Intra-Abdominal Infections

Surgical Clinics of North America

Volumn 89, Issue 2, 2009, Pages 421-437

  Mazuski, John E ^a   Solomkin, Joseph S ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Antimicrobial therapy; Appendicitis; Intra abdominal abscess; Intra abdominal infection; Secondary peritonitis; Source control; Tertiary peritonitis

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAM; BETA LACTAMASE INHIBITOR; CARBAPENEM; CEFAZOLIN; CEFOTAXIME; CEFOTETAN; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CILASTATIN PLUS IMIPENEM; CIPROFLOXACIN; CLINDAMYCIN; DORIPENEM; ERTAPENEM; GENTAMICIN; GLYCYLCYCLINE DERIVATIVE; LEVOFLOXACIN; MEROPENEM; METRONIDAZOLE; MOXIFLOXACIN; NETILMICIN; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULTAMICILLIN; TIGECYCLINE; TIMENTIN; TOBRAMYCIN;

ABDOMINAL DRAINAGE; ABDOMINAL INFECTION; ABSCESS DRAINAGE; ACUTE DISEASE; AEROBIC BACTERIUM; ANAEROBIC BACTERIUM; ANTIMICROBIAL THERAPY; APPENDECTOMY; APPENDICITIS; APPENDIX PERFORATION; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM; BACTEROIDES FRAGILIS; CANDIDA ALBICANS; CATHETER INFECTION; CELL INVASION; CHOLECYSTITIS; CHRONIC DISEASE; CLINICAL FEATURE; CLOSTRIDIA; COMORBIDITY; DISEASE CLASSIFICATION; DIVERTICULITIS; ENTEROBACTER; ENTEROBACTERIACEAE; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FUSOBACTERIUM; GASTROINTESTINAL TRACT; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HISTOPATHOLOGY; HOST RESISTANCE; HUMAN; INDWELLING CATHETER; INTESTINE FLORA; KLEBSIELLA; MORTALITY; OUTCOME ASSESSMENT; PEPTOCOCCUS; PEPTOSTREPTOCOCCUS; PERITONEAL CATHETER; PERITONEAL CAVITY; PERITONEAL DIALYSIS; PERITONITIS; PREVALENCE; PREVENTION AND CONTROL; PRIORITY JOURNAL; PROGNOSIS; PSEUDOMONAS; REVIEW; RISK FACTOR; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; TREATMENT DURATION; TREATMENT OUTCOME; YEAST;

ABDOMINAL ABSCESS; ABDOMINAL CAVITY; ANTI-INFECTIVE AGENTS; APPENDICITIS; COMBINED MODALITY THERAPY; DRUG RESISTANCE; HUMANS; PERITONITIS; SURGICAL WOUND INFECTION;

EID: 61549102820     PISSN: 00396109     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.suc.2008.12.001     Document Type: Review

References (81)

1. Marshall J.C. Intra-abdominal infections. Microbes Infect 6 (2004) 1015-1025
2. Blot S., and De Waele J.J. Critical issues in the clinical management of complicated intra-abdominal infections. Drugs 65 (2005) 1611-1620
3. Solomkin J.S., Hemsell D.L., Sweet R., et al. Evaluation of new anti-infective drugs for the treatment of intra-abdominal infections. Clin Infect Dis 15 (1992) S33-S42
4. Strauss E., and Caly W.R. Spontaneous bacterial peritonitis: a therapeutic update. Expert Rev Anti Infect Ther 4 (2006) 248-260
5. Faber M.D., and Yee J. Diagnosis and management of enteric disease and abdominal catastrophe in peritoneal dialysis patients with peritonitis. Adv Chronic Kidney Dis 13 (2006) 271-279
6. Buijk S.E., and Bruining H.A. Future directions in the management of tertiary peritonitis. Intensive Care Med 28 (2002) 1024-1029
7. Nathens A.B., Rotstein O.D., and Marshall J.C. Tertiary peritonitis: clinical features of a complex nosocomial infection. World J Surg 22 (1998) 158-163
8. Cheadle W.G., and Spain D.A. The continuing challenge of intra-abdominal infections. Am J Surg 186 (2003) 15S-22S
9. Savage D.C. Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 31 (1977) 107-133
10. Mackowiak P.A. The normal microbial flora. N Engl J Med 307 (1982) 83-93
11. Berg R.D. The indigenous gastrointestinal microflora. Trends Microbiol 4 (1996) 430-435
12. Tappenden K.A., and Deutsch A.S. The physiological relevance of the intestinal microbiota - contributions to human health. J Am Coll Nutr 26 (2007) 679S-683S
13. Brook I. Microbiology of polymicrobial abscesses and implications for therapy. J Antimicrob Chemother 50 (2002) 805-810
14. Goldstein E.J.C., and Snydman D.R. Intra-abdominal infections: review of the bacteriology, antimicrobial susceptibility and the role of ertapenem in their therapy. J Antimicrob Chemother 53 (2004) ii29-ii36
15. Roehrborn A., Thomas L., Potreck O., et al. The microbiology of postoperative peritonitis. Clin Infect Dis 33 (2003) 1513-1519
16. Waites K.B., Duffy L.B., and Dowzicky M.J. Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial. Antimicrobial Agents Chemother 50 (2006) 3479-3484
17. Teppler H., McCarroll K., Gesser R.M., et al. Surgical infections with Enterococcus: outcome in patients treated with ertapenem versus piperacillin-tazobactam. Surg Infect (Larchmt) 3 (2002) 337-349
18. Goldstein E.J.C. Intra-abdominal anaerobic infections: bacteriology and therapeutic potential of newer antimicrobial carbapenem, fluoroquinolone, and desfluoroquinolone therapeutic agents. Clin Infect Dis 35 Suppl 1 (2002) S106-S111
19. Reddy B.S., Gatt M., Sowdi R., et al. Gastric colonization predisposes to septic morbidity in surgical patients: a prospective study. Nutrition 24 (2008) 632-637
20. Marshall J.C., Christou N.V., and Meakins J.L. The gastrointestinal tract. The "undrained abscess"of multiple organ failure. Ann Surg 218 (1993) 111-119
21. Sitges-Serra A., Lopez M.J., Girvent M., et al. Postoperative enterococcal infection after treatment of complicated intra-abdominal sepsis. Br J Surg 89 (2002) 361-367
22. Calandra T., Bille J., Schneider R., et al. Clinical significance of Candida isolated from peritoneum in surgical patients. Lancet 2 8677 (1989) 1437-1440
23. Sandven P., and Giercksky K.E. NORGAS Group, Norwegian Yeast Study Group. Yeast colonization in surgical patients with intra-abdominal perforations. Eur J Clin Microbiol Infect Dis 20 (2001) 475-481
24. DeLisle S., and Perl T.M. Vancomycin-resistant enterococci: a road map on how to prevent the emergency and transmission of antimicrobial resistance. Chest 123 (2003) 504S-518S
25. Trick W.E., Fridkin S.K., Edwards J.R., et al. Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999. Clin Infect Dis 35 (2002) 627-630
26. Pfaller M.A., Kiekema D.J., Rinaldi M.G., et al. Results from the ARTEMIS DISK Global Antifungal Surveillance Study: a 6.5-year analysis of susceptibilities of Candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing. J Clin Microbiol 43 (2005) 5848-5859
27. Wacha H., Hau T., Dittmer R., et al. Risk factors associated with intra-abdominal infections: a prospective multicenter study. Langenbecks Arch Surg 384 (1999) 24-32
28. Mulier S., Penninckx F., Verwaest C., et al. Factors affecting mortality in generalized postoperative peritonitis: multivariate analysis in 96 patients. World J Surg 27 (2003) 379-384
29. Betsch A., Wiskirchen J., Trübenbach J., et al. CT-guided percutaneous drainage of intra-abdominal abscesses: APACHE III score stratification of 1-year results. Eur Radiol 12 (2002) 2883-2889
30. Theisen J., Bartels H., Weiss W., et al. Current concepts of percutaneous abscess drainage in postoperative retention. J Gastrointest Surg 9 (2005) 280-283
31. Watters J.M. Acute appendicitis. In: Schein M., and Marshall J.C. (Eds). Source control (2003), Springer-Verlag, Berlin 124-130
32. Mason R.J. Surgery for appendicitis: is it necessary?. Surg Infect (Larchmt) 9 (2008) 481-488
33. Adams M.L. The medical management of acute appendicitis in a nonsurgical environment: a retrospective case review. Mil Med 155 (1990) 345-347
34. Eriksson S., and Granström L. Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis. Br J Surg 82 (1995) 166-169
35. Styrud J., Eriksson S., Nilsson I., et al. Appendectomy versus antibiotic treatment in acute appendicitis. A prospective multicenter randomized controlled trial. World J Surg 30 (2006) 1033-1037
36. Blomqvist P.G., Andersson R.E., Granath F., et al. Mortality after appendectomy in Sweden, 1987-1996. Ann Surg 233 (2001) 455-460
37. Andersson R.E. Small bowel obstruction after appendicectomy. Br J Surg 88 (2001) 1387-1391
38. Andersson R.E., and Petzold M.G. Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg 246 (2007) 741-748
39. Van Ruler O., Mahler C.W., Boer K.R., et al. Comparison of on-demand vs planned relaparotomy strategy in patients with severe peritonitis. A randomized trial. JAMA 298 (2007) 865-873
40. Mazuski J.E., Sawyer R.G., Nathens A.B., et al. The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: an executive summary. Surg Infect (Larchmt) 3 (2002) 161-173
41. Solomkin J.S., Mazuski J.E., Baron E.J., et al. Guidelines for the selection of anti-infective agents for intra-abdominal infections. Clin Infect Dis 37 (2003) 997-1005
42. Wong P.F., Gilliam A.D., Kumar S., et al. Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults. Cochrane Database Syst Rev 2 (2005) CD004539
43. Sturkenboom M.C.J.M., Goettsch W.G., Picelli G., et al. Inappropriate initial treatment of secondary intra-abdominal infections leads to increased risk of clinical failure and costs. Br J Clin Pharmacol 60 (2005) 438-443
44. Edelsberg J., Berger A., and Schell S. Economic consequences of failure of initial antibiotic therapy in hospitalized adults with complicated intra-abdominal infections. Surg Infect (Larchmt) 9 (2008) 335-347
45. Merlino J.I., Malangoni M.A., Smith C.M., et al. Prospective randomized trials affect the outcomes of intraabdominal infection. Ann Surg 233 (2001) 859-866
46. Mazuski J.E., Sawyer R.G., Nathens A.B., et al. The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: evidence for the recommendations. Surg Infect (Larchmt) 3 (2002) 175-233
47. Bailey J.A., Virgo K.S., DiPiro J.T., et al. Aminoglycosides for intra-abdominal infection: equal to the challenge?. Surg Infect (Larchmt) 3 (2002) 315-335
48. Chow J.W., Satishchandran V., Snyder T.A., et al. In vitro susceptibilities of aerobic and facultative gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: the 2002 Study for Monitoring Antimicrobial Resistance Trends (SMART). Surg Infect (Larchmt) 6 (2005) 439-448
49. Dupont H. The empiric treatment of nosocomial intra-abdominal infections. Int J Infect Dis 11 (2007) S1-S6
50. Snydman D.R., Jacobus N.V., McDermott L.A., et al. Multicenter study of in vitro susceptibility of the Bacteroides fragilis group, 1995 to 1996, with comparison of resistance trends from 1990 to 1996. Antimicrobial Agents Chemother 43 (1999) 2417-2422
51. Aldridge K.E., Ashcraft D., Cambre K., et al. Multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of Bacteroides fragilis group, Prevotella, Fusobacterium, Porphyromonas, and Peptostreptococcus species. Antimicrobial Agents Chemother 45 (2001) 1238-1243
52. Krobot K., Yin D., Zhang Q., et al. Effect of inappropriate initial empiric antibiotic therapy on outcome of patients with community-acquired intra-abdominal infections requiring surgery. Eur J Clin Microbiol Infect Dis 23 (2004) 682-687
53. Montravers P., Gauzit R., Muller C., et al. Emergence of antibiotic-resistant bacteria in cases of peritonitis after intra-abdominal surgery affects the efficacy of empirical antimicrobial therapy. Clin Infect Dis 23 (1996) 486-494
54. Chastre J., and Fagon J.Y. Ventilator-associated pneumonia. Am J Respir Crit Care Med 165 (2002) 867-903
55. Mazuski J.E. Clinical challenges and unmet needs in the management of complicated intra-abdominal infections. Surg Infect (Larchmt) 6 (2005) S49-S69
56. Anaya D.A., and Nathens A.B. Risk factors for severe sepsis in secondary peritonitis. Surg Infect (Larchmt) 4 (2003) 355-362
57. Hopkins J.A., Lee J.C.H., and Wilson S.E. Susceptibility of intra-abdominal isolates at operation: a predictor of postoperative infection. Am Surg 59 (1993) 791-796
58. Christou N.V., Turgeon P., Wassef R., et al. Management of intra-abdominal infections. The case for intraoperative cultures and comprehensive broad-spectrum antibiotic coverage. Arch Surg 131 (1996) 1193-1201
59. Barie P.S., Vogel S.B., Dellinger E.P., et al. A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Arch Surg 132 (1997) 1294-1302
60. Solomkin J.S. Antibiotic resistance in postoperative infections. Crit Care Med 29 (2001) N97-N99
61. Burnett R.J., Haverstock D.C., Dellinger E.P., et al. Definition of the role of enterococcus in intra-abdominal infection: analysis of a prospective randomized trial. Surgery 118 (1995) 716-723
62. Sotto A., Lefrant J.Y., Fabbro-Peray P., et al. Evaluation of antimicrobial therapy management of 120 consecutive patients with secondary peritonitis. J Antimicrob Chemother 50 (2002) 569-576
63. Harbarth S., and Uckay I. Are there patients with peritonitis who require empiric therapy for Enterococcus?. Eur J Clin Microbiol Infect Dis 23 (2004) 73-77
64. Solomkin J.S., Flohr A.B., Quie P.G., et al. The role of Candida in intraperitoneal infections. Surgery 88 (1980) 524-530
65. Eggiman P., Francioli P., Bille J., et al. Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients. Crit Care Med 27 (1999) 1066-1072
66. Mazuski J.E. Antimicrobial treatment for intra-abdominal infections. Expert Opin Pharmacother 8 (2007) 2933-2945
67. Paterson D.L. "Collateral damage" from cephalosporin or quinolone antibiotic therapy. Clin Infect Dis 38 Suppl 4 (2004) S341-S345
68. Raymond D.P., Kuehnert M.J., and Sawyer R.G. Preventing antimicrobial-resistant bacterial infections in surgical patients. Surg Infect (Larchmt) 3 (2002) 375-385
69. Davey P., Brown E., and Fenelon L. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev 4 (2005) CD003543
70. Dellit T.H., Owens R.C., McGowan Jr. J.E., et al. Guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 44 (2007) 159-177
71. Gleisner A.L., Argenta R., Pimentel M., et al. Infective complications according to duration of antibiotic treatment in acute abdomen. Int J Infect Dis 8 (2004) 155-162
72. Smith J.A., Bell G.A., Murphy J., et al. Evaluation of the use of a protocol in the antimicrobial treatment of intra-abdominal sepsis. J Hosp Infect 6 (1985) 60-64
73. Taylor E., Dev V., Shah D., et al. Complicated appendicitis: is there a minimum intravenous antibiotic requirement? A prospective randomized trial. Am Surg 66 (2000) 887-890
74. Schein M., Assalia A., and Bachus H. Minimal antibiotic therapy after emergency abdominal surgery: a prospective study. Br J Surg 81 (1994) 989-991
75. Andåker L., Höjer H., Kihlström E., et al. Stratified duration of prophylactic antimicrobial treatment in emergency abdominal surgery. Metronidazole-fosfomycin vs. metronidazole-gentamicin in 381 patients. Acta Chir Scand 153 (1987) 185-192
76. Basoli A., Chirletti P., Cirino E., et al. A prospective, double-blind, multicenter, randomized trial comparing ertapenem 3 vs. ≥5 days in community-acquired intraabdominal infection. J Gastrointest Surg 12 (2008) 592-600
77. Malangoni M.A., Song J., Herrington J., et al. Randomized controlled trial of moxifloxacin compared with piperacillin-tazobactam and amoxicillin-clavulanate for the treatment of complicated intra-abdominal infections. Ann Surg 244 (2006) 204-211
78. Babinchak T., Ellis-Grosse E., Dartois N., et al. The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical data. Clin Infect Dis 41 Suppl 5 (2005) S354-S367
79. Lucasti C., Abel Jasovich A., Umeh O., et al. Efficacy and tolerability of IV doripenem versus meropenem in adults with complicated intra-abdominal infection: a phase III, prospective, multicenter, randomized, double-blind, noninferiority study. Clin Ther 30 (2008) 868-883
80. Wilson S.E., and Faulkner K. Impact of anatomical site on bacteriological and clinical outcome in the management of intra-abdominal infections. Am Surg 64 (1998) 402-407
81. Mosdell D.M., Morris D.M., Voltura A., et al. Antibiotic treatment for surgical peritonitis. Ann Surg 214 (1991) 543-549