Preparation and osteoinduction capacity of collagen/bone morphogenetic protein composites

Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology

Volumn 24, Issue 2, 2008, Pages 272-277

  Tan, Weiqiang ^a   Xu, Jinghong ^a   Liu, Youshan ^a   Lin, Jun ^a   Wang, Huiming ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

BMP 2; Bone defect; Bone morphogenetic protein 2; Collagen; Ectopic bone formation

Indexed keywords

ORYCTOLAGUS CUNICULUS;

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1;

ANIMAL; ARTICLE; BONE REGENERATION; BONE TRANSPLANTATION; CHEMISTRY; DRUG EFFECT; FEMALE; IMPLANT; JAW DISEASE; MALE; METHODOLOGY; RABBIT; RANDOMIZATION; SKELETAL MUSCLE;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; BONE TRANSPLANTATION; COLLAGEN TYPE I; FEMALE; IMPLANTS, EXPERIMENTAL; MALE; MANDIBULAR INJURIES; MUSCLE, SKELETAL; RABBITS; RANDOM ALLOCATION;

EID: 60849127799     PISSN: 10003061     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Łukaszewicz E, Chrzanowska M, Jerysz A, Chemońska B. Attempts on freezing the Greylag (Anser anser L.) gander semen. Anim Reprod Sci, 2004, 80 (1-2): 163-173.
2. Bessho K, Carnes DL, Cavin R, Ong JL. Experimental studies on bone induction using low-molecular-weight poly (DL-lactide-co-glycolide) as a carrier for recombinant human bone morphogenetic protein-2. J Biomed Mater Res, 2002, 61 (1): 61-65.
3. Woo BH, Fink BF, Page R, Schrier JA, Jo YW, Jiang G, DeLuca M, Vasconez HC, DeLuca PP. Enhancement of bone growth by sustained delivery of recombinant human bone morphogenetic protein-2 in a polymeric matrix. Pharm Res, 2001, 18 (12): 1747-1753.
4. Yamamoto M, Takahashi Y, Tabata Y. Controlled release by biodegradable hydrogels enhances the ectopic bone formation of bone morphogenetic protein. Biomaterials, 2003, 24 (24): 4375-4383.
5. Maeda H, Sano A, Fujioka K. Profile of rhBMP-2 release from collagen minipellet and induction of ectopic bone formation. Drug Dev Ind Pharm, 2004, 30 (5): 473-480.
6. Yang XB, Whitaker MJ, Sebald W, Clarke N, Howdle SM, Shakesheff KM, Oreffo RO. Human osteoprogenitor bone formation using encapsulated bone morphogenetic protein 2 in porous polymer scaffolds. Tissue Eng, 2004, 10 (7-8): 1037-1045.
7. Dalkýz M, Ozcan A, Yapar M, Gökay N, Yüncü M. Evaluation of the effects of different biomaterials on bone defects. Implant Dent, 2000, 9 (3): 226-235.
8. Zhang X, Fan X, Gao X, Bai H, Li Y. Observation of collagen assembly process by using atomic force microscopy. Acta Polym Sin, 2006, (8): 959-963.
9. Barbani N, Cascone MG, Giusti P, Lazzeri L, Polacco G, Pizzirani G. Bioartificial materials based on collagen: 2. Mixtures of soluble collagen and poly (vinylalcohol) cross-linked with gaseous glutaraldehyde. J Biomater Sci Polym Ed, 1995, 7 (6): 471-484.
10. Fonseca MJ, Alsina MA, Reig F. Coating liposomes with collagen (Mr 50, 000) increases uptake into liver. Biochim Biophys Acta, 1996, 1279 (2): 259-265.
11. Shi X, Wu S, Sun C. A study on collagen association state in aqueous solution using fluorescence probe. Acta Polym Sin, 1998, (4): 406-411.
12. Nakagawa T, Tagawa T. Ultrastructural study of direct bone formation induced by BMPs-collagen complex implanted into an ectopic site. Oral Dis, 2000, 6 (3): 172-179.
13. Okubo Y, Bessho K, Fujimura K, Konishi Y, Kusumoto K, Ogawa Y, Iizuka T. Osteoinduction by recombinant human bone morphogenetic protein-2 at intramuscular, intermuscular, subcutaneous and intrafatty sites. Int J Oral Maxillofac Surg, 2000, 29 (1): 62-66.
14. Betz RR. Limitations of autograft and allograft: new synthetic solutions. Orthopedics, 2002, 25 (5 Suppl): s561-570.
15. Bauer TW, Muschler GF. Bone graft materials. An overview of the basic science. Clin Orthop, 2000, (371): 10-27.
16. Nakagawa T, Tagawa T. Ultrastructural study of direct bone formation induced by BMPs-collagen complex implanted into an ectopic site. Oral Dis, 2000, 6 (3): 172-179.
17. Vehof JW, Takita H, Kuboki Y, Spauwen PH, Jansen JA. Histological characterization of the early stages of bone morphogenetic protein-induced osteogenesis. J Biomed Mater Res, 2002, 61 (3): 440-449.