All three subunits of soybean β-conglycinin are potential food allergens

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 3, 2009, Pages 938-943

  Krishnan, Hari B ^a,b   Kim, Won Seok ^b   Jang, Sungchan ^b   Kerley, Monty S ^b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

conglycinin; Allergen; Glycoprotein; IgE reactivity; Soybeans

Indexed keywords

ESCHERICHIA COLI; GLYCINE MAX;

ALLERGEN; BETA CONGLYCININ PROTEIN, GLYCINE MAX; BETA-CONGLYCININ PROTEIN, GLYCINE MAX; GLOBULIN; IMMUNOGLOBULIN E; PROTEIN SUBUNIT; SEED STORAGE PROTEIN; SOYBEAN PROTEIN;

ADULT; AMINO ACID SEQUENCE; ARTICLE; BLOOD; CHEMISTRY; FOOD ALLERGY; HUMAN; IMMUNOBLOTTING; IMMUNOLOGY; MOLECULAR GENETICS; PLANT SEED; SOYBEAN;

ADULT; ALLERGENS; AMINO ACID SEQUENCE; FOOD HYPERSENSITIVITY; GLOBULINS; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN E; MOLECULAR SEQUENCE DATA; PROTEIN SUBUNITS; SEED STORAGE PROTEINS; SEEDS; SOYBEAN PROTEINS; SOYBEANS;

EID: 61449146289     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf802451g     Document Type: Article

References (31)

1. Messina, M.; Barnes, S. The role of soy products in reducing risk of cancer. J. Natl. Cancer Inst. 1991, 83, 541-546.
2. Montgomery, K. S. Soy protein. J. Perinat. Educ. 2003, 12, 42-45.
3. Food and Drug Administration (FDA). Food Allergen Labeling and Consumer Protection (FALCP) Act of 2004; http://www.cf-san.fda.gov/~acrobat/alrgact.pdf.
4. Cordle, C. T. Soy protein allergy: Incidence and relative severity. Am. Soc. Nutr. Sci. 2004, 134, 1213S-1219S.
5. Zeiger, R. S.; Sampson, H. A.; Bock, S. A.; Burks, A. W.; Harden, K.; Noone, S.; Martin, D.; Leung, S.; Wilson, G. Soy allergy in infants and children with IgE-associated cow's milk allergy. J. Pediatr. 1999, 134, 614-622.
6. Sampson, H. Update on food allergy. Current reviews of allergy and clinical immunology. J. Allergy Clin. Immunol. 2002, 113, 805-819.
7. Sicherer, S. H.; Sampson, H. A. Food allergy. J. Allergy Clin. Immunol. 2006, 117, S470-S475.
8. Wilson, S.; Blaschek, K.; González de Mejia, E. Allergenic proteins in soybean: processing and reduction of P34 allergenicity. Nutr. Rev. 2005, 63, 47-58.
9. Beardslee, T. A.; Zeece, M. G.; Sarath, G.; Markwell, J. P. Soybean glycinin G1 acidic chain shares IgE epitopes with peanut allergen Ara h 3. Int. Arch. Allergy Immunol. 2000, 123, 299-307.
10. Helm, R. M.; Cockrell, G.; Connaughton, C.; Sampson, H. A.; Bannon, G. A.; Beilinson, V.; Livingstone, D.; Nielsen, N. C.; Burks, A. W. A soybean G2 glycinin allergen 1. Identification and characterization. Int. Arch. Allergy Immunol. 2000, 123, 205-212.
11. Ogawa, T.; Tsuji, H.; Bando, N.; Kitamura, K.; Zhu, Y. L.; Hirano, H.; Nishikawa, K. Identification of the soybean allergenic protein, Gly m Bd 30K, with the soybean seed 34-kDa oil-body-associated protein. Biosci., Biotechnol., Biochem. 1993, 57, 1030-1033.
12. Ogawa, A.; Samoto, M.; Takahashi, K. Soybean allergens and hypoallergenic soybean products. J. Nutr. Sci. Vitaminol. 2000, 46, 271-279.
13. Xiang, P.; Beardslee, T. A.; Zeece, M. G.; Markwell, J.; Sarath, G. Identification and analysis of a conserved immunoglobulin E binding epitope in soybean G1a and G2a and peanut Ara h 3 glycinins. Arch. Biochem. Biophys. 2002, 408, 51-57.
14. Shibasaki, M.; Suzuki, S.; Tajima, S.; Nemoto, H.; Kuroume, T. Allergenicity of major component proteins of soybean. Int. Arch. Allergy Appl. Immunol. 1980, 61, 441-448.
15. Bush, R. K.; Schroeckenstein, D.; Meiner-Davis, S.; Balmes, J.; Rempel, D. Soybean flour asthma: detection of allergens by immunoblotting. J. Allergy Clin. Immunol. 1988, 82, 251-255.
16. Thanh, V. H.; Shibasaki, K. β-Conglycinin from soybean proteins. Isolation and immunological and physicochemical properties of the monomeric forms. Biochim. Biophys. Acta 1977, 490, 370-384.
17. Harada, J. J.; Barker, S. J.; Goldberg, R. B. Soybean β-conglycinin genes are clustered in several DNA regions and regulated by transcriptional and posttranscriptional processes. Plant Cell 1989, 1, 415-425.
18. Ogawa, T.; Bando, N.; Tsuji, T.; Nishikawa, K.; Kitamura, K. α-Subunit of β-conglycinin, an allergenic protein recognized by IgE antibodies of soybean-sensitive patients with atopic dermatitis. Biosci., Biotechnol., Biochem. 1995, 59, 831-833.
19. Laemmli, U. K. Cleavage of structure proteins during assembly of the head of bacteriophage. Nature 1970, 227, 680-685.
20. Krishnan, H. B.; Natarajan, S. S.; Mahmoud, A. A.; Bennett, J. O; Krishnan, A, H.; Prasad, B. N. Assessment of indigenous Nepalese soybean as a potential germplasms resource for improvement of protein in North American cultivars. J. Agric. Food Chem. 2006, 54, 5489-5497.
21. Nagano, T.; Hirotsuka, M.; Mori, H.; Kohyama, K.; Nishinari, K. Dynamic viscoelastic study on the gelation of 7S globulin from soybeans. J. Agric. Food Chem. 1992, 40, 941-944.
22. Krishnan, H. B.; Jiang, G.; Krishnan, A. H.; Wiebold, W. J. Seed storage protein composition of non-nodulating soybean (Glycine max (L.) Merr.) and its influence on protein quality. Plant Sci. 2000, 157, 191-199.
23. Fotisch, K.; Vieths, S. N- and O-linked oligosaccharides of allergenic glycoproteins. Glycoconjugate J. 2001, 18, 373-390.
24. Herian, A. M.; Taylor, S. L.; Bush, R, K. Identification of soybean allergens by immunoblotting with sera from soy-allergic adults. Int. Arch. Allergy Appl. Immunol. 1990, 92, 193-198.
25. Ogawa, T.; Bando, N.; Tsuji, H.; Okajima, H.; Nishikawa, K.; Sasaoka, K. Investigation of the IgE-binding proteins in soybeans by immunoblotting with the sera of the soybean-sensitive patients with atopic dermatitis. J. Nutr. Sci. Vitaminol. 1991, 37, 555-565.
26. Gonzalez, R.; Zapatero, L.; Caravaca, F.; Carriera, J. Identification of soybean proteins responsible for respiratory allergies. Int. Arch. Allergy Appl. Immunol. 1991, 95, 53-57.
27. Codina, R.; Lockey, R. F.; Fernandez-Caldas, E.; Rama, R. Identification of the soybean hull allergens responsible fpr the Barcelona asthma outbreak. Int. Arch. Allergy Immunol. 1999, 119, 69-71.
28. Djurtoft, R.; Pedersen, H. S.; Aabin, B.; Bartholt, V. Studies of food allergens: soybean and egg proteins. Adv. Exp. Med. Biol. 1991, 289, 281-293.
29. Zeece, M. G.; Beardslee, T. A.; Markwell, J.; Sarath, G. Identification of an IgE-binding region in soybean acidic glycinin G1. Food Agric. Immunol. 1999, 11, 83-90.
30. Guo, P.; Hao, X.; Ou, D.; Li, D.; Hao, Y. Characterization of the antigenic specificity of soybean protein beta-conglycinin and its effects on growth and immune functions in rats. Arch. Anim. Nutr. 2007, 61, 189-200.
31. Guo, P.; Piao, X.; Cao, Y.; Ou, D.; Li, D. Recombinant soybean protein β-conglycinin α′-subunit expression and induced hypersensitivity reaction in rats. Int. Arch. Allergy Immunol. 2008, 145, 102-110.