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60949101245
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While we consider that the decomposition is due to oxidation of 2, the reason why 2 survives the oxidative reaction conditions is unclear
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While we consider that the decomposition is due to oxidation of 2, the reason why 2 survives the oxidative reaction conditions is unclear.
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60949101769
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The low methylation yield is due to the electron-withdrawing ester functionality, which lowers the nucleophilicity of the penta-adduct anion
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The low methylation yield is due to the electron-withdrawing ester functionality, which lowers the nucleophilicity of the penta-adduct anion.
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20
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In the 20% DMSO/chlorobenzene solvent system, formation of a small amount of penta-adduct 2 was observed even under deoxygenated conditions
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In the 20% DMSO/chlorobenzene solvent system, formation of a small amount of penta-adduct 2 was observed even under deoxygenated conditions.
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25
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60949094166
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Isolation of dimerized tetra-adduct 8 was difficult since the product was unstable to air-oxidation and also the dimer comprises a complex mixture of isomers.
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Isolation of dimerized tetra-adduct 8 was difficult since the product was unstable to air-oxidation and also the dimer comprises a complex mixture of isomers.
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Some overreacted byproducts were observed in the syntheses of monoadducts due to the presence of DMSO, which presumably acts as an oxidant
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Some overreacted byproducts were observed in the syntheses of monoadducts due to the presence of DMSO, which presumably acts as an oxidant.
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