Loss of the cholesterol-binding protein Prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

Journal of Neuroscience

Volumn 29, Issue 7, 2009, Pages 2297-2308

  Zacchigna, Serena ^a,b   Oh, Hideyasu ^a,b   Wilsch Bräuninger, Michaela ^c   Missol Kolka, Ewa ^c,d   Jászai, József ^d   Jansen, Sandra ^a,b   Tanimoto, Naoyuki ^e   Tonagel, Felix ^e   Seeliger, Mathias ^e   Huttner, Wieland B ^e   Corbeil, Denis ^c   Dewerchin, Mieke ^c,d   Vinckier, Stefan ^a,b   Moons, Lieve ^a,b   Carmeliet, Peter ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^e UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Apoptosis; Blindness; Degeneration; Eye; Knockout; Retina

Indexed keywords

CD133 ANTIGEN; CHOLESTEROL; MEMBRANE ANTIGEN; PROMININ 1; UNCLASSIFIED DRUG; VISUAL PIGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DEGENERATION; EMBRYO; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MORPHOGENESIS; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; PRIORITY JOURNAL; RETINA BLOOD VESSEL; RETINA DEVELOPMENT; STEM CELL; VERTEBRATE; VISUAL IMPAIRMENT;

ANIMALS; ANTIGENS, CD; CHOLESTEROL; DOWN-REGULATION; ENDOTHELIAL CELLS; GENETIC PREDISPOSITION TO DISEASE; GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE DEGENERATION; PEPTIDES; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RETINAL ARTERY; RETINAL DEGENERATION; RETINAL PIGMENTS; STEM CELLS; VISION, OCULAR;

EID: 60849132741     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2034-08.2009     Document Type: Article

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