The polymorphisms of TS and MTHFR predict survival of gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy in Chinese population

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 5, 2009, Pages 911-918

  Huang, Zhao Hui ^a   Hua, Dong ^a   Li, Li Hua ^a  

^a Soochow University   (China)

Author keywords

5 Fluorouracil; Adjuvant chemotherapy; Gastric cancer; Methylenetetrahydrofolate reductase; Polymorphism; Thymidylate synthase

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTINEOPLASTIC AGENT; FLUOROURACIL; FOLINIC ACID; HYDROXYCAMPTHECIN; OXALIPLATIN; TAXANE DERIVATIVE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; ARTICLE; BLOOD SAMPLING; CANCER ADJUVANT THERAPY; CANCER RELAPSE; CANCER SURVIVAL; CHINESE; CONTROLLED STUDY; DNA POLYMORPHISM; ENHANCER REGION; FEMALE; GENE DELETION; GENE INSERTION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; STOMACH CANCER; TANDEM REPEAT; TREATMENT OUTCOME;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CHINA; COHORT STUDIES; FEMALE; FLUOROURACIL; GENOTYPE; HUMANS; INTESTINAL NEOPLASMS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; SEQUENCE DELETION; STOMACH NEOPLASMS; SURVIVAL RATE; TANDEM REPEAT SEQUENCES; TAXOIDS; THYMIDYLATE SYNTHASE; TREATMENT OUTCOME;

EID: 61449259904     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0815-6     Document Type: Article

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