Development of monoclonal antibodies specific for Ricinus agglutinins

Food and Agricultural Immunology

Volumn 20, Issue 1, 2009, Pages 11-22

  Brandon, David L ^a   Hernlem, Bradley J ^a  

^a WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

Castor; Monoclonal antibody; Ricin; Ricinus communis agglutinin

Indexed keywords

RICINUS COMMUNIS;

EID: 60849116703     PISSN: 09540105     EISSN: 14653443     Source Type: Journal    
DOI: 10.1080/09540100802626487     Document Type: Article

References (22)

1. Chen, G.Q., He, X., & McKeon, T.A. (2005). A simple and sensitive assay for distinguishing the expression of ricin and Ricinus communis agglutinin genes in developing castor seed (R. communis L.). Journal of Agricultural and Food Chemistry, 53, 2358-2361.
2. Dierks, S.E., Butler, J.E., & Richerson, H.B. (1986). Altered recognition of surface-adsorbed compared to antigen-bound antibodies in the ELISA. Molecular Immunology, 23, 403-411.
3. Doan, L.G. (2004). Ricin: Mechanism of toxicity, clinical manifestations, and vaccine development. A review. Journal of Toxicology: Clinical Toxicology, 42, 201-208.
4. Fredriksson, S.A., Hulst, A.G., Artursson, E., de Jong, A.L., Nilsson, C., & van Baar, B.L. (2005). Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry. Analytical Chemistry, 77, 1545-1555.
5. Garber, E.A.E. (2008). Toxicity and detection of ricin and abrin in beverages. Journal of Food Protection, 71, 1875-1883.
6. Garber, E.A.E., Eppley, R.M., Stack, M.E., McLaughlin, M.A., & Park, D.L. (2005). Feasibility of immunodiagnostic devices for the detection of ricin, amanitin, and T-2 toxin in food. Journal of Food Protection, 68, 1294-1301.
7. Hale, M.L. (2001). Microtiter-based assay for evaluating the biological activity of ribosomein-activating proteins. Pharmacology & Toxicology, 88, 255-260.
8. He, X., Lu, S., Cheng, L.W., Rasooly, R., & Carter, J.M. (2008). Effect of food matrices on the biological activity of ricin. Journal of Food Protection, 71, 2053-2058.
9. Hines, H.B., Brueggemann, E.E., & Hale, M.L. (2004). High-performance liquid chromatography-mass selective detection assay for adenine released from a synthetic RNA substrate by ricin A chain 4719. Anaytical Biochemistry, 330, 119-122.
10. Ishiguro, M., Tanabe, S., Matori, Y., & Sakakibara, R. (1992). Biochemical studies on oral toxicity of ricin. IV. A fate of orally administered ricin in rats. Journal of Pharmacobio-Dynamics, 15, 147-156.
11. Krolick, K.A., Villemez, C., Isakson, P., Uhr, J.W., & Vitetta, E.S. (1980). Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin. Proceedings of the National Academy of Sciences USA, 77, 5419-5423.
12. Lord, J.M., & Lynne, M.R. (2005). Ricin: Structure, synthesis, and mode of action. In M.J. Schmitt & R. Schaffrath (Eds.), Microbial protein toxins (pp. 215-233). Berlin, Germany: Springer-Verlag.
13. Maddaloni, M., Cooke, C., Wilkinson, R., Stout, A.V., Eng, L., & Pincus, S.H. (2004). Immunological characteristics associated with the protective efficacy of antibodies to ricin. Journal of Immunology, 172, 6221-6228.
14. Madsen, J.M. (2001). Toxins as weapons of mass destruction. A comparison and contrast with biological-warfare and chemical-warfare agents. Clinics in Laboratory Medicine, 21, 593-605.
15. Na, D.H., Cho, C.K., Youn, Y.S., Choi, Y., Lee, K.R., Yoo, S.D., & Lee, K.C. (2004). Capillary electrophoresis to characterize ricin and its subunits with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Toxicon, 43, 329-335.
16. Poli, M.A., Rivera, V.R., Hewetson, J.F., & Merrill, G.A. (1994). Detection of ricin by colorimetric and chemiluminescence ELISA. Toxicon, 32, 1371-1377.
17. Shyu, H.F., Chiao, D.J., Liu, H.W., & Tang, S.S. (2002). Monoclonal antibody-based enzyme immunoassay for detection of ricin. Hybridoma and Hybridomics, 21, 69-73.
18. Shyu, R.H., Shyu, H.F., Liu, H.W., & Tang, S.S. (2002). Colloidal gold-based immunochromatographic assay for detection of ricin. Toxicon, 40, 255-258.
19. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., & Klenk, D.C. (1985). Measurement of protein using bicinchoninic acid. Analytical Biochemistry, 150, 76-85.
20. Stine, R., Pishko, M.V., & Schengrund, C.L. (2005). Comparison of glycosphingolipids and antibodies as receptor molecules for ricin detection. Analytical Chemistry, 77, 2882-2888.
21. Sugasawara, R.J., Cahoon, B.E., & Karu, A.E. (1985). The influence of murine macrophage-conditioned medium on cloning efficiency, antibody synthesis, and growth rate of hybridomas. Journal of Immunological Methods, 79, 263-275.
22. Zhan, J., & Zhou, P. (2003). A simplified method to evaluate the acute toxicity of ricin and Ricinus agglutinin. Toxicology, 186, 119-123.