Investigation into the sorption of nitroglycerin and diazepam into PVC tubes and alternative tube materials during application

International Journal of Pharmaceutics

Volumn 369, Issue 1-2, 2009, Pages 30-37

  Treleano, Anna ^a   Wolz, Gerd ^a   Brandsch, Rainer ^b   Welle, Frank ^a  

^a FRAUNHOFER INSTITUTE FOR PROCESS ENGINEERING AND PACKAGING IVV   (Germany)

^b MDCTec Ltd   (Germany)

Author keywords

Diazepam; Diffusion; Infusion administration set; Mathematical modelling; Nitroglycerin; PVC tubing; Sorption

Indexed keywords

DI (2 ETHYLHEXYL)ADIPATE; DI (2 ETHYLHEXYL)TEREPHTHALATE; DI (ISONONYL)CYCLOHEXAN 1,2 DICARBOXYLATE; DIAZEPAM; DIAZEPAM RATIOPHARM; ETHYLENE VINYL ACETATE COPOLYMER; GLYCERYL TRINITRATE; PLASTICIZER; POLYETHYLENE; POLYMER; POLYPROPYLENE; POLYURETHAN; POLYVINYLCHLORIDE; SILICONE; TRIMELLITIC ACID TRIS(2 ETHYLHEXYL) ESTER; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG DIFFUSION; DRUG SOLUTION; DRUG SORPTION; DRUG TRANSPORT; HARDNESS; LEACHING; MATERIAL STATE; MATERIALS TESTING; MATHEMATICAL ANALYSIS; PARAMETER; PRIORITY JOURNAL; SIMULATION; TUBE;

ADSORPTION; DIAZEPAM; DIETHYLHEXYL PHTHALATE; DRUG PACKAGING; DRUG STABILITY; DRUG STORAGE; INFUSIONS, INTRAVENOUS; MODELS, THEORETICAL; NITROGLYCERIN; PLASTICIZERS; POLYMERS; POLYVINYL CHLORIDE;

EID: 61349133455     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.10.024     Document Type: Article

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