Possible contribution of rubiadin, a metabolite of madder color, to renal carcinogenesis in rats

Food and Chemical Toxicology

Volumn 47, Issue 4, 2009, Pages 752-759

  Inoue, Kaoru ^a   Yoshida, Midori ^a   Takahashi, Miwa ^a   Fujimoto, Hitoshi ^a   Ohnishi, Kuniyoshi ^b   Nakashima, Koichi ^b   Shibutani, Makoto ^a,c   Hirose, Masao ^a,d   Nishikawa, Akiyoshi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b SAN EI GEN F F I INC   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^d Food Safety Commission of Japan   (Japan)

Author keywords

Alizarin; F344 rats; Kidney; Lucidin; Lucidin 3 O primeveroside; Rubiadin

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALIZARIN; CARCINOGEN; FOOD ADDITIVE; FOOD DYE; RUBIADIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOPHIL; CARCINOGENESIS; CARCINOGENICITY; CELL DEGENERATION; CELL ENLARGEMENT; CELL LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; FISCHER 344 RAT; GENOTOXICITY; KIDNEY; KIDNEY CANCER; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; MALE; METABOLITE; NONHUMAN; OXIDATIVE STRESS; PRECANCER; RAT; SWELLING;

ANIMALS; ANTHRAQUINONES; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; KIDNEY NEOPLASMS; MALE; ORGAN SIZE; PLANT EXTRACTS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED F344; RUBIA;

RATTUS; RUBIA TINCTORUM;

EID: 60849134254     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.01.003     Document Type: Article

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