Phosphorus-32 in the Phage Group: radioisotopes as historical tracers of molecular biology

Studies in History and Philosophy of Science Part C :Studies in History and Philosophy of Biological and Biomedical Sciences

Volumn 40, Issue 1, 2009, Pages 29-42

  Creager, Angela N H ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Bacteriophage; Hershey Chase experiment; Meselson Stahl experiment; Molecular biology; Radiobiology; Radioisotopes; Suicide experiments; Target theory; United States Atomic Energy Commission (AEC)

Indexed keywords

PHOSPHORUS;

ARTICLE; BACTERIOPHAGE; HISTORY; ISOTOPE LABELING; MOLECULAR BIOLOGY; NUCLEAR ENERGY; PHOTOSYNTHESIS; UNITED STATES;

BACTERIOPHAGES; HISTORY, 20TH CENTURY; ISOTOPE LABELING; MOLECULAR BIOLOGY; NUCLEAR ENERGY; PHOSPHORUS RADIOISOTOPES; PHOTOSYNTHESIS; UNITED STATES;

EID: 61349157271     PISSN: 13698486     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.shpsc.2008.12.005     Document Type: Article

References (134)

1. Abir-Am P.G. Themes, genres and order of legitimation in the consolidation of new scientific disciplines: Deconstructing the historiography of molecular biology. History of Science 23 (1985) 72-117
2. Anderson T.F. Techniques for the preservation of three-dimensional structure in preparing specimens for the electron microscope. Transactions of the New York Academy of Sciences 13 (1951) 130-134
3. Appelmans R. Quelques applications de la méthode de dosage du bactériophage. Comptes rendus de l'Académie des Sciences, Paris 86 (1922) 508-509
4. Baird D. Thing knowledge: A philosophy of scientific instruments (2004), University of California Press, Berkeley, CA
5. Barker, C. R. C. (2008). From atom bomb to the 'genetic time bomb': Telomeres, aging, and cancer in the era of molecular biology. Ph.D. dissertation, Yale University.
6. Beatty, J. (1999). Genetics and the state. Unpublished paper presented at Penn-Princeton Workshop, 27 February 1999.
7. Benzer S. Resistance to ultraviolet light as an index to the reproduction of bacteriophage. Journal of Bacteriology 63 (1952) 59-72
8. Bocking S. Ecologists and environmental politics: A history of contemporary ecology (1997), Yale University Press, New Haven, CT
9. Brock T.D. The emergence of bacterial genetics (1990), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
10. Cairns J. An estimate of the length of the DNA molecule of T2 bacteriophage by autoradiography. Journal of Molecular Biology 3 (1961) 756-761
11. Cairns J. The bacterial chromosome and its manner of replication as seen by autoradiography. Journal of Molecular Biology 6 (1963) 208-213
12. Cairns J., Stent G.S., and Watson J.D. Phage and the origins of molecular biology (1966), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
13. Carlson E.A. Genes, radiation, and society: The life and work of H. J. Muller (1981), Cornell University Press, Ithaca, NY
14. Creager A.N.H. The life of a virus: Tobacco mosaic virus as an experimental model, 1930-1965 (2002), University of Chicago Press, Chicago, IL
15. Creager, A. N. H. (2004). The industrialization of radioisotopes by the U.S. Atomic Energy Commission. In K. Grandin, N. Wormbs, & S. Widmalm (Eds.), The science-industry nexus: History, policy, implications. Proceedings of Nobel Symposium 123 (pp. 141-167). Sagamore Beach, MA: Science History Publications, 2004.
16. Creager A.N.H. Nuclear energy in the service of biomedicine: The U.S. Atomic Energy Commission's radioisotope program, 1946-1950. Journal of the History of Biology 39 (2006) 649-684
17. Creager A.N.H., and Santesmases M.J. Radiobiology in the atomic age: Changing research practices and policies in comparative perspective. Journal of the History of Biology 39 (2006) 637-647
18. Crowther, J. A. (1924). Some considerations relative to the action of X-rays on tissue cells. Proceedings of the Royal Society of London: Series B, Containing Papers of a Biological Character, 96, 207-211.
19. de Chadarevian S. Designs for life: Molecular biology after World War II (2002), Cambridge University Press, Cambridge
20. de Chadarevian S. Mice and the reactor: The 'genetics experiment' in 1950s Britain. Journal of the History of Biology 39 (2006) 707-735
21. Dekker, C. A., & Schachman, H. K. (1954). On the macromolecular structure of deoxyribonucleic acid: An interrupted two-strand model. Proceedings of the National Academy of Sciences, USA, 40, 894-909.
22. Delbrück M. Experiments with bacterial viruses (bacteriophages). Harvey Lectures 41 (1946) 161-187
23. Delbrück M., and Luria S.E. Interference between bacterial viruses. Part 1. Interference between two bacteria viruses acting upon the same host, and the mechanism of virus growth. Archives of Biochemistry 1 (1942) 111-141
24. Delbrück, M., & Stent, G. S. (1957). On the mechanism of DNA replication. In W. D. McElroy, & B. Glass (Eds.), The Chemical Basis of Heredity (pp. 699-736). Baltimore: Johns Hopkins University Press.
25. Doermann, A. H., Chase, M., & Stahl, F. W. (1955). Genetic recombination and replication in bacteriophage. Journal of Cellular and Comparative Physiology, 45, Suppl. 2, 51-74.
26. Dulbecco R. Experiments on photoreactivation of bacteriophages inactivated with ultraviolet radiation. Journal of Bacteriology 59 (1950) 329-347
27. Echols, H. (2001). Operators and promoters: The story of molecular biology and its creators (C. A. Gross, Ed.). Berkeley, CA: University of California Press.
28. Elzen B. Two ultracentrifuges: A comparative study of the social construction of artefacts. Social Studies of Science 16 (1986) 621-662
29. Fuerst C.R., Jacob F., and Wollman E.L. Détermination de liaisons génétiques, chez Escherichia coli K12, à l'aide de radiophosphore. Comptes rendus de l'Académie des Sciences 243 (1956) 2162-2164
30. Fuerst C.R., and Stent G.S. Inactivation of bacteria by decay of incorporated radioactive phosphorus. Journal of General Physiology 40 (1956) 73-90
31. Galison P. Image and logic: A material culture of microphysics (1997), University of Chicago Press, Chicago
32. Gaudillière, J.-P. (2002). Inventer la biomédecine: La France, l'Amérique et la production des savoirs du vivant (1945-1965). Paris: Éditions la Découverte.
33. Gaudillière J.-P. Normal pathways: Controlling isotopes and building biomedical research in postwar France. Journal of the History of Biology 39 (2006) 737-764
34. Gaudillière J.-P., and Löwy I. The invisible industrialist: Manufactures and the production of scientific knowledge (1998), Macmillan, London
35. 32P-decay 'suicide' of bacteriophage. Photosynthesis Research 74 (2002) 331-339
36. Gildemeister E. Weitere Untersuchungen über das d'Herellesche Phänomen. Zentralblatt für Bakteriologie, Parasitenkunde und Infektionskrankheiten (I) 89 (1923) 181-186
37. Hagen J.B. An entangled bank: The origins of ecosystem ecology (1992), Rutgers University Press, New Brunswick, NJ
38. Hayes W. The genetics of bacteria and their viruses: Studies in basic genetics and molecular biology (1964), John Wiley & Sons, New York
39. Herran N. Spreading nucleonics: The Isotope School at the Atomic Energy Research Establishment, 1951-67. British Journal for the History of Science 39 (2006) 569-586
40. Herriott R.M. Nucleic-acid-free T2 virus 'ghosts' with specific biological action. Journal of Bacteriology 61 (1951) 752-754
41. Hershey A.D. Reproduction of bacteriophage. International Review of Cytology-A Survey of Cell Biology 1 (1952) 119-134
42. Hershey A.D. Intracellular phases in the reproductive cycle of bacteriophage T2. Annales de l'Institut Pasteur 84 (1953) 99-111
43. Hershey A.D. Conservation of nucleic acids during bacterial growth. Journal of General Physiology 38 (1954) 145-148
44. Hershey, A. D. (1966). The injection of DNA into cells by phage. In J. Cairns, G. S. Stent, & J. D. Watson (Eds.), Phage and the origins of molecular biology (pp. 100-108). Cold Spring Harbor, NY: Cold Spring Harbor University Press.
45. Hershey A.D., and Burgi E. Genetic significance of the transfer of nucleic acid from parental to offspring phage. Cold Spring Harbor Symposia for Quantitative Biology 21 (1956) 91-101
46. Hershey A.D., and Chase M. Independent functions of viral protein and nucleic acid in growth of bacteriophage. Journal of General Physiology 36 (1952) 39-56
47. Hershey A.D., Kamen M.D., Kennedy J.W., and Gest H. The mortality of bacteriophage containing assimilated radioactive phosphorus. Journal of General Physiology 34 (1951) 305-319
48. Hershey, A. D., Roesel, C, Chase, M., & Forman, S. (1951). Growth and inheritance in bacteriophage. Year Book, Carnegie Institution of Washington, 50, 195-200. (Reprinted in F. Stahl (Ed.), We can sleep later: Alfred D. Hershey and the origins of molecular biology (pp. 173-178). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2000)
49. Holmes F.L. Meselson, Stahl, and the replication of DNA: A history of 'the most beautiful experiment in biology' (2001), Yale University Press, New Haven, CT
50. Holmes, F. L. (2006). Reconceiving the gene: Seymour Benzer's adventures in phage genetics (W. C. Summers, Ed.). New Haven, CT: Yale University Press.
51. Hutchinson G.E. Review: Bio-ecology. Ecology 21 (1940) 267-268
52. Hutchinson G.E., and Bowen V.T. A direct demonstration of the phosphorus cycle in a small lake. Proceedings of the National Academy of Sciences, USA 33 (1947) 148-153
53. Hutchinson G.E., and Bowen V.T. Limnological studies in Connecticut. IX. A quantitative radiochemical study of the phosphorus cycle in Linsley Pond. Ecology 31 (1950) 194-203
54. Jacob, F., & Wollman, E. L. (1957). Genetic aspects of lysogeny. In W. D. McElroy, & B. Glass (Eds.), The Chemical Basis of Heredity (pp. 468-499). Baltimore: Johns Hopkins University Press.
55. Jacob F., and Wollman E.L. Sexuality and the genetics of bacteria (1961), Academic Press, New York
56. Jolly, J. C. (2004). Thresholds of uncertainty: Radiation and responsibility in the fallout controversy. Ph.D. dissertation, Oregon State University.
57. Judson H.F. The eighth day of creation: Makers of the revolution in biology (1979), Simon and Schuster, New York
58. Kamen M.D. Radioactive tracers in biology: An introduction to tracer methodology (1951), Academic Press, New York
59. Kamen M.D. Early history of carbon-14. Science 140 (1963) 584-590
60. Kamen M.D. Radiant science, dark politics: A memoir of the nuclear age (1985), University of California Press, Berkeley
61. Kay L.E. Laboratory technology and biological knowledge: The Tiselius electrophoresis apparatus, 1930-1945. History and Philosophy of the Life Sciences 10 (1988) 51-72
62. Kay L.E. The molecular vision of life: Caltech, the Rockefeller Foundation, and the rise of the new biology (1993), Oxford University Press, New York
63. Keller E.F. Physics and the emergence of molecular biology: A history of cognitive and political synergy. Journal of the History of Biology 23 (1990) 389-409
64. Keller, E. F. (1992). From secrets of life to secrets of death. In idem, Secrets of life. Secrets of death: Essays on language, gender and science (pp. 39-55). New York: Routledge.
65. Kevles, D. J., & Geison, G. L. (1995). The experimental life sciences in the twentieth century. Osiris, 10, 97-121, 233-241.
66. Kohler R.E. Partners in science: Foundations and natural scientists, 1900-1945 (1991), University of Chicago Press, Chicago
67. Kohman T.P. Proposed new word: nuclide. American Journal of Physics 15 (1947) 356-357
68. Kopp C. The origins of the American scientific debate over fallout hazards. Social Studies of Science 9 (1979) 403-422
69. Kozloff L.M. Biochemical studies of virus reproduction. VII. The appearance of parent nitrogen and phosphorus in the progeny. Journal of Biological Chemistry 194 (1952) 95-108
70. 6 bacteriophage system. Journal of Biological Chemistry 182 (1950) 229-242
71. Kraft A. Between medicine and industry: Medical physics and the rise of the radioisotope 1945-65. Contemporary British History 20 (2006) 1-35
72. Krige J. The politics of phophorus-32: A cold war fable based on fact. Historical Studies in the Physical and Biological Sciences 36/1 (2005) 71-91
73. Lea D.E. Action of radiations on living cells (1947), Macmillan, New York
74. Lenoir, T., & Hays, M. (2000). The Manhattan Project for biomedicine. In P. R. Sloan (Ed.), Controlling our destinies: Historical, philosophical, ethical, and theological perspectives on the Human Genome Project (pp. 29-62). Notre Dame, IN: University of Notre Dame Press.
75. Levinthal C. The mechanism of DNA replication and genetic recombination in phage. Proceedings of the National Academy of Sciences, USA 42 (1956) 394-404
76. Levinthal, C, & Thomas, C. A., Jr. (1957a). Molecular autoradiography: The β-ray counting from single virus particles and DNA molecules in nuclear emulsions. Biochimica et Biophysica Acta, 23, 453-465.
77. Levinthal, C, & Thomas. C. A., Jr. (1957b). The molecular basis of genetic recombination in phage. In W. D. McElroy, & B. Glass (Eds.), The Chemical Basis of Heredity (pp. 737-755). Baltimore: Johns Hopkins University Press.
78. Lindee Susan M. Suffering made real: American science and the survivors at Hiroshima (1994), University of Chicago Press, Chicago
79. Luria S.E. Reactivation of irradiated bacteriophage by transfer of self- reproducing units. Proceedings of the National Academy of Sciences, USA 33 (1947) 253-264
80. Luria, S. E. (1952). Reactivation of ultraviolet-irradiated bacteriophage by multiple infection. Journal of Cellular and Comparative Physiology, 39, Supp. 1, 119-123.
81. Luria, S. E. (1955). Radiation and viruses. In A. Hollaender (Ed.), Radiation biology. Vol. II: Ultraviolet and related radiations (pp. 333-364), New York: McGraw-Hill.
82. Luria S.E., and Latarjet R. Ultraviolet irradiation of bacteriophage during intracellular growth. Journal of Bacteriology 53 (1947) 149-163
83. Maaløe O., and Stent G.S. Radioactive phosphorus tracer studies on the reproduction of T4 bacteriophage. I. Intracellular appearance of phage-like material. Acta pathologica et microbiologica Scandinavica 30 (1952) 149-157
84. Maaløe O., and Watson J.D. The transfer of radioactive phosphorus from parental to progeny phage. Proceedings of the National Academy of Sciences, USA 37 (1951) 507-513
85. Meselson, M., & Stahl, F. W. (1958). 'The replication of DNA in Escherichia coli,' Proceedings of the National Academy of Science USA, 44, 671-682.
86. Olby, R. C. (1994). The path to the double helix: The discovery of DNA. New York: Dover. (First published 1974)
87. Pasveer B. Knowledge of shadows: The introduction of X-ray images in medicine. Sociology of Health & Illness 11 (1989) 360-381
88. Peyrieras N., and Morange M. The study of lysogeny at the Pasteur Institute (1950-1960): An epistemologically open system. Studies in History and Philosophy of Biological and Biomedical Sciences 33C (2002) 419-430
89. Pickering A. The mangle of practice: Time, agency, and science (1995), University of Chicago Press, Chicago
90. Pollard, E. C, & Forro, F., Jr. (1949). Examination of the target theory by deuteron bombardment of T-1 phage. Science, 109, 374-375 & 386.
91. Pontecorvo G. Genetic formulation of gene structure and gene action. Advances in Enzymology 13 (1952) 121-149
92. Putnam F.W., and Kozloff L.M. On the origin of virus phosphorus. Science 108 (1948) 386-387
93. Putnam F.W., and Kozloff L.M. Biochemical studies of virus reproduction. IV. The fate of the infecting virus particle. Journal of Biological Chemistry 182 (1950) 243-250
94. Rader K.A. Making mice: Standardizing animals for American biomedical research, 1900-1955 (2004), Princeton University Press, Princeton, NJ
95. Rader K.A. Alexander Hollaender's postwar vision for biology: Oak Ridge and beyond. Journal for the History of Biology 39 (2006) 685-706
96. Rainger, R. (2004). 'A wonderful oceanographic tool': The atomic bomb, radioactivity, and the development of American oceanography. In H. M. Rozwadowski, & D. K. van Keuren (Eds.), The machine in Neptune's garden: Historical perspectives on technology and the marine environment (pp. 93-131). Sagamore Beach, MA: Science History Publications.
97. Rasmussen N. Picture control: The electron microscope and the transformation of biology in America, 1940-1960 (1997), Stanford University Press, Stanford, CA
98. Rasmussen N. The mid-century biophysics bubble: Hiroshima and the biological revolution in America, revisited. History of Science 35 (1997) 245-293
99. Rheinberger H.-J. Toward a history of epistemic things: Synthesizing proteins in the test tube (1997), Stanford University Press, Stanford, CA
100. Rheinberger, H.-J. (2001). Putting isotopes to work: Liquid scintillation counters, 1950-1970. In B. Joerges, & T. Shinn (Eds.), Instrumentation: Between science, state and industry (pp. 143-174). Dordrecht: Kluwer Academic Publishing.
101. Rheinberger, H.-J. (n.d. a) Experimental readings. (unpublished)
102. Rheinberger, H.-J. (n.d. b) In vitro. (unpublished)
103. Ruben S. Photosynthesis and phosphorylation. Journal of the American Chemical Society 65 (1943) 279-282
104. Santesmases M.J. Peace propaganda and biomedical experimentation: Influential uses of radioisotopes in endocrinology and molecular genetics in Spain (1947-1971). Journal of the History of Biology 39 (2006) 765-794
105. Shapin S. The invisible technician. American Scientist 77 (1989) 554-563
106. Sloan, P. R., & Fogel, B. (Under review). The three-man paper and the origins of molecular biology. Chicago: University of Chicago Press.
107. Stahl F.W. The effects of the decay of incorporated radioactive phosphorus on the genome of bacteriophage T4. Virology 2 (1956) 206-234
108. Stahl, F. W. (1959). Radiobiology of bacteriophage. In F. M. Burnet, & W. M. Stanley (Eds.), The viruses: Biochemical, biological, and biophysical properties. Volume 2: Plant and bacterial viruses (pp. 353-385). New York: Academic Press.
109. Stahl F.W. We can sleep later: Alfred D. Hershey and the origins of molecular biology (2000), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
110. Stent G.S. Mortality due to radioactive phosphorus as an index to bacteriophage development. Cold Spring Harbor Symposia on Quantitative Biology 18 (1953) 255-259
111. Stent G.S. Cross reactivation of genetic loci of T2 bacteriophage after decay of incorporated radioactive phosphorus. Proceedings of the National Academy of Sciences, USA 39 (1953) 1234-1241
112. Stent G.S. Decay of incorporated radioactive phosphorus during reproduction of bacteriophage T2. Journal of General Physiology 38 (1955) 853-865
113. Stent G.S. Molecular biology of bacterial viruses (1963), W. H. Freeman, San Francisco, CA
114. Stent G.S. Molecular genetics: An introductory narrative (1971), W. H. Freeman, San Francisco, CA
115. Stent G.S., and Fuerst C.R. Inactivation of bacteriophages by decay of incorporated radioactive phosphorus. Journal of General Physiology 38 (1955) 441-458
116. Stent G.S., and Fuerst C.R. Decay of incorporated radioactive phosphorus during development of a temperate bacteriophage. Virology 2 (1956) 737-752
117. Stent G.S., Fuerst C.R., and Jacob F. Inactivation d'un prophage par la désintégration du radiophosphore. Comptes rendus de l'Académie des Sciences 244 (1957) 1840-1842
118. Stent G.S., and Jerne N. The distribution of parental phosphorus atoms among bacteriophage progeny. Proceedings of the National Academy of Sciences, USA 41 (1955) 704-709
119. Stent G.S., Sato G.H., and Jerne N.K. Dispersal of the parental nucleic acid of bacteriophage T4 among its progeny. Journal of Molecular Biology 1 (1959) 134-146
120. Strasser, B. J. (2006). La fabrique d'une nouvelle science: La biologie moléculaire à l′âge atomique (1945-1964). Florence: Leo S. Olschki.
121. Strasser, B. J. (n.d.). Restriction enzymes in the atomic age. (unpublished)
122. Summers, W. C. (1995). Concept migration: The case of target theories in physics and biology. Paper presented at History of Science Society meeting, Minneapolis.
123. Summers, W. C. (2002). Molecular biophysics. In S. Altman (Ed.), Science at Yale (pp. 199-206). New Haven: Yale University Press.
124. Szybalski, W. (2000). In memoriam: Alfred D. Hershey (1908-1997). In F. Stahl (Ed.), (2000). We can sleep later: Alfred D. Hershey and the origins of molecular biology (pp. 19-22). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
125. 32 into ribonucleic acid at the intracellular level. Experimental Cell Research 9 (1955) 460-473
126. Taylor J.H., Woods P.S., and Hughes W.L. The organization and duplication of chromosomes as revealed by autoradiographic studies using tritium-labeled thymidine. Proceedings of the National Academy of Sciences, USA 43 (1957) 122-128
127. United States Atomic Energy Commission (1948). Fourth semiannual report to Congress. Washington, DC: US Government Printing Office.
128. United States Atomic Energy Commission (1955). Eight-year isotope summary. Selected reference material, United States Atomic Energy Program, Vol. 7. Washington, DC: US Government Printing Office.
129. Watanabe I., Stent G.S., and Schachman H.S. On the state of the parental phosphorus during reproduction of bacteriophage T2. Biochimica et Biophysica Acta 15 (1954) 38-49
130. Watson J.D., and Crick F.H.C. A structure for deoxyribose nucleic acid. Nature 171 (1953) 737-738
131. Watson J.D., and Crick F.H.C. Genetical implications of the structure of deoxyribose nucleic acid. Nature 171 (1953) 964-967
132. Wyatt H.V. How history has blended. Nature 249 (1974) 803-804
133. Yi, D. (2007). The coming of reversibility: The discovery of DNA repair between the atomic age and the information age. Historical Studies in the Physical and Biological Sciences, 37, Supplement, 35-72.
134. Zallen D.T. The Rockefeller Foundation and spectroscopy research: The programs at Chicago and Utrecht. Journal of the History of Biology 25 (1992) 67-89