A polysaccharide isolated from the medicinal herb Bletilla striata induces endothelial cells proliferation and vascular endothelial growth factor expression in vitro

Biotechnology Letters

Volumn 28, Issue 8, 2006, Pages 539-543

  Wang, Chunming ^a   Sun, Jiantao ^a,b   Luo, Yi ^a   Xue, Weihua ^a   Diao, Huajia ^a   Dong, Lei ^a   Chen, Jiangning ^a   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Bletilla striata; Cell proliferation; Endothelial cells; Polysaccharides; Vascular endothelial growth factor

Indexed keywords

BLETILLA STRIATA; CELL PROLIFERATION; ENDOTHELIAL CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR;

CELL CULTURE; GROWTH KINETICS; MEDICINE; PURIFICATION;

POLYSACCHARIDES;

GALACTOSE; GLUCOSE; MANNOSE; POLYSACCHARIDE; VASCULOTROPIN A; XYLOSE;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFRARED SPECTROSCOPY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORCHIDACEAE; TIME;

CELL PROLIFERATION; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GALACTOSE; GLUCOSE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MANNOSE; MOLECULAR STRUCTURE; ORCHIDACEAE; PLANTS, MEDICINAL; POLYSACCHARIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XYLOSE;

BLETILLA STRIATA;

EID: 33645865532     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-006-0011-x     Document Type: Article

References (14)

1. P Agrawal 1992 NMR spectroscopy in the structure elucidation of oligosaccharide and glycosides Phytochemistry 31 3307 3330
2. N Blumenkrantz G Asboe-Hansen 1973 New method for quantitative determination of uronic acids Anal. Biochem. 54 484 489
3. MF Chaplin JF Kennedy 1994 Carbohydrate Analysis: A Practical Approach 2 Oxford University Press Oxford
4. MR Cominetti CHB Terruggi OHP Ramos 2004 Alternagin-C, a disintegrin-like protein, induces VEGF expression and endothelial cell proliferation in vitro J. Biol. Chem. 279 18247 18255
5. EA Jaffe RL Nachman CG Becker CR Minick 1973 Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria J. Clin. Invest. 52 2745 2756
6. A Kawada N Hiura S Tajima H Takahara 1999 Alginate oligosaccharides stimulated VEGF-mediated growth and migration of human endothelial cells Arch. Dermatol. Res. 291 542 547
7. H Kawagishi A Nomura T Mizuno A Kimura S Chiba 1990 Isolation and characterization of a lectin from Grifola frondosa fruiting bodies Biochim. Biophys. Acta 1034 247 252
8. M Mathlouthi J Koenig 1986 Vibrational spectra of carbohydrate Adv. Carbohydr. Chem. Biochem. 44 7 89
9. S Matou S Colliec-Jounault I Galy-Fauroux 2005 Effect of an oversulfated exopolysaccharide on angiogenesis induced by fibroblast growth factor-2 or vascular endothelial growth factor in vitro Biochem. Pharmacol. 69 751 759
10. W Risau 1997 Mechanisms of angiogenesis Nature 386 671 674
11. M Tomoda S Nakatsuka M Tamai M Nagata 1973 Isolation and characterization of a mucous polysaccharide, Bletilla-glucomannan from Bletilla striata tubers Chem. Pharm. Bull. 21 2667 2671
12. S Wang Z Zheng Y Weng Y Yu D Zhang W Fan R Dai Z Hu 2004 Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts Life Sci. 74 2467 2478
13. S Yamagishi T Kawakami H Fujimori H Yonekura N Tanaka 1999 Insulin stimulates the growth and tube formation of human microvascular endothelial cells through autocrine VEGF Microvasc. Res. 57 329 339
14. Y Ye M Koo Y Li H Matsui C Cho 2001 Angelica sinensis modulates migration and proliferation of gastric epithelial cells Life Sci. including Pharm. Lett. 68 961 968