-
1
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
-
Adachi O., Kawai T., Takeda K., Matsumoto M., Tsutsui H., Sakagami M., Nakanishi K., and Akira S. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9 (1998) 143-150
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
2
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
3
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou L., Holt A.C., Medzhitov R., and Flavell R.A. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413 (2001) 732-738
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
4
-
-
0031057644
-
Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm
-
Arenzana-Seisdedos F., Turpin P., Rodriguez M., Thomas D., Hay R.T., Virelizier J.L., and Dargemont C. Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm. J. Cell Sci. 110 Pt 3 (1997) 369-378
-
(1997)
J. Cell Sci.
, vol.110
, Issue.PART 3
, pp. 369-378
-
-
Arenzana-Seisdedos, F.1
Turpin, P.2
Rodriguez, M.3
Thomas, D.4
Hay, R.T.5
Virelizier, J.L.6
Dargemont, C.7
-
5
-
-
5944221106
-
Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCRI
-
Barlic J., Andrews J.D., Kelvin A.A., Bosinger S.E., DeVries M.E., Xu L., Dobransky T., Feldman R.D., Ferguson S.S., and Kelvin D.J. Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCRI. Nat. Immunol. 1 (2000) 227-233
-
(2000)
Nat. Immunol.
, vol.1
, pp. 227-233
-
-
Barlic, J.1
Andrews, J.D.2
Kelvin, A.A.3
Bosinger, S.E.4
DeVries, M.E.5
Xu, L.6
Dobransky, T.7
Feldman, R.D.8
Ferguson, S.S.9
Kelvin, D.J.10
-
6
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer S., Kirschning C.J., Hacker H., Redecke V., Hausmann S., Akira S., Wagner H., and Lipford G.B. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 9237-9242
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 9237-9242
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
Wagner, H.7
Lipford, G.B.8
-
7
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan C. Nitric oxide and the immune response. Nat. Immunol. 2 (2001) 907-916
-
(2001)
Nat. Immunol.
, vol.2
, pp. 907-916
-
-
Bogdan, C.1
-
8
-
-
0032488907
-
2-adrenergic receptor mRNA stability occurs via a specific AU-rich element
-
2-adrenergic receptor mRNA stability occurs via a specific AU-rich element. J. Biol. Chem. 273 (1998) 3223-3229
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3223-3229
-
-
Danner, S.1
Frank, M.2
Lohse, M.J.3
-
9
-
-
0023706894
-
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
-
Ding A.H., Nathan C.F., and Stuehr D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141 (1988) 2407-2412
-
(1988)
J. Immunol.
, vol.141
, pp. 2407-2412
-
-
Ding, A.H.1
Nathan, C.F.2
Stuehr, D.J.3
-
10
-
-
0034079611
-
Neural immunoregulation: emerging roles for nerves in immune homeostasis and disease
-
Downing J.E., and Miyan J.A. Neural immunoregulation: emerging roles for nerves in immune homeostasis and disease. Immunol. Today 21 (2000) 281-289
-
(2000)
Immunol. Today
, vol.21
, pp. 281-289
-
-
Downing, J.E.1
Miyan, J.A.2
-
11
-
-
0033638849
-
The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system
-
Elenkov I.J., Wilder R.L., Chrousos G.P., and Vizi E.S. The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system. Pharmacol. Rev. 52 (2000) 595-638
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 595-638
-
-
Elenkov, I.J.1
Wilder, R.L.2
Chrousos, G.P.3
Vizi, E.S.4
-
12
-
-
0037188469
-
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
-
Fong A.M., Premont R.T., Richardson R.M., Yu Y.R., Lefkowitz R.J., and Patel D.D. Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 7478-7483
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 7478-7483
-
-
Fong, A.M.1
Premont, R.T.2
Richardson, R.M.3
Yu, Y.R.4
Lefkowitz, R.J.5
Patel, D.D.6
-
13
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways
-
Gao H., Sun Y., Wu Y., Luan B., Wang Y., Qu B., and Pei G. Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways. Mol. Cell 14 (2004) 303-317
-
(2004)
Mol. Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
Pei, G.7
-
14
-
-
0037119385
-
Norepinephrine increases IκBα expression in astrocytes
-
Gavrilyuk V., Dello Russo C., Heneka M.T., Pelligrino D., Weinberg G., and Feinstein D.L. Norepinephrine increases IκBα expression in astrocytes. J. Biol. Chem. 277 (2002) 29662-29668
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29662-29668
-
-
Gavrilyuk, V.1
Dello Russo, C.2
Heneka, M.T.3
Pelligrino, D.4
Weinberg, G.5
Feinstein, D.L.6
-
15
-
-
0032536875
-
Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock
-
Hierholzer C., Harbrecht B., Menezes J.M., Kane J., MacMicking J., Nathan C.F., Peitzman A.B., Billiar T.R., and Tweardy D.J. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J. Exp. Med. 187 (1998) 917-928
-
(1998)
J. Exp. Med.
, vol.187
, pp. 917-928
-
-
Hierholzer, C.1
Harbrecht, B.2
Menezes, J.M.3
Kane, J.4
MacMicking, J.5
Nathan, C.F.6
Peitzman, A.B.7
Billiar, T.R.8
Tweardy, D.J.9
-
16
-
-
0034960907
-
Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα
-
Huang T.T., and Miyamoto S. Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα. Mol. Cell Biol. 21 (2001) 4737-4747
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 4737-4747
-
-
Huang, T.T.1
Miyamoto, S.2
-
17
-
-
4444294395
-
2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation
-
2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation. Biochem. Biophys. Res. Commun. 322 (2004) 979-984
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 979-984
-
-
Itoh, C.E.1
Kizaki, T.2
Hitomi, Y.3
Hanawa, T.4
Kamiya, S.5
Ookawara, T.6
Suzuki, K.7
Izawa, T.8
Saitoh, D.9
Haga, S.10
Ohno, H.11
-
19
-
-
0035339861
-
Endotoxin-induced maturation of MyD88-deficient dendritic cells
-
Kaisho T., Takeuchi O., Kawai T., Hoshino K., and Akira S. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166 (2001) 5688-5694
-
(2001)
J. Immunol.
, vol.166
, pp. 5688-5694
-
-
Kaisho, T.1
Takeuchi, O.2
Kawai, T.3
Hoshino, K.4
Akira, S.5
-
20
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T., Adachi O., Ogawa T., Takeda K., and Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11 (1999) 115-122
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
21
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T., Takeuchi O., Fujita T., Inoue J., Muhlradt P.F., Sato S., Hoshino K., and Akira S. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 167 (2001) 5887-5894
-
(2001)
J. Immunol.
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
22
-
-
44849134837
-
2-adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-κB activation through β-arrestin 2
-
2-adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-κB activation through β-arrestin 2. Immunology 124 (2008) 348-356
-
(2008)
Immunology
, vol.124
, pp. 348-356
-
-
Kizaki, T.1
Izawa, T.2
Sakurai, T.3
Haga, S.4
Taniguchi, N.5
Tajiri, H.6
Watanabe, K.7
Day, N.K.8
Toba, K.9
Ohno, H.10
-
23
-
-
0033844288
-
high activated macrophages
-
high activated macrophages. J. Leukoc. Biol. 68 (2000) 21-30
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 21-30
-
-
Kizaki, T.1
Ookawara, T.2
Iwabuchi, K.3
Onoé, K.4
Day, N.K.5
Good, R.A.6
Maruyama, N.7
Haga, S.8
Matsuura, N.9
Ohira, Y.10
Ohno, H.11
-
24
-
-
0035930918
-
Negative regulation of LPS-stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1
-
Kizaki T., Suzuki K., Hitomi Y., Iwabuchi K., Onoé K., Haga S., Ishida H., Ookawara T., Suzuki K., and Ohno H. Negative regulation of LPS-stimulated expression of inducible nitric oxide synthase by AP-1 in macrophage cell line J774A.1. Biochem. Biophys. Res. Commun. 289 (2001) 1031-1038
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.289
, pp. 1031-1038
-
-
Kizaki, T.1
Suzuki, K.2
Hitomi, Y.3
Iwabuchi, K.4
Onoé, K.5
Haga, S.6
Ishida, H.7
Ookawara, T.8
Suzuki, K.9
Ohno, H.10
-
25
-
-
0037047142
-
Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages
-
Kizaki T., Suzuki K., Hitomi Y., Taniguchi N., Saitoh D., Watanabe K., Onoé K., Day N.K., Good R.A., and Ohno H. Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 9392-9397
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9392-9397
-
-
Kizaki, T.1
Suzuki, K.2
Hitomi, Y.3
Taniguchi, N.4
Saitoh, D.5
Watanabe, K.6
Onoé, K.7
Day, N.K.8
Good, R.A.9
Ohno, H.10
-
26
-
-
44649198335
-
Adaptation of macrophages to exercise training improves innate immunity
-
Kizaki T., Takemasa T., Sakurai T., Izawa T., Hanawa T., Kamiya S., Haga S., Imaizumi K., and Ohno H. Adaptation of macrophages to exercise training improves innate immunity. Biochem. Biophys. Res. Commun. 372 (2008) 152-156
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.372
, pp. 152-156
-
-
Kizaki, T.1
Takemasa, T.2
Sakurai, T.3
Izawa, T.4
Hanawa, T.5
Kamiya, S.6
Haga, S.7
Imaizumi, K.8
Ohno, H.9
-
27
-
-
0035210457
-
+ T and B lymphocyte function in vitro and in vivo
-
+ T and B lymphocyte function in vitro and in vivo. Pharmacol. Rev. 53 (2001) 487-525
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 487-525
-
-
Kohm, A.P.1
Sanders, V.M.2
-
28
-
-
0033601915
-
Expression of IκBα in the nucleus of human peripheral blood T lymphocytes
-
Lain de Lera T., Folgueira L., Martin A.G., Dargemont C., Pedraza M.A., Bermejo M., Bonay P., Fresno M., and Alcami J. Expression of IκBα in the nucleus of human peripheral blood T lymphocytes. Oncogene 18 (1999) 1581-1588
-
(1999)
Oncogene
, vol.18
, pp. 1581-1588
-
-
Lain de Lera, T.1
Folgueira, L.2
Martin, A.G.3
Dargemont, C.4
Pedraza, M.A.5
Bermejo, M.6
Bonay, P.7
Fresno, M.8
Alcami, J.9
-
29
-
-
0036473397
-
The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
-
Luttrell L.M., and Lefkowitz R.J. The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals. J. Cell Sci. 115 (2002) 455-465
-
(2002)
J. Cell Sci.
, vol.115
, pp. 455-465
-
-
Luttrell, L.M.1
Lefkowitz, R.J.2
-
30
-
-
0037414637
-
p105.IκBγ and prototypical IκBs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-κB
-
Moorthy A.K., and Ghosh G. p105.IκBγ and prototypical IκBs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-κB. J. Biol. Chem. 278 (2003) 556-566
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 556-566
-
-
Moorthy, A.K.1
Ghosh, G.2
-
31
-
-
0028145741
-
2 adrenergic receptor mRNA inhibits receptor synthesis
-
2 adrenergic receptor mRNA inhibits receptor synthesis. J. Biol. Chem. 269 (1994) 4497-4505
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4497-4505
-
-
Parola, A.L.1
Kobilka, B.K.2
-
32
-
-
0031303091
-
Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-κB-mediated transcription
-
Parry G.C., and Mackman N. Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-κB-mediated transcription. J. Immunol. 159 (1997) 5450-5456
-
(1997)
J. Immunol.
, vol.159
, pp. 5450-5456
-
-
Parry, G.C.1
Mackman, N.2
-
33
-
-
0036499130
-
Arresting developments in heptahelical receptor signaling and regulation
-
Perry S.J., and Lefkowitz R.J. Arresting developments in heptahelical receptor signaling and regulation. Trends Cell Biol. 12 (2002) 130-138
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 130-138
-
-
Perry, S.J.1
Lefkowitz, R.J.2
-
34
-
-
0034680440
-
IκBα and IκBα/NF-κB complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2
-
Prigent M., Barlat I., Langen H., and Dargemont C. IκBα and IκBα/NF-κB complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2. J. Biol. Chem. 275 (2000) 36441-36449
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36441-36449
-
-
Prigent, M.1
Barlat, I.2
Langen, H.3
Dargemont, C.4
-
35
-
-
0033605424
-
Nuclear retention of IκBα protects it from signal-induced degradation and inhibits nuclear factor κB transcriptional activation
-
Rodriguez M.S., Thompson J., Hay R.T., and Dargemont C. Nuclear retention of IκBα protects it from signal-induced degradation and inhibits nuclear factor κB transcriptional activation. J. Biol. Chem. 274 (1999) 9108-9115
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9108-9115
-
-
Rodriguez, M.S.1
Thompson, J.2
Hay, R.T.3
Dargemont, C.4
-
36
-
-
0037147145
-
β-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
-
Sun Y., Cheng Z., Ma L., and Pei G. β-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J. Biol. Chem. 277 (2002) 49212-49219
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49212-49219
-
-
Sun, Y.1
Cheng, Z.2
Ma, L.3
Pei, G.4
-
38
-
-
26944443968
-
Distinct roles of IκB proteins in regulating constitutive NF-κB activity
-
Tergaonkar V., Correa R.G., Ikawa M., and Verma I.M. Distinct roles of IκB proteins in regulating constitutive NF-κB activity. Nat. Cell Biol. 7 (2005) 921-923
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 921-923
-
-
Tergaonkar, V.1
Correa, R.G.2
Ikawa, M.3
Verma, I.M.4
-
39
-
-
0033598811
-
2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species
-
2-adrenergic receptor mRNA by mutagenesis and identification of the homologous AU-rich region from different species. Biochemistry 38 (1999) 15564-15572
-
(1999)
Biochemistry
, vol.38
, pp. 15564-15572
-
-
Tholanikunnel, B.G.1
Raymond, J.R.2
Malbon, C.C.3
-
40
-
-
0141608603
-
β-arrestin-2 regulates the development of allergic asthma
-
Walker J.K., Fong A.M., Lawson B.L., Savov J.D., Patel D.D., Schwartz D.A., and Lefkowitz R.J. β-arrestin-2 regulates the development of allergic asthma. J. Clin. Invest. 112 (2003) 566-574
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 566-574
-
-
Walker, J.K.1
Fong, A.M.2
Lawson, B.L.3
Savov, J.D.4
Patel, D.D.5
Schwartz, D.A.6
Lefkowitz, R.J.7
-
42
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., Takeuchi O., Sugiyama M., Okabe M., Takeda K., and Akira S. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301 (2003) 640-643
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
|