Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in human tracheal smooth muscle cells

Free Radical Biology and Medicine

Volumn 46, Issue 7, 2009, Pages 948-960

  Cheng, Shin Ei ^a   Luo, Shue Fen ^a   Jou, Mei Jie ^a   Lin, Chih Chung ^a   Kou, Yu Ru ^b   Lee, I Ta ^a   Hsieh, Hsi Lung ^c   Yang, Chuen Mao ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Cigarette smoke extract; Cytosolic phospholipase A2; Human tracheal smooth muscle cells; MAPKs; Reactive oxygen apecies

Indexed keywords

CIGARETTE SMOKE CONDENSATE; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CIGARETTE SMOKING; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; TRACHEA MUCOSA;

ACETOPHENONES; ACETYLCYSTEINE; BUTADIENES; CELLS, CULTURED; CURCUMIN; CYTOPLASM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE KINASE KINASES; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; NF-KAPPA B; NITRILES; ONIUM COMPOUNDS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A2; RNA, SMALL INTERFERING; SESQUITERPENES; SMOKING; TRACHEA; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 61449087199     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.01.006     Document Type: Article

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