Stereoselective formation of a functionalized dipeptide isostere by zinc carbenoid-mediated chain extension

Journal of Organic Chemistry

Volumn 74, Issue 2, 2009, Pages 645-651

  Lin, Weimin ^a   Theberge, Cory R ^a   Henderson, Timothy J ^a   Zercher, Charles K ^b   Jasinski, Jerry ^c   Butcher, Ray J ^a,b,c  

^a Univ of New Hampshire   (United States)

^b KEENE STATE COLLEGE   (United States)

^c HOWARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOL REACTIONS; CARBENOID; CHAIN EXTENSIONS; CHAIN-EXTENSION REACTIONS; CLEAVAGE SITES; DIASTEREOCONTROL; DIPEPTIDE ISOSTERE; FUNCTIONALIZED; KETO ESTERS; OXAZOLIDINONE; OXIDATIVE CLEAVAGE REACTIONS; PROTECTING GROUPS; SIDE CHAINS; STEREOSELECTIVE FORMATIONS; SYNTHETIC METHODOLOGIES; TANDEM REACTIONS; TETRAPEPTIDE;

AMINES; AMINO ACIDS; ESTERS; ORGANIC ACIDS; STEREOSELECTIVITY; ZINC;

APPLICATIONS;

AMINO ACID; CARBENOID; DIPEPTIDE DERIVATIVE; OXAZOLIDINONE DERIVATIVE; PROTEINASE; TETRAPEPTIDE; ZINC; ASSEMBLIN; BIOMIMETIC MATERIAL; DIETHYLZINC; DIPEPTIDE; ORGANOMETALLIC COMPOUND; SERINE PROTEINASE;

AEROBIC METABOLISM; ALDOL REACTION; ALPHA CHAIN; ANALYTIC METHOD; ARTICLE; CHEMICAL REACTION; DIASTEREOISOMER; HUMAN CYTOMEGALOVIRUS; MOLECULAR MIMICRY; STEREOCHEMISTRY; CATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM; STEREOISOMERISM; SYNTHESIS;

BIOMIMETIC MATERIALS; CATALYSIS; CATALYTIC DOMAIN; DIPEPTIDES; ORGANOMETALLIC COMPOUNDS; SERINE ENDOPEPTIDASES; STEREOISOMERISM;

EID: 60849099932     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo801993k     Document Type: Article

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