Patterns of hepatoblastoma and hepatocellular carcinoma in children after universal hepatitis b vaccination in Taiwan: A report from a single institution in Southern Taiwan

Journal of Pediatric Hematology/Oncology

Volumn 31, Issue 2, 2009, Pages 91-96

  Hsiao, Chih Cheng ^a   Chuang, Jiin Haur ^a,b   Tiao, Mao Ming ^a   Sheen, Jiunn Ming ^a   Shieh, Chie Song ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Anemia; Children; Hepatoblastoma; Hepatocellular carcinoma; Thrombocytosis

Indexed keywords

ALPHA FETOPROTEIN; CISPLATIN; DOXORUBICIN; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IFOSFAMIDE;

ADOLESCENT; ARTICLE; BRAIN METASTASIS; CANCER CHEMOTHERAPY; CANCER STAGING; CANCER SURGERY; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE FREE SURVIVAL; FEMALE; HEPATITIS B; HEPATOBLASTOMA; HUMAN; HUMAN TISSUE; INFANT; LIVER CELL CARCINOMA; LIVER RESECTION; LUNG METASTASIS; MALE; MEDICAL RECORD REVIEW; MICROCYTIC ANEMIA; MULTIPLE CYCLE TREATMENT; NEEDLE BIOPSY; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TAIWAN; THROMBOCYTOSIS; TREATMENT OUTCOME; VACCINATION; ANEMIA; BLOOD; MORTALITY; RETROSPECTIVE STUDY; SURVIVAL; VIROLOGY;

ALPHA-FETOPROTEINS; ANEMIA; CARCINOMA, HEPATOCELLULAR; CHILD; CHILD, PRESCHOOL; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HEPATOBLASTOMA; HUMANS; INFANT; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TAIWAN; THROMBOCYTOSIS;

EID: 60849111149     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31818b3784     Document Type: Article

References (39)

1. Chen WJ, Lee JC, Hung WT. Primary malignant tumor of liver in infants and children in Taiwan. J Pediatr Surg. 1988;23: 457-461.
2. Wu TC, Tong MJ, Hwang B, et al. Primary hepatocellular carcinoma and hepatitis B infection during childhood. Hepatology. 1987;7:46-48.
3. Lee CL, Hsieh KS, Ko YC. Trends in the incidence of hepatocellular carcinoma in boys and girls in Taiwan after large-scale hepatitis B vaccination. Cancer Epidemiol Biomarkers Prev. 2003;12:57-59.
4. Lee CL, Ko YC. Survival and distribution pattern of childhood liver cancer in Taiwan. Eur J Cancer. 1998;34: 2064-2067.
5. Chang MH, Chen CJ, Lai MS, et al. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Engl J Med. 1997;336:1855-1859.
6. Chang MH, Chen TH, Hsu HM, et al. Taiwan Childhood HCC Study Group. Prevention of hepatocellular carcinoma by universal vaccination against hepatitis B virus: the effect and problems. Clin Cancer Res. 2005;11:7953-7957.
7. Pham TH, Iqbal CW, Grams JM, et al. Outcomes of primary liver cancer in children: an appraisal of experience. J Pediatr Surg. 2007;42:834-839.
8. Chen PH, Lin YC, Tu HP, et al. Important prognostic factors for the long-term survival of subjects with primary liver cancer in Taiwan: a hyperendemic area. Eur J Cancer. 2007;43: 1076-1084.
9. Tsai HL, Liu CS, Chin TW, et al. Hepatoblastoma and hepatocellular carcinoma in children. J Chin Med Assoc. 2004;67:83-88.
10. Chiu SN, Ni YH, Lu MY, et al. A trend of improved survival of childhood hepatoblastoma treated with cisplatin and doxorubicin in Taiwanese children. Pediatr Surg Int. 2003; 19:593-597.
11. Udupa KV, Navadgi SM, Mullerpatan P, et al. Neoadjuvant chemotherapy before surgery of hepatoblastoma. Indian J Pediatr. 2006;73:735-737.
12. Tiao GM, Bobey N, Allen S, et al. The current management of hepatoblastoma: a combination of chemotherapy, conventional resection, and liver transplantation. J Pediatr. 2005;146: 204-211.
13. Urata H, Hori H, Uchida K, et al. Strategy for the treatment of unresectable hepatoblastoma: neoadjuvant chemotherapy followed by delayed primary operation or liver transplantation. Int Surg. 2004;89:95-99.
14. Schnater J, Aronson DC, Plaschkes J, et al. Surgical view of the treatment of patients with hepatoblastoma: results from the first prospective trial of the International Society of Pediatric Oncology Liver Tumor Study Group. Cancer. 2002;94: 1111-1120.
15. Katzenstein HM, London WB, Douglass EC, et al. Treatment of unresectable and metastatic hepatoblastoma: a pediatric oncology group phase II study. J Clin Oncol. 2002;20: 3438-3444.
16. Chen JC, Chen CC, Chen WJ, et al. Hepatocellular carcinoma in children: clinical review and comparison with adult cases. J Pediatr Surg. 1998;33:1350-1354.
17. Chen JC, Chang ML, Lin JN, et al. Comparison of childhood hepatic malignancies in a hepatitis B hyper-endemic area. World J Gastroenterol. 2005;11:5289-5294.
18. Ni YH, Chang MH, Hsu HY, et al. Hepatocellular carcinoma in childhood. Clinical manifestations and prognosis. Cancer. 1991;68:1737-1741.
19. Chen HL, Chang MH, Ni YH, et al. Seroepidemiology of hepatitis B virus infection in children: Ten years of mass vaccination in Taiwan. JAMA. 1996;276:906-908.
20. Chang MH, Shau WY, Chen CJ, et al. Taiwan Childhood Hepatoma Study Group. Hepatitis B vaccination and hepatocellular carcinoma rates in boys and girls. JAMA. 2000;284: 3040-3042.
21. Ni YH, Huang LM, Chang MH, et al. Two decades of universal hepatitis B vaccination in Taiwan: impact and implication for future strategies. Gastroenterology. 2007;132: 1287-1293.
22. Kee KM, Wang JH, Lee CM, et al. Validation of clinical AJCC/UICC TNM staging system for hepatocellular carcinoma: analysis of 5613 cases from a medical center in southern Taiwan. Int J Cancer. 2007;120:2650-2655.
23. Chan KL, Fan ST, Tam PK, et al. Paediatric hepatoblastoma and hepatocellular carcinoma: retrospective study. Hong Kong Med J. 2002;8:13-17.
24. Hwang SJ, Luo JC, Li CP, et al. Thrombocytosis: a paraneoplastic syndrome in patients with hepatocellular carcinoma. World J Gastroenterol. 2004;10:2472-2477.
25. Kuo CY, Liu HC, Chang MH, et al. Hepatoblastoma in infancy and childhood: a clinical and pathological study of 32 cases. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1991; 32:79-87.
26. Komura-Naito E, Matsumura T, Sawada T, et al. Thrombopoie-tin in patients with hepatoblastoma. Blood. 1997;90:2849-2850.
27. Nickerson HJ, Silberman TL, McDonald TP. Hepatoblastoma, thrombocytosis, and increased thrombopoietin. Cancer. 1980;45:315-317.
28. Gara S, Ghanem A, Jmal A, et al. Erythropoietin in cancer patients with anemia. Tunis Med. 2007;85:131-133.
29. Michael JG, Stuart W, Smellie A. Investigating iron status in microcytic anaemia. BMJ. 2006;333:791-793.
30. Weizer-Stern O, Adamsky K, Margalit O, et al. Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53. Br J Haematol. 2007;138:253-262.
31. Rivera S, Liu L, Nemeth E, et al. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005;105:1797-1802.
32. von Schweinitz D, Hadam MR, Welte K, et al. Production of interleukin-1 beta and interleukin-6 in hepatoblastoma. Int J Cancer. 1993;53:728-734.
33. Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 2006;108:3204-3209.
34. Czauderna P, Otte JB, Aronson DC, et al. Childhood Liver Tumour Strategy Group of the International Society of Paediatric Oncology (SIOPEL). Guidelines for surgical treatment of hepatoblastoma in the modern era - recommendations from the Childhood Liver Tumour Strategy Group of the International Society of Paediatric Oncology (SIOPEL). Eur J Cancer. 2005;41:1031-1036.
35. Pritchard J, Brown J, Shafford E, et al. Cisplatin, doxorubicin, and delayed surgery for childhood hepatoblastoma: a successful approach - results of the first prospective study of the International Society of Pediatric Oncology. J Clin Oncol. 2000;18:3819-3828.
36. Ortega JA, Douglass EC, Feusner JH, et al. Randomized comparison of cisplatin/vincristine/fluorouracil and cisplatin/ continuous infusion doxorubicin for treatment of pediatric hepatoblastoma: a report from the Children's Cancer Group and the Pediatric Oncology Group. J Clin Oncol. 2000;18: 2665-2675.
37. Fuchs J, Bode U, von Schweinitz D, et al. Analysis of treatment efficiency of carboplatin and etoposide in combination with radical surgery in advanced and recurrent childhood hepatoblastoma: a report of the German Cooperative Pediatric Liver Tumor Study HB 89 and HB 94. Klin Padiatr. 1999;211: 305-309.
38. Sasaki F, Matsunaga T, Iwafuchi M, et al. Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: a report from the Japanese Study Group for Pediatric Liver Tumor. J Pediatr Surg. 2002;37:851-856.
39. Lin CC, Chen CL, Cheng YF, et al. Major hepatectomy in children: approaching blood transfusion-free. World J Surg. 2006;30:1115-1119.