Serovar-specific immune responses to peptides of variable regions of Chlamydia trachomatis major outer membrane protein in serovar D-infected women

Clinical and Experimental Medicine

Volumn 8, Issue 4, 2008, Pages 207-215

  Srivastava, Pragya ^a   Gupta, Rishein ^a   Jha, Hem Chandra ^a   Jha, Rajneesh ^a   Bhengraj, Apurb Rashmi ^a   Salhan, Sudha ^b   Mittal, Aruna ^a  

^a SAFDARJUNG HOSPITAL CAMPUS   (India)

^b SAFDARJUNG HOSPITAL   (India)

Author keywords

Chlamydia trachomatis; Genital tract infection; Immune responses; MOMP; Variable regions

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; MEMBRANE PROTEIN; PEPTIDE; OUTER MEMBRANE PROTEIN;

ADULT; ANTIBODY SPECIFICITY; ARTICLE; CELLULAR IMMUNITY; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

CHLAMYDIA TRACHOMATIS; CHLAMYDIAE;

AMINO ACID SEQUENCE; BACTERIAL OUTER MEMBRANE PROTEINS; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 61549134843     PISSN: 15918890     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10238-008-0004-2     Document Type: Article

References (54)

1. Schachter J, Dawson CR (1978) Human chlamydial infections. PSG, Littleton, MA
2. J Schachter 1999
3. WE Stamm 1999
4. DS LaMontagne DN Fine JM Marrazzo 2003 Chlamydia trachomatis infection in asymptomatic men Am J Prev Med 24 36 42
5. WC Miller CA Ford M Morris 2004 Prevalence of chlamydial and gonococcal infections among young adults in the United States JAMA 291 2229 2236
6. A Mittal S Kapur S Gupta 1993 Chlamydial cervicitis: role of culture, enzyme immunoassay and Giemsa cytology in diagnosis APMIS 101 37 40
7. V Gopalkrishna N Aggarwal VL Malhotra 2000 Chlamydia trachomatis and human papillomavirus infection in Indian women with sexually transmitted diseases and cervical precancerous and cancerous lesions Clin Microbiol Infect 6 88 93
8. V Singh S Rastogi S Garg 2002 Polymerase chain reaction for detection of endocervical C. trachomatis infection in women attending a gynecology outpatient department in India Acta Cytol 46 540 544
9. V Singh S Salhan B Das 2003 Predominance of Chlamydia trachomatis serovars associated with urogenital infections in females in New Delhi, India J Clin Microbiol 41 2700 2702
10. AG Joyee SP Thyagarajan P Rajendran 2004 Evaluation of diagnostic efficacy of PCR methods for Chlamydia trachomatis infection in genital and urine specimens of symptomatic men and women in India Jpn J Infect Dis 56 88 92
11. J Schachter 1978 Chlamydial infections (first of three parts) N Engl J Med 298 428 434
12. World Health Organization (2001) Global prevalence and incidence of selected curable sexually transmitted infections: overview and estimates. WHO, Geneva
13. WL Whittington C Kent P Kissinger 2001 Determinants of persistent and recurrent Chlamydia trachomatis infection in young women: results of a multicenter cohort study Sex Transm Dis 28 117 123
14. S Guaschino G Ricci 2002 How, and how efficiently, can we treat Chlamydia trachomatis infections in women? Best Pract Res Clin Obstet Gynaecol 16 875 888
15. SA Wang JR Papp WE Stamm 2005 Evaluation of antimicrobial resistance and treatment failures for Chlamydia trachomatis: a meeting report J Infect Dis 191 917 923
16. J Debattista P Timms J Allan 2002 Reduced levels of gamma-interferon secretion in response to chlamydial 60 kDa heat shock protein amongst women with pelvic inflammatory disease and a history of repeated Chlamydia trachomatis infections Immunol Lett 81 205 210
17. A Kinnunen HM Surcel M Halttunen 2003 Chlamydia trachomatis heat shock protein-60 induced interferon-gamma and interleukin-10 production in infertile women Clin Exp Immunol 131 299 303
18. CR Cohen KM Koochesfahani AS Meier 2005 Immunoepidemiologic profile of Chlamydia trachomatis infection: importance of heat-shock protein 60 and interferon-γ J Infect Dis 192 591 599
19. S Pal I Theodor EM Peterson 2001 Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challenge Infect Immun 69 6240 6247
20. LM de la Maza EM Peterson 2002 Vaccines for Chlamydia trachomatis infections Curr Opin Investig Drugs 3 980 986
21. JU Igietseme CM Black HD Caldwell 2002 Chlamydia vaccines: strategies and status BioDrugs 16 19 35
22. S Pal EM Peterson LM de la Maza 2005 Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria Infect Immun 73 8153 8160
23. W Baehr YX Zhang T Joseph 1988 Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes Proc Natl Acad Sci USA 85 4000 4004
24. RS Stephens EA Wagar GK Schoolnik 1988 High-resolution mapping of serovar-specific and common antigenic determinants of the major outer membrane protein of Chlamydia trachomatis J Exp Med 167 817 831
25. RC Brunham RW Peeling 1994 Chlamydia trachomatis antigens: role in immunity and pathogenesis Infect Agents Dis 3 218 233
26. HD Caldwell J Kromhout J Schachter 1981 Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis Infect Immun 31 1161 1176
27. BE Batteiger 1996 The major outer membrane protein of a single Chlamydia trachomatis serovar can possess more than one serovar-specific epitope Infect Immun 64 542 547
28. S Bas C Scieux TL Vischer 1999 Different humoral immune response to Chlamydia trachomatis major outer membrane protein variable domains I and IV in Chlamydia-infected patients with or without reactive arthritis Arthritis Rheum 42 942 947
29. JN Arno C Xie RB Jones B Van Der Pol 1998 Identification of T cells that respond to serovar-specific regions of the Chlamydia trachomatis major outer membrane protein in persons with serovar E infection J Infect Dis 178 1713 1718
30. L Oritz M Angevine SK Kim 2000 T-cell epitopes in variable segments of Chlamydia trachomatis major outer membrane protein elicit serovar-specific immune responses in infected humans Infect Immun 68 1719 1723
31. M Klein A Kotz K Bernardo 2003 Detection of Chlamydia pneumoniae-specific antibodies binding to the VD2 and VD3 regions of the major outer membrane protein J Clin Microbiol 41 1957 1962
32. BS Reddy S Rastogi B Das 2004 Cytokine expression pattern in the genital tract of Chlamydia trachomatis positive infertile women-implication for T-cell responses Clin Exp Immunol 137 552 558
33. R Dutta R Jha S Gupta 2007 Seroprevalence of antibodies to conserved region of Chlamydia trachomatis heat shock proteins 60 and 10 in women in India Br J Biomed Sci 64 78 83
34. J Schachter HD Caldwell 1980 Chlamydiae Annu Rev Microbiol 34 285 309
35. Newhall W, Basinski M, Lee CH (1990) Mapping of major outer membrane protein epitopes of Chlamydia trachomatis serovar D. In: Bowie W, Caldwell H, Jones R et al (eds) Chlamydial infections. Proceedings of the Seventh International Symposium on Human Chlamydial Infections. Cambridge University Press, Cambridge, pp 85-88
36. MF Lampe RJ Suchland WE Stamm 1993 Nucleotide sequence of the variable domains within the major outer membrane protein gene from serovariants of Chlamydia trachomatis Infect Immun 61 213 219
37. NR Roan MN Starnbach 2008 Immune-mediated control of Chlamydia infection Cell Microbiol 10 9 19
38. RG Rank BE Batteiger 1989 Protective role of serum antibody in immunity to chlamydial genital infection Infect Immun 57 299 301
39. JU Igietseme KH Ramsey DM Magee 1993 Resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, Th1 lymphocyte clone Reg Immunol 5 317 324
40. H Su HD Caldwell 1995 CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract Infect Immun 63 3302 3308
41. LL Perry K Feilzer HD Caldwell 1997 Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways J Immunol 158 3344 3352
42. RC Brunham J Rey-Ladino 2005 Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine Nat Rev Immunol 5 149 161
43. RP Morrison HD Caldwell 2002 Immunity to murine chlamydial genital infection Infect Immun 70 2741 2751
44. S Wang Y Fan RC Brunham 1999 IFN-gamma knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection Eur J Immunol 29 3782 3792
45. RA Hawkins RG Rank KA Kelly 2002 A Chlamydia trachomatis-specific Th2 clone does not provide protection against a genital infection and displays reduced trafficking to the infected genital mucosa Infect Immun 70 5132 5139
46. RP Morrison 2000 Differential sensitivities of Chlamydia trachomatis strains to inhibitory effects of gamma interferon Infect Immun 68 6038 6040
47. JU Igietseme GA Anabana J Bolier 2000 Suppression of endogenous IL-10 gene expression in dendritic cells enhances antigen presentation for specific Th1 induction: potential for cellular vaccine development J Immunol 164 4212 4219
48. X Yang J Gartner L Zhu 1999 IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection J Immunol 162 1010 1017
49. Y Shemer-Avni D Wallach I Sarov 1988 Inhibition of Chlamydia trachomatis growth by recombinant tumour necrosis factor Infect Immun 56 2503 2506
50. T Darville CW Andrews Jr RG Rank 2000 Does inhibition of tumor necrosis factor alpha affect chlamydial genital tract infection in mice and guinea pigs? Infect Immun 68 5299 5305
51. MJ Holland RL Bailey DJ Conway 1996 T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring Clin Exp Immunol 105 429 435
52. TW Cotter Q Meng ZL Shen 1995 Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection Infect Immun 63 4704 4714
53. FO Eko Q He T Brown 2004 A novel recombinant multisubunit vaccine against Chlamydia J Immunol 173 3375 3382
54. GO Ifere Q He JU Igeitseme 2007 Immunogenicity and protection against genital Chlamydia infection and its complications by a multisubunit candidate vaccine J Microbiol Immunol Infect 40 188 200