메뉴 건너뛰기




Volumn 9, Issue 1, 2009, Pages 1-5

Promises and challenges of human papillomavirus vaccines for cervical cancer

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN L1; CISPLATIN; PROTEIN E7; QUIL A; WART VIRUS VACCINE; HUMAN PAPILLOMAVIRUS VACCINE L1, TYPE 6,11,16,18; UNCLASSIFIED DRUG;

EID: 61449505262     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.9.1.1     Document Type: Editorial
Times cited : (7)

References (54)
  • 1
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
    • Munger K, Phelps WC, Bubb V, Howley PM, Schlegel R. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol. 63, 4417-4421 (1989).
    • (1989) J. Virol , vol.63 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 2
    • 0024535228 scopus 로고
    • The human papillomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product
    • Dyson N, Howley PM, Munger K, Harlow E. The human papillomavirus-16 E7 oncoprotein is able to bind the retinoblastoma gene product. Science 243, 934-937 (1989).
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 3
    • 0025953696 scopus 로고
    • The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • Scheffner M, Munger K, Bryne JC, Howley PM. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl Acad. Sci. USA 88, 5523-5527 (1991).
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Munger, K.2    Bryne, J.C.3    Howley, P.M.4
  • 4
    • 0025271203 scopus 로고
    • Association of HPV type 16 and 18 E6 protein with p53
    • Werness BA, Levine AJ, Howley PM. Association of HPV type 16 and 18 E6 protein with p53. Science 248, 76-79 (1990).
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 5
    • 0033561333 scopus 로고    scopus 로고
    • Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer
    • Rose P, Bundy BN, Watkins EB et al. Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N. Engl. J. Med. 340, 1144-1153 (1999).
    • (1999) N. Engl. J. Med , vol.340 , pp. 1144-1153
    • Rose, P.1    Bundy, B.N.2    Watkins, E.B.3
  • 6
    • 0035828388 scopus 로고    scopus 로고
    • Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: A systematic review and meta-analysis
    • Green JA, Kirwan JM, Tierney JF et al. Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis. Lancet 358, 781-786 (2001).
    • (2001) Lancet , vol.358 , pp. 781-786
    • Green, J.A.1    Kirwan, J.M.2    Tierney, J.F.3
  • 7
    • 0030934907 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte responses to E6 and E7 proteins of human papillomavirus type 16: Relationship to cervical intraepithelial neoplasia
    • Nakagawa M, Stites DP, Farhat S et al. Cytotoxic T lymphocyte responses to E6 and E7 proteins of human papillomavirus type 16: relationship to cervical intraepithelial neoplasia. J. Infect. Dis. 175, 927-931 (1997).
    • (1997) J. Infect. Dis , vol.175 , pp. 927-931
    • Nakagawa, M.1    Stites, D.P.2    Farhat, S.3
  • 8
    • 0033844534 scopus 로고    scopus 로고
    • Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens
    • Nakagawa M, Stites DP, Patel S et al. Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens. J. Infect. Dis. 182, 595-598 (2000).
    • (2000) J. Infect. Dis , vol.182 , pp. 595-598
    • Nakagawa, M.1    Stites, D.P.2    Patel, S.3
  • 9
    • 28844450322 scopus 로고    scopus 로고
    • Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study
    • Sarkar AK, Tortolero-Luna G, Follen M, Sastry KJ. Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study. Gynecol. Oncol. 99, S251-S261 (2005).
    • (2005) Gynecol. Oncol , vol.99
    • Sarkar, A.K.1    Tortolero-Luna, G.2    Follen, M.3    Sastry, K.J.4
  • 10
    • 33846444354 scopus 로고    scopus 로고
    • High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer
    • Piersma SJ, Jordanova ES, van Poelgeest MI et al. High number of intraepithelial CD8+ tumor-infiltrating lymphocytes is associated with the absence of lymph node metastases in patients with large early-stage cervical cancer. Cancer Res. 67, 354-361 (2007).
    • (2007) Cancer Res , vol.67 , pp. 354-361
    • Piersma, S.J.1    Jordanova, E.S.2    van Poelgeest, M.I.3
  • 11
    • 0036204348 scopus 로고    scopus 로고
    • Cancer immunotherapy using Sindbis virus replicon particles encoding a VP22-antigen fusion
    • Cheng WF, Hung CF, Hsu KF et al. Cancer immunotherapy using Sindbis virus replicon particles encoding a VP22-antigen fusion. Hum. Gene Ther. 13, 553-568 (2002).
    • (2002) Hum. Gene Ther , vol.13 , pp. 553-568
    • Cheng, W.F.1    Hung, C.F.2    Hsu, K.F.3
  • 13
    • 0142105977 scopus 로고    scopus 로고
    • A therapy modality using recombinant IL-12 adenovirus plus E7 protein in a human papillomavirus 16 E6/ E7-associated cervical cancer animal model
    • Ahn WS, Bae SM, Kim TY et al. A therapy modality using recombinant IL-12 adenovirus plus E7 protein in a human papillomavirus 16 E6/ E7-associated cervical cancer animal model. Hum. Gene Ther. 14, 1389-1399 (2003).
    • (2003) Hum. Gene Ther , vol.14 , pp. 1389-1399
    • Ahn, W.S.1    Bae, S.M.2    Kim, T.Y.3
  • 14
    • 0344736643 scopus 로고    scopus 로고
    • An adenoviral vector cancer vaccine that delivers a tumor-associated antigen/CD40-ligand fusion protein to dendritic cells
    • Zhang L, Tang Y, Akbulut H, Zelterman D, Linton PJ, Deisseroth AB. An adenoviral vector cancer vaccine that delivers a tumor-associated antigen/CD40-ligand fusion protein to dendritic cells. Proc. Natl Acad. Sci. USA 100, 15101-15106 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 15101-15106
    • Zhang, L.1    Tang, Y.2    Akbulut, H.3    Zelterman, D.4    Linton, P.J.5    Deisseroth, A.B.6
  • 15
    • 1642453782 scopus 로고    scopus 로고
    • Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6
    • Kim TW, Hung CF, Boyd DA et al. Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6. Cancer Res. 64, 400-405 (2004).
    • (2004) Cancer Res , vol.64 , pp. 400-405
    • Kim, T.W.1    Hung, C.F.2    Boyd, D.A.3
  • 16
    • 84984550385 scopus 로고    scopus 로고
    • Vaccination with a DNA vaccine encoding herpes simplex virus type 1 VP22 linked to antigen generates long-term antigen-specific CD8-positive memory T cells and protective immunity
    • Kim TW, Hung CF, Kim JW et al. Vaccination with a DNA vaccine encoding herpes simplex virus type 1 VP22 linked to antigen generates long-term antigen-specific CD8-positive memory T cells and protective immunity. Hum. Gene Ther. 15, 167-177 (2004).
    • (2004) Hum. Gene Ther , vol.15 , pp. 167-177
    • Kim, T.W.1    Hung, C.F.2    Kim, J.W.3
  • 17
    • 25444459127 scopus 로고    scopus 로고
    • Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7-expressing animal tumour model
    • Kim MS, Sin JI. Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7-expressing animal tumour model. Immunol. 116, 255-266 (2005).
    • (2005) Immunol , vol.116 , pp. 255-266
    • Kim, M.S.1    Sin, J.I.2
  • 18
    • 33744804579 scopus 로고    scopus 로고
    • Anti-tumor therapeutic effects of E7 subunit and DNA vaccines in an animal cervical cancer model: Anti-tumor efficacy of E7 therapeutic vaccines is dependent on tumor sizes, vaccine doses, and vaccine delivery routes
    • Sin JI, Hong SH, Park YJ, Park JB, Choi YS, Kim, MS. Anti-tumor therapeutic effects of E7 subunit and DNA vaccines in an animal cervical cancer model: anti-tumor efficacy of E7 therapeutic vaccines is dependent on tumor sizes, vaccine doses, and vaccine delivery routes. DNA Cell Biol. 25, 277-286 (2006).
    • (2006) DNA Cell Biol , vol.25 , pp. 277-286
    • Sin, J.I.1    Hong, S.H.2    Park, Y.J.3    Park, J.B.4    Choi, Y.S.5    Kim, M.S.6
  • 19
    • 33846302030 scopus 로고    scopus 로고
    • Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: Causal involvement of increased sensitivity of cisplatin-treated tumors to CTL-mediated killing in therapeutic synergy
    • Bae SH, Park YJ, Choi YS, Park JB, Kim MS, Sin JI. Therapeutic synergy of human papillomavirus E7 subunit vaccines plus cisplatin in an animal tumor model: causal involvement of increased sensitivity of cisplatin-treated tumors to CTL-mediated killing in therapeutic synergy. Clin. Cancer Res. 13, 341-349 (2007).
    • (2007) Clin. Cancer Res , vol.13 , pp. 341-349
    • Bae, S.H.1    Park, Y.J.2    Choi, Y.S.3    Park, J.B.4    Kim, M.S.5    Sin, J.I.6
  • 20
    • 0032995535 scopus 로고    scopus 로고
    • Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16
    • Fernando GJP, Murray B, Zhou J, Frazer IH. Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16. Clin. Exp. Immunol. 115, 397-403 (1999).
    • (1999) Clin. Exp. Immunol , vol.115 , pp. 397-403
    • Fernando, G.J.P.1    Murray, B.2    Zhou, J.3    Frazer, I.H.4
  • 21
    • 26244465082 scopus 로고    scopus 로고
    • Liposome-polycation-DNA LPD) particle as a carrier and adjuvant for protein-based vaccines: Therapeutic effect against cervical cancer
    • Cui Z, Huang L. Liposome-polycation-DNA LPD) particle as a carrier and adjuvant for protein-based vaccines: therapeutic effect against cervical cancer. Cancer Immunol. Immunother. 54, 1180-1190 (2005).
    • (2005) Cancer Immunol. Immunother , vol.54 , pp. 1180-1190
    • Cui, Z.1    Huang, L.2
  • 22
    • 0036644556 scopus 로고    scopus 로고
    • Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
    • Zwaveling S, Ferreira Mota SC, Nouta J et al. Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J. Immunol. 169, 350-358 2002).
    • (2002) J. Immunol , vol.169 , pp. 350-358
    • Zwaveling, S.1    Ferreira Mota, S.C.2    Nouta, J.3
  • 23
    • 26244465082 scopus 로고    scopus 로고
    • Synthetic double-stranded RNA poly(I:C) as a potent peptide vaccine adjuvant: Therapeutic activity against human cervical cancer in a rodent model
    • Cui Z, Qiu F, Synthetic double-stranded RNA poly(I:C) as a potent peptide vaccine adjuvant: therapeutic activity against human cervical cancer in a rodent model. Cancer Immunol. Immunother. 54, 1180-1190 (2005).
    • (2005) Cancer Immunol. Immunother , vol.54 , pp. 1180-1190
    • Cui, Z.1    Qiu, F.2
  • 24
    • 0031204408 scopus 로고    scopus 로고
    • The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection
    • Livingston BD, Crimi C, Grey H et al. The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection. J. Immunol. 159, 1383-1392 (1997).
    • (1997) J. Immunol , vol.159 , pp. 1383-1392
    • Livingston, B.D.1    Crimi, C.2    Grey, H.3
  • 25
    • 0342647378 scopus 로고    scopus 로고
    • Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine
    • Gahery-Segard H, Pialoux G, Charmeteau B et al. Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine. J. Virol. 74, 1694-1703 (2000).
    • (2000) J. Virol , vol.74 , pp. 1694-1703
    • Gahery-Segard, H.1    Pialoux, G.2    Charmeteau, B.3
  • 26
    • 0032899613 scopus 로고    scopus 로고
    • + T-cell help is required for induction of antipeptide multispecific cytotoxic T lymphocytes by a lipopeptidic vaccine in rhesus macaques
    • + T-cell help is required for induction of antipeptide multispecific cytotoxic T lymphocytes by a lipopeptidic vaccine in rhesus macaques. J. Virol. 73, 4447-4451 (1999).
    • (1999) J. Virol , vol.73 , pp. 4447-4451
    • Mortara, L.1    Gras-Masse, H.2    Rommens, C.3    Venet, A.4    Guillet, J.G.5    Bourgault-Villada, I.6
  • 27
    • 12544257675 scopus 로고    scopus 로고
    • Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein
    • Preville X, Ladant D, Timmerman B, Leclerc C. Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein. Cancer Res. 65, 641-649 (2005).
    • (2005) Cancer Res , vol.65 , pp. 641-649
    • Preville, X.1    Ladant, D.2    Timmerman, B.3    Leclerc, C.4
  • 28
    • 0033589811 scopus 로고    scopus 로고
    • Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the anti-tumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors
    • Ji H, Wang TL, Chen CH et al. Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the anti-tumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Hum. Gene Ther. 10, 2727-2740 1999).
    • (1999) Hum. Gene Ther , vol.10 , pp. 2727-2740
    • Ji, H.1    Wang, T.L.2    Chen, C.H.3
  • 29
    • 0035328523 scopus 로고    scopus 로고
    • Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen
    • Hung CF, Cheng WF, Hsu KF et al. Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen. Cancer Res. 61, 3698-3703 (2001).
    • (2001) Cancer Res , vol.61 , pp. 3698-3703
    • Hung, C.F.1    Cheng, W.F.2    Hsu, K.F.3
  • 30
    • 0034788572 scopus 로고    scopus 로고
    • Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen
    • Cheng WF, Hung CF, Chai CY et al. Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. J. Clin. Invest. 108, 669-678 2001).
    • (2001) J. Clin. Invest , vol.108 , pp. 669-678
    • Cheng, W.F.1    Hung, C.F.2    Chai, C.Y.3
  • 31
    • 0036184794 scopus 로고    scopus 로고
    • Improving DNA vaccine potency by linking Marek's disease virus type 1 VP22 to an antigen
    • Hung CF, He L, Juang J, Lin TJ, Ling M, Wu TC. Improving DNA vaccine potency by linking Marek's disease virus type 1 VP22 to an antigen. J. Virol. 76, 2676-2682 (2002).
    • (2002) J. Virol , vol.76 , pp. 2676-2682
    • Hung, C.F.1    He, L.2    Juang, J.3    Lin, T.J.4    Ling, M.5    Wu, T.C.6
  • 32
    • 0038520125 scopus 로고    scopus 로고
    • Enhancing major histocompatibility complex class I antigen presentation by targeting antigen to centrosomes
    • Hung CF, Cheng WF, He L et al. Enhancing major histocompatibility complex class I antigen presentation by targeting antigen to centrosomes. Cancer Res. 63, 2393-2398 (2003).
    • (2003) Cancer Res , vol.63 , pp. 2393-2398
    • Hung, C.F.1    Cheng, W.F.2    He, L.3
  • 33
    • 0042964824 scopus 로고    scopus 로고
    • Enhancing DNA vaccine potency by coadministration of DNA encoding anti-apoptotic proteins
    • Kim TW, Hung CF, Ling M et al. Enhancing DNA vaccine potency by coadministration of DNA encoding anti-apoptotic proteins. J. Clin. Invest. 112, 109-117 (2003).
    • (2003) J. Clin. Invest , vol.112 , pp. 109-117
    • Kim, T.W.1    Hung, C.F.2    Ling, M.3
  • 34
    • 7244253006 scopus 로고    scopus 로고
    • Multistep process through which adenoviral vector vaccine overcomes anergy to tumorassociated antigens
    • Tang Y, Zhang L, Yuan J et al. Multistep process through which adenoviral vector vaccine overcomes anergy to tumorassociated antigens. Blood 104, 2704-2713 (2004).
    • (2004) Blood , vol.104 , pp. 2704-2713
    • Tang, Y.1    Zhang, L.2    Yuan, J.3
  • 35
    • 2342548726 scopus 로고    scopus 로고
    • CpG-ODN-stimulated dendritic cells act as a potent adjuvant for E7 protein delivery to induce antigen-specific anti-tumor immunity in a HPV 16 (E6/E7)-associated tumor animal model
    • Kim TG, Kim CH, Won EH et al. CpG-ODN-stimulated dendritic cells act as a potent adjuvant for E7 protein delivery to induce antigen-specific anti-tumor immunity in a HPV 16 (E6/E7)-associated tumor animal model. Immunology 112, 117-125 (2004).
    • (2004) Immunology , vol.112 , pp. 117-125
    • Kim, T.G.1    Kim, C.H.2    Won, E.H.3
  • 36
    • 28244455880 scopus 로고    scopus 로고
    • A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors
    • Bermudez-Humaran LG, Cortes-Perez NG, Lefevre F et al. A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors. J. Immunol. 175, 7297-7302 (2005).
    • (2005) J. Immunol , vol.175 , pp. 7297-7302
    • Bermudez-Humaran, L.G.1    Cortes-Perez, N.G.2    Lefevre, F.3
  • 37
    • 7444252881 scopus 로고    scopus 로고
    • Failed adoptive immunotherapy with tumor-specific T cells: Reversal with low-dose interleukin 15 but not low-dose interleukin 2
    • Roychowdhury S, May KF Jr, Tzou KS et al. Failed adoptive immunotherapy with tumor-specific T cells: reversal with low-dose interleukin 15 but not low-dose interleukin 2. Cancer Res. 64, 8062-8067 (2004).
    • (2004) Cancer Res , vol.64 , pp. 8062-8067
    • Roychowdhury, S.1    May Jr, K.F.2    Tzou, K.S.3
  • 39
    • 31144434868 scopus 로고    scopus 로고
    • + Regulatory T cell depletion augments immunotherapy of micrometastases by an IL-21-secreting cellular vaccine
    • + Regulatory T cell depletion augments immunotherapy of micrometastases by an IL-21-secreting cellular vaccine. J. Immunol. 176, 1750-1758 (2006).
    • (2006) J. Immunol , vol.176 , pp. 1750-1758
    • Comes, A.1    Rosso, O.2    Orengo, A.M.3
  • 40
    • 33748957938 scopus 로고    scopus 로고
    • + regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice
    • + regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice. Ann. Surg. Oncol. 13, 1252-1258 (2006).
    • (2006) Ann. Surg. Oncol , vol.13 , pp. 1252-1258
    • Viehl, C.T.1    Moore, T.T.2    Liyanage, U.K.3
  • 42
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colonystimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colonystimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J. Exp. Med. 190, 355-366 (1999).
    • (1999) J. Exp. Med , vol.190 , pp. 355-366
    • van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 43
    • 33745851479 scopus 로고    scopus 로고
    • CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
    • Quezada SA, Peggs KS, Curran MA, Allison JP. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J. Clin. Invest. 116, 1935-1945 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 1935-1945
    • Quezada, S.A.1    Peggs, K.S.2    Curran, M.A.3    Allison, J.P.4
  • 44
    • 0033813525 scopus 로고    scopus 로고
    • A Phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive
    • Muderspach L, Wilczynski S, Roman L et al. A Phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. Clin. Cancer Res. 6, 3406-3416 (2000).
    • (2000) Clin. Cancer Res , vol.6 , pp. 3406-3416
    • Muderspach, L.1    Wilczynski, S.2    Roman, L.3
  • 45
    • 33646817087 scopus 로고    scopus 로고
    • Regression of papilloma high-grade lesions (CIN 2 and CIN 3) is stimulated by therapeutic vaccination with MVA E2 recombinant vaccine
    • Garcia-Hernandez E, Gonzalez-Sanchez JL, Andrade-Manzano A et al. Regression of papilloma high-grade lesions (CIN 2 and CIN 3) is stimulated by therapeutic vaccination with MVA E2 recombinant vaccine. Cancer Gene Ther. 13, 592-597 (2006).
    • (2006) Cancer Gene Ther , vol.13 , pp. 592-597
    • Garcia-Hernandez, E.1    Gonzalez-Sanchez, J.L.2    Andrade-Manzano, A.3
  • 46
    • 34548127036 scopus 로고    scopus 로고
    • A Phase II study of hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia
    • Roman L, Wilczynski S, Muderspach LI et al. A Phase II study of hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia. Gynecol. Oncol. 106, 558-566 (2007).
    • (2007) Gynecol. Oncol , vol.106 , pp. 558-566
    • Roman, L.1    Wilczynski, S.2    Muderspach, L.I.3
  • 47
    • 36248945563 scopus 로고    scopus 로고
    • Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3)
    • Kaufmann, A., Nieland, JD, Jochmus I et al. Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3). Int. J. Cancer 121, 2794-2800 (2007).
    • (2007) Int. J. Cancer , vol.121 , pp. 2794-2800
    • Kaufmann, A.1    Nieland, J.D.2    Jochmus, I.3
  • 48
    • 0033153564 scopus 로고    scopus 로고
    • Vaccination with HPV 16 peptides of patients with advanced cervical carcinoma: Clinical evaluation of a Phase I-II trial
    • van Driel WJ, Ressing ME, Kenter GG et al. Vaccination with HPV 16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a Phase I-II trial. Eur. J. Cancer 35, 946-952 (1999).
    • (1999) Eur. J. Cancer , vol.35 , pp. 946-952
    • van Driel, W.J.1    Ressing, M.E.2    Kenter, G.G.3
  • 49
    • 0141528515 scopus 로고    scopus 로고
    • Dendritic cell-based tumor vaccine for cervical cancer II: Results of a clinical pilot study in 15 individual patients
    • Ferrara A, Nonn M, Sehr P et al. Dendritic cell-based tumor vaccine for cervical cancer II: results of a clinical pilot study in 15 individual patients. J. Cancer Res. Clin. Oncol. 129, 521-530 (2003).
    • (2003) J. Cancer Res. Clin. Oncol , vol.129 , pp. 521-530
    • Ferrara, A.1    Nonn, M.2    Sehr, P.3
  • 50
    • 32644462764 scopus 로고    scopus 로고
    • HPV 16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities
    • Santin AD, Bellone S, Palmieri M et al. HPV 16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities. Gynecol. Oncol. 100, 469-478 (2006).
    • (2006) Gynecol. Oncol , vol.100 , pp. 469-478
    • Santin, A.D.1    Bellone, S.2    Palmieri, M.3
  • 51
    • 15844365301 scopus 로고    scopus 로고
    • A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer
    • Borysiewicz LK, Fiander A, Nimako M et al. A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer. Lancet 347, 1523-1527 (1996).
    • (1996) Lancet , vol.347 , pp. 1523-1527
    • Borysiewicz, L.K.1    Fiander, A.2    Nimako, M.3
  • 52
    • 0036894973 scopus 로고    scopus 로고
    • Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer
    • Kaufmann AM, Stern PL, Rankin EM et al. Safety and immunogenicity of TA-HPV, a recombinant vaccinia virus expressing modified human papillomavirus (HPV)-16 and HPV-18 E6 and E7 genes, in women with progressive cervical cancer. Clin. Cancer Res. 8, 3676-3685 (2002).
    • (2002) Clin. Cancer Res , vol.8 , pp. 3676-3685
    • Kaufmann, A.M.1    Stern, P.L.2    Rankin, E.M.3
  • 53
    • 34547133955 scopus 로고    scopus 로고
    • Increased sensitivity of radiated murine cervical cancer tumors to E7 subunit vaccine-driven CTL-mediated killing induces synergistic anti-tumor activity
    • Ye GW, Park JB, Park YJ, Choi YS, Sin JI. Increased sensitivity of radiated murine cervical cancer tumors to E7 subunit vaccine-driven CTL-mediated killing induces synergistic anti-tumor activity. Mol. Ther. 15, 1564-1570 (2007).
    • (2007) Mol. Ther , vol.15 , pp. 1564-1570
    • Ye, G.W.1    Park, J.B.2    Park, Y.J.3    Choi, Y.S.4    Sin, J.I.5
  • 54
    • 48149087775 scopus 로고    scopus 로고
    • + T-cellmediated anti-tumor immunity induced by DNA vaccination
    • + T-cellmediated anti-tumor immunity induced by DNA vaccination. J. Mol. Med. 86, 899-908 (2008).
    • (2008) J. Mol. Med , vol.86 , pp. 899-908
    • Tseng, C.1    Monie, A.2    Wu, C.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.