Histological characterization of the early stages of bone morphogenetic protein-induced osteogenesis

Journal of Biomedical Materials Research

Volumn 61, Issue 3, 2002, Pages 440-449

  Vehof, J W M ^a   Takita, H ^b   Kuboki, Y ^b   Spauwen, P H M ^a   Jansen, J A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Bone engineering; Bone morphogenetic protein; Ectopic; Osteogenesis; Scaffold

Indexed keywords

CARTILAGE; FIBROUS MEMBRANES; PROTEINS; TISSUE; TITANIUM;

OETEOGENESIS;

BONE;

BONE MORPHOGENETIC PROTEIN; CALCIUM PHOSPHATE; HYDROXYAPATITE; TITANIUM; ALPHA TRICALCIUM PHOSPHATE; ALPHA-TRICALCIUM PHOSPHATE; CALCIUM PHOSPHATE MONOBASIC; DICALCIUM PHOSPHATE ANHYDROUS; GLASS; TETRACALCIUM PHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE GROWTH; CARTILAGE; CATTLE; CONTROLLED STUDY; GROWTH STIMULATION; HISTOLOGY; IMPLANT; NONHUMAN; POROSITY; RAT; TISSUE ENGINEERING; ANIMAL; ANIMAL MODEL; BONE DEVELOPMENT; BONE PROSTHESIS; BONE REGENERATION; CELL DIFFERENTIATION; CELL DIVISION; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; IMPLANTATION; MATERIALS TESTING; MESODERM; METATARSAL BONE; STANDARD; WISTAR RAT;

ANIMALS; BONE MORPHOGENETIC PROTEINS; BONE SUBSTITUTES; CALCIUM PHOSPHATES; CARTILAGE; CATTLE; CELL DIFFERENTIATION; CELL DIVISION; DURAPATITE; GLASS; MATERIALS TESTING; MESODERM; METATARSAL BONES; MODELS, ANIMAL; OSSEOINTEGRATION; OSTEOGENESIS; PROSTHESIS IMPLANTATION; RATS; RATS, WISTAR; TITANIUM;

EID: 0037026411     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.10216     Document Type: Article

References (39)

1. A rationale for the delivery of osteoinductive proteins
2. Poly(α-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology
3. Exploiting glycation to stiffen and strengthen tissue equivalents for tissue engineering
4. Bone formation in calcium-phosphate-coated titanium mesh
5. Ectopic bone formation in BMP-loaded CaP-coated titanium fiber mesh
6. Cell biology and biochemistry of endochondral bone development
7. BMPs induce direct bone formation in ectopic sites independent of the endochondral ossification in vivo
8. Two distinctive BMP-carriers induce zonal chondrogenesis and membranous ossification, respectively; geometrical factors of matrices for cell-differentiation
9. BMPs induce endochondral ossification in rats when implanted ectopically within a carrier made of fibrous glass membrane
10. Effects of geometry of hydroxyapatite as a cell substratum in BMP- induced ectopic bone formation
11. Application of magnetron sputtering for producing ceramic coatings on implant materials
12. Osteogenesis induced by BMP-coated biomaterials: Biochemical principles of bone reconstruction in dentistry
13. Comparative histological studies of bone and cartilage formations induced by various carrier composites
14. Preparation of hydroxyapatite by the hydrolysis of brushite
15. A new porous hydroxyapatite ceramic prepared by cold isostatic pressing and sintering synthesized flaky powder
16. Bone formation in osteoporotic rats, reduced effect of bone morphogenetic protein ascribed to the suppressed osteoblast differentiation
17. A simple method for preparing thin (10 μM) histological sections of undecalcified plastic embedded bone with implants
18. Tissue reaction to soft-tissue anchored percutaneous implants in rabbits
19. Wound healing phenomena in titanium fibre mesh: The influence of the length of implantation
20. Purification of bovine bone morphogenetic protein by hydroxyapatite chromatography
21. Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation
22. Matrix-induced endochondral bone differentiation: Influence of hypophysectomy, growth hormone, and thyroid-stimulating hormone
23. Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model
24. Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model
25. Constitution of bone inducing implants by combining bone morphogenetic protein with biomaterials: Experimental studies in mice
26. Evaluation of polylactic acid homopolymers as carriers for bone morphogenetic protein
27. BMP-induced osteogenesis on the surface of hydroxyapatite with geometrically feasible and nonfeasible structures: Topology of osteogenesis
28. Recombinant human bone morphogenetic protein induces bone formation
29. Cartilage begets bone versus endochondral myelopoiesis
30. Antiangiogenic agent (TNP-470) inhibition of ectopic bone formation induced by bone morphogenetic protein-2
31. The role of the vessels in osteogenesis
32. Vascular pericytes express osteogenic potential in vitro and in vivo
33. Influence of oxygen concentration and mechanical factors on differentiation of connective tissues in vitro
34. Hypoxia and differentiation of cartilage and bone from common germinal cells in vitro
35. The cellular and molecular embryology of bone formation
36. Geometric effect of matrix upon cell differentiation: BMP-induced osteogenesis using a new bioglass with a feasible structure
37. Hydroxyapatite-coated titanium mesh as a tissue engineered carrier of BMP induced osteogenesis
38. Rationale for hydroxyapatite-coated titanium mesh as an effective carrier for BMP
39. Tissue engineered bone grafts