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Volumn 63, Issue SUPPL. 1, 2009, Pages

Recommendations from the Spanish oncology genitourinary group for the treatment of metastatic renal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; ANTIHYPERTENSIVE AGENT; BEVACIZUMAB; CALCIUM; CREATININE; EVEROLIMUS; HYPERTENSIVE FACTOR; HYPOXIA INDUCIBLE FACTOR; INTERLEUKIN 2; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MEDROXYPROGESTERONE ACETATE; SORAFENIB; SUNITINIB; TEMSIROLIMUS;

EID: 61349134778     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-009-0955-3     Document Type: Conference Paper
Times cited : (9)

References (81)
  • 2
    • 2342617539 scopus 로고    scopus 로고
    • Risk factors for adult renal cell carcinoma
    • R Dhote N Thiounn B Debre 2004 Risk factors for adult renal cell carcinoma Urol Clin N Am 31 237 247
    • (2004) Urol Clin N Am , vol.31 , pp. 237-247
    • Dhote, R.1    Thiounn, N.2    Debre, B.3
  • 3
    • 10744223370 scopus 로고    scopus 로고
    • Tobacco and cancer: Recent epidemiological evidence
    • P Vineis M Alavanja P Buffler 2004 Tobacco and cancer: recent epidemiological evidence J Natl Cancer Inst 96 99 106
    • (2004) J Natl Cancer Inst , vol.96 , pp. 99-106
    • Vineis, P.1    Alavanja, M.2    Buffler, P.3
  • 4
    • 0034597647 scopus 로고    scopus 로고
    • Obesity, hypertension, and the risk of kidney cancer in men
    • WH Chow G Gridley JF Fraumeni Jr 2000 Obesity, hypertension, and the risk of kidney cancer in men N Engl J Med 343 1305 1311
    • (2000) N Engl J Med , vol.343 , pp. 1305-1311
    • Chow, W.H.1    Gridley, G.2    Fraumeni Jr, J.F.3
  • 5
    • 0033918360 scopus 로고    scopus 로고
    • Risk factors for adult renal cell carcinoma: A systematic review and implications for prevention
    • R Dhote M Pellicer-Coeuret N Thiounn 2000 Risk factors for adult renal cell carcinoma: a systematic review and implications for prevention BJU Int 86 20 27
    • (2000) BJU Int , vol.86 , pp. 20-27
    • Dhote, R.1    Pellicer-Coeuret, M.2    Thiounn, N.3
  • 6
    • 33749598631 scopus 로고    scopus 로고
    • New horizons in the treatment of renal cell cancer
    • Suppl 10
    • J Wagstaff 2006 New horizons in the treatment of renal cell cancer Ann Oncol 17 Suppl 10 x19 x22
    • (2006) Ann Oncol , vol.17
    • Wagstaff, J.1
  • 7
    • 33846866256 scopus 로고    scopus 로고
    • Innovations and challenges in renal cell carcinoma: Summary statement from the Second Cambridge Conference
    • MB Atkins MS Ernstoff RA Figlin 2007 Innovations and challenges in renal cell carcinoma: summary statement from the Second Cambridge Conference Clin Cancer Res 13 667s 670s
    • (2007) Clin Cancer Res , vol.13
    • Atkins, M.B.1    Ernstoff, M.S.2    Figlin, R.A.3
  • 8
    • 33644510421 scopus 로고    scopus 로고
    • Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer
    • RE Banks P Tirukonda C Taylor 2006 Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer Cancer Res 66 2000 2011
    • (2006) Cancer Res , vol.66 , pp. 2000-2011
    • Banks, R.E.1    Tirukonda, P.2    Taylor, C.3
  • 9
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
    • L Schmidt FM Duh F Chen 1997 Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas Nat Genet 16 68 73
    • (1997) Nat Genet , vol.16 , pp. 68-73
    • Schmidt, L.1    Duh, F.M.2    Chen, F.3
  • 10
    • 21044457377 scopus 로고    scopus 로고
    • Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome
    • LS Schmidt ML Nickerson MB Warren 2005 Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome Am J Hum Genet 76 1023 1033
    • (2005) Am J Hum Genet , vol.76 , pp. 1023-1033
    • Schmidt, L.S.1    Nickerson, M.L.2    Warren, M.B.3
  • 12
    • 62549111051 scopus 로고    scopus 로고
    • Springer New York
    • Greene FL, Page DL, Fleming ID et al (2002) AJCC cancer staging handbook: TNM classification of malignant tumors. Springer, New York
    • (2002)
    • Greene, F.L.1    Page, D.L.2    Fleming, I.D.3
  • 13
    • 27744561283 scopus 로고    scopus 로고
    • Renal cell carcinoma: Current status and future prospects
    • BJ Drucker 2005 Renal cell carcinoma: current status and future prospects Cancer Treat Rev 31 536 545
    • (2005) Cancer Treat Rev , vol.31 , pp. 536-545
    • Drucker, B.J.1
  • 14
    • 0028928669 scopus 로고
    • Renal cell carcinoma: Tumor size, stage and survival. Members of the Cancer Incidence and End Results Committee
    • PD Guinan NJ Vogelzang AM Fremgen 1995 Renal cell carcinoma: tumor size, stage and survival. Members of the Cancer Incidence and End Results Committee J Urol 153 901 903
    • (1995) J Urol , vol.153 , pp. 901-903
    • Guinan, P.D.1    Vogelzang, N.J.2    Fremgen, A.M.3
  • 15
    • 4644219959 scopus 로고    scopus 로고
    • Laparoscopic and partial nephrectomy
    • AC Novick 2004 Laparoscopic and partial nephrectomy Clin Cancer Res 10 6322S 6327S
    • (2004) Clin Cancer Res , vol.10
    • Novick, A.C.1
  • 16
    • 38049088347 scopus 로고    scopus 로고
    • Renal cell carcinoma: New developments in molecular biology and potential for targeted therapies
    • LJ Costa HA Drabkin 2007 Renal cell carcinoma: new developments in molecular biology and potential for targeted therapies Oncologist 12 1404 1415
    • (2007) Oncologist , vol.12 , pp. 1404-1415
    • Costa, L.J.1    Drabkin, H.A.2
  • 17
    • 0035818877 scopus 로고    scopus 로고
    • Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
    • RC Flanigan SE Salmon BA Blumenstein 2001 Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer N Engl J Med 345 1655 1659
    • (2001) N Engl J Med , vol.345 , pp. 1655-1659
    • Flanigan, R.C.1    Salmon, S.E.2    Blumenstein, B.A.3
  • 18
    • 0035934596 scopus 로고    scopus 로고
    • Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: A randomised trial
    • GH Mickisch A Garin H van Poppel 2001 Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial Lancet 358 966 970
    • (2001) Lancet , vol.358 , pp. 966-970
    • Mickisch, G.H.1    Garin, A.2    Van Poppel, H.3
  • 19
    • 34047222738 scopus 로고    scopus 로고
    • Recent progress in the management of advanced renal cell carcinoma
    • JA Garcia BI Rini 2007 Recent progress in the management of advanced renal cell carcinoma CA Cancer J Clin 57 112 125
    • (2007) CA Cancer J Clin , vol.57 , pp. 112-125
    • Garcia, J.A.1    Rini, B.I.2
  • 21
    • 20744433084 scopus 로고    scopus 로고
    • Surgical intervention in patients with metastatic renal cancer: Current status of metastasectomy and cytoreductive nephrectomy
    • P Russo 2004 Surgical intervention in patients with metastatic renal cancer: current status of metastasectomy and cytoreductive nephrectomy Nat Clin Pract Urol 1 26 30
    • (2004) Nat Clin Pract Urol , vol.1 , pp. 26-30
    • Russo, P.1
  • 22
    • 33846698219 scopus 로고    scopus 로고
    • Patients with metastatic renal cell carcinoma with long-term disease-free survival after treatment with sunitinib and resection of residual metastases
    • BI Rini V Shaw JE Rosenberg 2006 Patients with metastatic renal cell carcinoma with long-term disease-free survival after treatment with sunitinib and resection of residual metastases Clin Genitourin Cancer 5 232 234
    • (2006) Clin Genitourin Cancer , vol.5 , pp. 232-234
    • Rini, B.I.1    Shaw, V.2    Rosenberg, J.E.3
  • 23
    • 0015837537 scopus 로고
    • The value of radiotherapy in the treatment of hypernephroma-a clinical trial
    • R Finney 1973 The value of radiotherapy in the treatment of hypernephroma-a clinical trial Br J Urol 45 258 269
    • (1973) Br J Urol , vol.45 , pp. 258-269
    • Finney, R.1
  • 24
    • 0017671905 scopus 로고
    • Preoperative irradiation in the treatment of renal adenocarcinoma
    • H Juusela K Malmio O Alfthan 1977 Preoperative irradiation in the treatment of renal adenocarcinoma Scand J Urol Nephrol 11 277 281
    • (1977) Scand J Urol Nephrol , vol.11 , pp. 277-281
    • Juusela, H.1    Malmio, K.2    Alfthan, O.3
  • 25
    • 0023219487 scopus 로고
    • Postoperative radiotherapy in stage II and III renal adenocarcinoma. A randomized trial by the Copenhagen Renal Cancer Study Group
    • M Kjaer PL Frederiksen SA Engelholm 1987 Postoperative radiotherapy in stage II and III renal adenocarcinoma. A randomized trial by the Copenhagen Renal Cancer Study Group Int J Radiat Oncol Biol Phys 13 665 672
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 665-672
    • Kjaer, M.1    Frederiksen, P.L.2    Engelholm, S.A.3
  • 26
    • 0023553094 scopus 로고
    • A randomized trial of postoperative radiotherapy versus observation in stage II and III renal adenocarcinoma. A study by the Copenhagen Renal Cancer Study Group
    • M Kjaer P Iversen V Hvidt 1987 A randomized trial of postoperative radiotherapy versus observation in stage II and III renal adenocarcinoma. A study by the Copenhagen Renal Cancer Study Group Scand J Urol Nephrol 21 285 289
    • (1987) Scand J Urol Nephrol , vol.21 , pp. 285-289
    • Kjaer, M.1    Iversen, P.2    Hvidt, V.3
  • 27
    • 27144550163 scopus 로고    scopus 로고
    • Extracranial stereotactic radiotherapy for primary and metastatic renal cell carcinoma
    • PJ Wersall H Blomgren I Lax 2005 Extracranial stereotactic radiotherapy for primary and metastatic renal cell carcinoma Radiother Oncol 77 88 95
    • (2005) Radiother Oncol , vol.77 , pp. 88-95
    • Wersall, P.J.1    Blomgren, H.2    Lax, I.3
  • 28
    • 34249934788 scopus 로고    scopus 로고
    • Radiotherapy to bone has utility in multifocal metastatic renal carcinoma
    • LM Reichel S Pohar J Heiner 2007 Radiotherapy to bone has utility in multifocal metastatic renal carcinoma Clin Orthop Relat Res 459 133 138
    • (2007) Clin Orthop Relat Res , vol.459 , pp. 133-138
    • Reichel, L.M.1    Pohar, S.2    Heiner, J.3
  • 29
    • 33750097999 scopus 로고    scopus 로고
    • Radiation therapy in the management of brain metastases from renal cell carcinoma
    • discussion 613, 616, 619-620 passsim
    • LS Doh RJ Amato AC Paulino 2006 Radiation therapy in the management of brain metastases from renal cell carcinoma Oncology (Williston Park) 20 603 613 discussion 613, 616, 619-620 passsim
    • (2006) Oncology (Williston Park) , vol.20 , pp. 603-613
    • Doh, L.S.1    Amato, R.J.2    Paulino, A.C.3
  • 30
    • 33748851898 scopus 로고    scopus 로고
    • A prospective phase II trial of using extracranial stereotactic radiotherapy in primary and metastatic renal cell carcinoma
    • C Svedman P Sandstrom P Pisa 2006 A prospective phase II trial of using extracranial stereotactic radiotherapy in primary and metastatic renal cell carcinoma Acta Oncol 45 870 875
    • (2006) Acta Oncol , vol.45 , pp. 870-875
    • Svedman, C.1    Sandstrom, P.2    Pisa, P.3
  • 31
    • 34247899028 scopus 로고    scopus 로고
    • Design of clinical trials of radiation combined with antiangiogenic therapy
    • S Senan EF Smit 2007 Design of clinical trials of radiation combined with antiangiogenic therapy Oncologist 12 465 477
    • (2007) Oncologist , vol.12 , pp. 465-477
    • Senan, S.1    Smit, E.F.2
  • 32
    • 0034038518 scopus 로고    scopus 로고
    • Chemotherapy for renal cell carcinoma
    • RJ Amato 2000 Chemotherapy for renal cell carcinoma Semin Oncol 27 177 186
    • (2000) Semin Oncol , vol.27 , pp. 177-186
    • Amato, R.J.1
  • 33
    • 0041411517 scopus 로고    scopus 로고
    • Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: A cytokine working group randomized trial
    • JI Clark MB Atkins WJ Urba 2003 Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: a cytokine working group randomized trial J Clin Oncol 21 3133 3140
    • (2003) J Clin Oncol , vol.21 , pp. 3133-3140
    • Clark, J.I.1    Atkins, M.B.2    Urba, W.J.3
  • 34
    • 0038514165 scopus 로고    scopus 로고
    • Phase III study of interferon alfa-NL as adjuvant treatment for resectable renal cell carcinoma: An Eastern Cooperative Oncology Group/Intergroup trial
    • EM Messing J Manola G Wilding 2003 Phase III study of interferon alfa-NL as adjuvant treatment for resectable renal cell carcinoma: an Eastern Cooperative Oncology Group/Intergroup trial J Clin Oncol 21 1214 1222
    • (2003) J Clin Oncol , vol.21 , pp. 1214-1222
    • Messing, E.M.1    Manola, J.2    Wilding, G.3
  • 36
    • 10744230275 scopus 로고    scopus 로고
    • Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial
    • D Jocham A Richter L Hoffmann 2004 Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial Lancet 363 594 599
    • (2004) Lancet , vol.363 , pp. 594-599
    • Jocham, D.1    Richter, A.2    Hoffmann, L.3
  • 37
    • 42149092508 scopus 로고    scopus 로고
    • Vaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: Clinical findings
    • E Jonasch C Wood P Tamboli 2008 Vaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: clinical findings Br J Cancer 98 1336 1341
    • (2008) Br J Cancer , vol.98 , pp. 1336-1341
    • Jonasch, E.1    Wood, C.2    Tamboli, P.3
  • 38
    • 46749085802 scopus 로고    scopus 로고
    • An adjuvant autologous therapeutic vaccine (HSPPC-96; Vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, open-label, randomised phase III trial
    • C Wood P Srivastava R Bukowski 2008 An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial Lancet 372 145 154
    • (2008) Lancet , vol.372 , pp. 145-154
    • Wood, C.1    Srivastava, P.2    Bukowski, R.3
  • 39
    • 34247333463 scopus 로고    scopus 로고
    • A review on follow-up strategies for renal cell carcinoma after nephrectomy
    • discussion 1501
    • A Skolarikos G Alivizatos P Laguna 2007 A review on follow-up strategies for renal cell carcinoma after nephrectomy Eur Urol 51 1490 1500 discussion 1501
    • (2007) Eur Urol , vol.51 , pp. 1490-1500
    • Skolarikos, A.1    Alivizatos, G.2    Laguna, P.3
  • 40
    • 0020376310 scopus 로고
    • Prognostic significance of morphologic parameters in renal cell carcinoma
    • SA Fuhrman LC Lasky C Limas 1982 Prognostic significance of morphologic parameters in renal cell carcinoma Am J Surg Pathol 6 655 663
    • (1982) Am J Surg Pathol , vol.6 , pp. 655-663
    • Fuhrman, S.A.1    Lasky, L.C.2    Limas, C.3
  • 41
    • 34547626961 scopus 로고    scopus 로고
    • Prognostic impact of carbonic anhydrase IX expression in human renal cell carcinoma
    • J Sandlund E Oosterwijk K Grankvist 2007 Prognostic impact of carbonic anhydrase IX expression in human renal cell carcinoma BJU Int 100 556 560
    • (2007) BJU Int , vol.100 , pp. 556-560
    • Sandlund, J.1    Oosterwijk, E.2    Grankvist, K.3
  • 42
    • 0034899264 scopus 로고    scopus 로고
    • Prognostic assessment of nonmetastatic renal cell carcinoma: A clinically based model
    • O Yaycioglu WW Roberts T Chan 2001 Prognostic assessment of nonmetastatic renal cell carcinoma: a clinically based model Urology 58 141 145
    • (2001) Urology , vol.58 , pp. 141-145
    • Yaycioglu, O.1    Roberts, W.W.2    Chan, T.3
  • 43
    • 0034966994 scopus 로고    scopus 로고
    • A postoperative prognostic nomogram for renal cell carcinoma
    • MW Kattan V Reuter RJ Motzer 2001 A postoperative prognostic nomogram for renal cell carcinoma J Urol 166 63 67
    • (2001) J Urol , vol.166 , pp. 63-67
    • Kattan, M.W.1    Reuter, V.2    Motzer, R.J.3
  • 44
    • 0036893892 scopus 로고    scopus 로고
    • An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score
    • I Frank ML Blute JC Cheville 2002 An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: the SSIGN score J Urol 168 2395 2400
    • (2002) J Urol , vol.168 , pp. 2395-2400
    • Frank, I.1    Blute, M.L.2    Cheville, J.C.3
  • 45
    • 0035868654 scopus 로고    scopus 로고
    • Improved prognostication of renal cell carcinoma using an integrated staging system
    • A Zisman AJ Pantuck F Dorey 2001 Improved prognostication of renal cell carcinoma using an integrated staging system J Clin Oncol 19 1649 1657
    • (2001) J Clin Oncol , vol.19 , pp. 1649-1657
    • Zisman, A.1    Pantuck, A.J.2    Dorey, F.3
  • 46
    • 4344578504 scopus 로고    scopus 로고
    • Use of the University of California Los Angeles integrated staging system to predict survival in renal cell carcinoma: An international multicenter study
    • JJ Patard HL Kim JS Lam 2004 Use of the University of California Los Angeles integrated staging system to predict survival in renal cell carcinoma: an international multicenter study J Clin Oncol 22 3316 3322
    • (2004) J Clin Oncol , vol.22 , pp. 3316-3322
    • Patard, J.J.1    Kim, H.L.2    Lam, J.S.3
  • 47
    • 0346749692 scopus 로고    scopus 로고
    • A preoperative clinical prognostic model for non-metastatic renal cell carcinoma
    • L Cindolo A de la Taille G Messina 2003 A preoperative clinical prognostic model for non-metastatic renal cell carcinoma BJU Int 92 901 905
    • (2003) BJU Int , vol.92 , pp. 901-905
    • Cindolo, L.1    De La Taille, A.2    Messina, G.3
  • 48
    • 25144474877 scopus 로고    scopus 로고
    • Comparison of predictive accuracy of four prognostic models for nonmetastatic renal cell carcinoma after nephrectomy: A multicenter European study
    • L Cindolo JJ Patard P Chiodini 2005 Comparison of predictive accuracy of four prognostic models for nonmetastatic renal cell carcinoma after nephrectomy: a multicenter European study Cancer 104 1362 1371
    • (2005) Cancer , vol.104 , pp. 1362-1371
    • Cindolo, L.1    Patard, J.J.2    Chiodini, P.3
  • 49
    • 0033514050 scopus 로고    scopus 로고
    • Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators
    • for the MRC Renal Cancer Collaborators
    • A Ritchie G Griffiths M Parmar for the MRC Renal Cancer Collaborators 1999 Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators Lancet 353 14 17
    • (1999) Lancet , vol.353 , pp. 14-17
    • Ritchie, A.1    Griffiths, G.2    Parmar, M.3
  • 50
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • G Fyfe RI Fisher SA Rosenberg 1995 Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy J Clin Oncol 13 688 696
    • (1995) J Clin Oncol , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3
  • 51
    • 16644401873 scopus 로고    scopus 로고
    • Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
    • DF McDermott MM Regan JI Clark 2005 Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma J Clin Oncol 23 133 141
    • (2005) J Clin Oncol , vol.23 , pp. 133-141
    • McDermott, D.F.1    Regan, M.M.2    Clark, J.I.3
  • 52
    • 0042914703 scopus 로고    scopus 로고
    • Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    • JC Yang RM Sherry SM Steinberg 2003 Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer J Clin Oncol 21 3127 3132
    • (2003) J Clin Oncol , vol.21 , pp. 3127-3132
    • Yang, J.C.1    Sherry, R.M.2    Steinberg, S.M.3
  • 53
    • 0024514149 scopus 로고
    • Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: Analysis of toxicity and management guidelines
    • KA Margolin AA Rayner MJ Hawkins 1989 Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines J Clin Oncol 7 486 498
    • (1989) J Clin Oncol , vol.7 , pp. 486-498
    • Margolin, K.A.1    Rayner, A.A.2    Hawkins, M.J.3
  • 54
    • 36448930484 scopus 로고    scopus 로고
    • Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: Results of a randomized controlled trial
    • S Negrier D Perol A Ravaud 2007 Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: results of a randomized controlled trial Cancer 110 2468 2477
    • (2007) Cancer , vol.110 , pp. 2468-2477
    • Negrier, S.1    Perol, D.2    Ravaud, A.3
  • 55
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • RJ Motzer J Bacik BA Murphy 2002 Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma J Clin Oncol 20 289 296
    • (2002) J Clin Oncol , vol.20 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3
  • 56
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • RJ Motzer M Mazumdar J Bacik 1999 Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma J Clin Oncol 17 2530 2540
    • (1999) J Clin Oncol , vol.17 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3
  • 57
    • 4644268358 scopus 로고    scopus 로고
    • Prognostic factors in patients with advanced renal cell carcinoma: Development of an international kidney cancer working group
    • RM Bukowski S Negrier P Elson 2004 Prognostic factors in patients with advanced renal cell carcinoma: development of an international kidney cancer working group Clin Cancer Res 10 6310S 6314S
    • (2004) Clin Cancer Res , vol.10
    • Bukowski, R.M.1    Negrier, S.2    Elson, P.3
  • 58
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • DB Mendel AD Laird X Xin 2003 In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship Clin Cancer Res 9 327 337
    • (2003) Clin Cancer Res , vol.9 , pp. 327-337
    • Mendel, D.B.1    Laird, A.D.2    Xin, X.3
  • 59
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • RJ Motzer MD Michaelson BG Redman 2006 Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma J Clin Oncol 24 16 24
    • (2006) J Clin Oncol , vol.24 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 60
    • 33744954585 scopus 로고    scopus 로고
    • Sunitinib in patients with metastatic renal cell carcinoma
    • RJ Motzer BI Rini RM Bukowski 2006 Sunitinib in patients with metastatic renal cell carcinoma JAMA 295 2516 2524
    • (2006) JAMA , vol.295 , pp. 2516-2524
    • Motzer, R.J.1    Rini, B.I.2    Bukowski, R.M.3
  • 61
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • RJ Motzer TE Hutson P Tomczak 2007 Sunitinib versus interferon alfa in metastatic renal-cell carcinoma N Engl J Med 356 115 124
    • (2007) N Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 63
    • 0036983115 scopus 로고    scopus 로고
    • The Ras-Raf-MEK-ERK pathway in the treatment of cancer
    • RA Hilger ME Scheulen D Strumberg 2002 The Ras-Raf-MEK-ERK pathway in the treatment of cancer Onkologie 25 511 518
    • (2002) Onkologie , vol.25 , pp. 511-518
    • Hilger, R.A.1    Scheulen, M.E.2    Strumberg, D.3
  • 64
    • 36249017922 scopus 로고    scopus 로고
    • Phase II study to investigate the efficacy, safety, and pharmacokinetics of sorafenib in Japanese patients with advanced renal cell carcinoma
    • H Akaza T Tsukamoto M Murai 2007 Phase II study to investigate the efficacy, safety, and pharmacokinetics of sorafenib in Japanese patients with advanced renal cell carcinoma Jpn J Clin Oncol 37 755 762
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 755-762
    • Akaza, H.1    Tsukamoto, T.2    Murai, M.3
  • 65
    • 34948863852 scopus 로고    scopus 로고
    • 2007 ASCO annual meeting proceedings, part i
    • Final results of the randomized phase III trial of sorafenib in advanced renal cell carcinoma: survival and biomarker analysis (June 20 supplement), abstr 5023
    • Bukowski RM, Eisen T, Szczylik C, Stadler WM, Simantov R, Shan M, Elting J, Pena C, Escudier B (2007) Final results of the randomized phase III trial of sorafenib in advanced renal cell carcinoma: survival and biomarker analysis. In: 2007 ASCO annual meeting proceedings, part I. J Clin Oncol, vol 25, no. 18S (June 20 supplement), abstr 5023
    • (2007) J Clin Oncol , vol.25 , Issue.18
    • Bukowski, R.M.1    Eisen, T.2    Szczylik, C.3    Stadler, W.M.4    Simantov, R.5    Shan, M.6    Elting, J.7    Pena, C.8    Escudier, B.9
  • 66
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • B Escudier T Eisen WM Stadler 2007 Sorafenib in advanced clear-cell renal-cell carcinoma N Engl J Med 356 125 134
    • (2007) N Engl J Med , vol.356 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 67
    • 62549107594 scopus 로고    scopus 로고
    • 2007 ASCO annual meeting proceedings, part i
    • Randomized phase II trial of first-line treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: final results (June 20 supplement), abstr 5025
    • Szczylik C, Demkow T, Staehler M, Rolland F, Negrier S, Hutson TE, Bukowski RM, Scheuring UJ, Burk K, Escudier B (2007) Randomized phase II trial of first-line treatment with sorafenib versus interferon in patients with advanced renal cell carcinoma: final results. In: 2007 ASCO annual meeting proceedings, part I. J Clin Oncol, vol 25, no. 18S (June 20 supplement), abstr 5025
    • (2007) J Clin Oncol , vol.25 , Issue.18
    • Szczylik, C.1    Demkow, T.2    Staehler, M.3    Rolland, F.4    Negrier, S.5    Hutson, T.E.6    Bukowski, R.M.7    Scheuring, U.J.8    Burk, K.9    Escudier, B.10
  • 68
    • 14644415949 scopus 로고    scopus 로고
    • Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma
    • BI Rini EJ Small 2005 Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma J Clin Oncol 23 1028 1043
    • (2005) J Clin Oncol , vol.23 , pp. 1028-1043
    • Rini, B.I.1    Small, E.J.2
  • 69
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • LG Presta H Chen SJ O'Connor 1997 Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders Cancer Res 57 4593 4599
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3
  • 70
    • 35648938219 scopus 로고    scopus 로고
    • Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
    • RM Bukowski FF Kabbinavar RA Figlin 2007 Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer J Clin Oncol 25 4536 4541
    • (2007) J Clin Oncol , vol.25 , pp. 4536-4541
    • Bukowski, R.M.1    Kabbinavar, F.F.2    Figlin, R.A.3
  • 71
    • 37349080670 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
    • B Escudier A Pluzanska P Koralewski 2007 Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial Lancet 370 2103 2111
    • (2007) Lancet , vol.370 , pp. 2103-2111
    • Escudier, B.1    Pluzanska, A.2    Koralewski, P.3
  • 73
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • JC Yang L Haworth RM Sherry 2003 A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer N Engl J Med 349 427 434
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 74
    • 48749092867 scopus 로고    scopus 로고
    • First-line bevacizumab combined with reduced dose interferon-alpha2a is active in patients with metastatic renal cell carcinoma
    • B Melichar P Koralewski A Ravaud 2008 First-line bevacizumab combined with reduced dose interferon-alpha2a is active in patients with metastatic renal cell carcinoma Ann Oncol 19 1470 1476
    • (2008) Ann Oncol , vol.19 , pp. 1470-1476
    • Melichar, B.1    Koralewski, P.2    Ravaud, A.3
  • 75
    • 0036789574 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
    • CC Hudson M Liu GG Chiang 2002 Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin Mol Cell Biol 22 7004 7014
    • (2002) Mol Cell Biol , vol.22 , pp. 7004-7014
    • Hudson, C.C.1    Liu, M.2    Chiang, G.G.3
  • 76
    • 33745242315 scopus 로고    scopus 로고
    • Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus
    • D Del Bufalo L Ciuffreda D Trisciuoglio 2006 Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus Cancer Res 66 5549 5554
    • (2006) Cancer Res , vol.66 , pp. 5549-5554
    • Del Bufalo, D.1    Ciuffreda, L.2    Trisciuoglio, D.3
  • 77
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • MB Atkins M Hidalgo WM Stadler 2004 Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma J Clin Oncol 22 909 918
    • (2004) J Clin Oncol , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3
  • 78
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • G Hudes M Carducci P Tomczak 2007 Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma N Engl J Med 356 2271 2281
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 79
    • 62549099668 scopus 로고    scopus 로고
    • A phase II study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic renal cell carcinoma which has progressed on tyrosine kinase inhibition therapy
    • May 20 suppl
    • J Jac RJ Amato S Giessinger S Saxena JP Willis 2008 A phase II study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic renal cell carcinoma which has progressed on tyrosine kinase inhibition therapy J Clin Oncol 26 May 20 suppl abstr 5113
    • (2008) J Clin Oncol , vol.26 , pp. 5113
    • Jac, J.1    Amato, R.J.2    Giessinger, S.3    Saxena, S.4    Willis, J.P.5
  • 80
    • 55249103589 scopus 로고    scopus 로고
    • RAD001 vs placebo in patients with metastatic renal cell carcinoma (RCC) after progression on VEGFr-TKI therapy: Results from a randomized, double-blind, multicenter phase-III study
    • May 20 suppl
    • RJ Motzer B Escudier S Oudard C Porta TE Hutson S Bracarda N Hollaender G Urbanowitz A Kay A Ravaud 2008 RAD001 vs placebo in patients with metastatic renal cell carcinoma (RCC) after progression on VEGFr-TKI therapy: results from a randomized, double-blind, multicenter phase-III study J Clin Oncol 26 May 20 suppl abstr LBA5026
    • (2008) J Clin Oncol , vol.26 , pp. 5026
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3    Porta, C.4    Hutson, T.E.5    Bracarda, S.6    Hollaender, N.7    Urbanowitz, G.8    Kay, A.9    Ravaud, A.10
  • 81
    • 1442290393 scopus 로고    scopus 로고
    • Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma
    • RJ Motzer J Bacik LH Schwartz 2004 Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma J Clin Oncol 22 454 463
    • (2004) J Clin Oncol , vol.22 , pp. 454-463
    • Motzer, R.J.1    Bacik, J.2    Schwartz, L.H.3


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