Targeting delivery oligonucleotide into macrophages by cationic polysaccharide from Bletilla striata successfully inhibited the expression of TNF-α

Journal of Controlled Release

Volumn 134, Issue 3, 2009, Pages 214-220

  Dong, Lei ^a   Xia, Suhua ^a   Luo, Yi ^a   Diao, Huajia ^a   Zhang, Jiani ^a   Chen, Jiangning ^a   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Bletilla striata; Cationic polysaccharide; Mannose receptor; Oligonucleotide; Targeting delivery

Indexed keywords

ANTI-INFLAMMATORY; ANTISENSE; BINDING AFFINITIES; BLETILLA STRIATA; CARBONYLDIIMIDAZOLE; CATIONIC POLYSACCHARIDE; CATIONIZED; CELL THERAPIES; ETHYLENEDIAMINE; GENE CARRIERS; GLUCOMANNAN; GLUCOSE RESIDUES; HIGH AFFINITIES; MANNOSE RECEPTOR; MULTIPLE CELL TYPES; NATURAL BIOPOLYMERS; OLIGODEOXYNUCLEOTIDE; SMALL INTERFERENCE RNAS; STABLE COMPLEXES; TARGET GENE EXPRESSIONS; TARGETING DELIVERY;

BINDING ENERGY; BIOACTIVITY; BIOPOLYMERS; DYES; ELECTROPHORETIC MOBILITY; GENE EXPRESSION; GENE TRANSFER; GLUCOSE; MACROPHAGES; OLIGONUCLEOTIDES; POLYMERS; POLYSACCHARIDES; RNA;

NUCLEIC ACIDS;

ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; BETA GLUCAN; BLETILLA STRIATA POLYSACCHARIDE; CATION; DNA; ETHYLENEDIAMINE; ISIS 28383; MANNAN; MANNOSE; MANNOSE RECEPTOR; POLYSACCHARIDE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLETILLA STRIATA; CELL SURFACE; CELL TYPE; CELL VIABILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG TARGETING; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; LIGAND BINDING; MACROPHAGE; MOUSE; NANOANALYSIS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; ORCHIDACEAE; PARTICLE SIZE; PRIORITY JOURNAL; TOXICITY TESTING;

ANIMALS; CATIONS; CELL SURVIVAL; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; LECTINS, C-TYPE; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; NANOPARTICLES; ORCHIDACEAE; PARTICLE SIZE; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; POLYSACCHARIDES; PROTEIN BINDING; RECEPTORS, CELL SURFACE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 61349144250     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.11.013     Document Type: Article

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