kortenska L., Kirov R., and Iliev I. Quantitative electroencephalographic changes due to middle cerebral artery occlusion by endothelin 1 in conscious rats. Arch Physiol Biochem 106 (1998) 384-391
29. Muller T.B., Haraldseth O., and Unsgard G. Characterisation of the microcirculation during ischemia and reperfusion in the penumbra of a rat model of temporary middle cerebral artery occlusion: a laser Doppler flowmetry study. Int J Microcirc Clin Exp 14 (1994) 289-295
30. Nagel S., Genius J., Heiland S., Hortsmann S., Gardiner H., and Wagner S. Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain Res 1132 (2007) 210-217
31. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 3rd edition (1997), Academic Press Inc., San Diego, California
32. Qiu F., Liu Y., Zhang P.B., Tian Y.F., Qi C.F., Zhao J.J., et al. Effects of ligustrazine on hippocampal dentate gyrus cell proliferation after focal cerebral ischemia in adult rats. Nan Fang Yi Ke Da Xue Xue Bao 26 (2006) 1400-1403
33. Rabb C.H. Nylon monofilament for intraluminal middle cerebral artery occlusion in rats. Stroke 27 (1996) 151 [Letter]
34. Robinson M.J., Macrae I.M., Todd M., Reid J.L., and McCulloch J. Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat. Neurosci Lett 118 (1990) 269-272
35. Sharkey J., Ritchie I.M., and Kelly P.A. Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 13 (1993) 865-871
36. Sharkey J., Butcher S.P., and Kelly J.S. Endothelin-1 induced middle cerebral artery occlusion: pathological consequences and neuroprotective effects of mk801. J Auton Nerv Syst 49 Suppl. (1994) S177-185
37. Sharkey J., and Butcher S.P. Characterisation of an experimental model of stroke produced by intracerebral microinjection of endothelin-1 adjacent to the rat middle cerebral artery. J Neurosci Methods 60 (1995) 125-131
38. Tamura A., Graham D.I., McCulloch J., and Teasdale G.M. Focal cerebral ischaemia in the rat: [2] regional cerebral blood flow determined by [14c]iodoantipyrine autoradiography following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1 (1981) 61-69
39. Tureyen K., Vemuganti R., Sailor K.A., and Dempsey R.J. Infarct volume quantification in mouse focal cerebral ischemia: a comparison of triphenyltetrazolium chloride and cresyl violet staining techniques. J Neurosci Methods 139 (2004) 203-207
40. Villa P., Triulzi S., Cavalieri B., Di Bitondo R., Bertini R., Barbera S., et al. The interleukin (IL-8/CXCL8) receptor inhibitor reparexin improves neurological deficits and reduces long term inflammation in permanent and transient cerebral ischemia in rats. Mol Med 3-4 (2007) 125-133
41. Warner D.S., Zhou J.G., Ramani R., and Todd M.M. Reversible focal ischemia in the rat: effects of halothane, isoflurane, and methohexital anesthesia. J Cereb Blood Flow Metab 11 (1991) 794-802
42. Zhao J.J., Liu Y., Chen X.L., Liu J.X., Tian Y.F., Zhang P.B., et al. Effect of citicoline on spatial learning and memory of rats after focal cerebral ischemia. Nan Fang Yi Ke Da Xue Xue Bao 26 (2006) 174-176