Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferator-activated receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 6, 2009, Pages 1643-1646

  Tsuji, Kiyomi ^a   Satoh, Shigeru ^a   Mitsutake, Susumu ^a   Murakami, Itsuo ^a   Park, Jeong Ju ^b   Li, Qian ^c   Chang, Young Tae ^d   Chung, Sung Kee ^b   Igarashi, Yasuyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Pohang University of Science and Technology (POSTECH)   (South Korea)

^c NEW YORK UNIVERSITY   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Ceramide; PPAR; Reporter assay; Sphingolipid; Transcriptional activation

Indexed keywords

4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; CIGLITAZONE; LUCIFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; SPHINGOLIPID;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; GENE AMPLIFICATION; GENETIC TRANSFECTION; IMMUNOBLOTTING; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; CERAMIDES; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; GENES, REPORTER; LIGANDS; LUCIFERASES; MICE; NIH 3T3 CELLS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PLASMIDS; SPHINGOLIPIDS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 61349157463     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.004     Document Type: Article

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