Two-dimensional difference gel electrophoresis analysis of streptococcus uberis in response to mutagenesis-lnducing ciprofloxacin challenge

Journal of Proteome Research

Volumn 8, Issue 1, 2009, Pages 246-255

  Poutanen, Marjo ^a   Varhimo, Emilia ^b   Kalkkinen, Nisse ^a   Sukura, Antti ^b   Varmanen, Pekka ^b   Savijoki, Kirsi ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

2 D DIGE; Antibiotic resistance; Ciprofloxacin; Mutagenesis; Streptococcus uberis

Indexed keywords

ADENYLOSUCCINATE SYNTHASE; BACTERIAL DNA; BACTERIAL PROTEIN; CIPROFLOXACIN; DEOXYRIBONUCLEOTIDE; DEOXYRIBOSE; DNA BINDING PROTEIN; DNA POLYMERASE; DNA TOPOISOMERASE IV; IDITOL DEHYDROGENASE; INOSITOL PHOSPHATE; OXIDOREDUCTASE; PHOSPHOGLYCERATE KINASE; PHOSPHOTRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; CARBOCYANINE; CYANINE DYE 3; CYANINE DYE 5; NUCLEOTIDE;

ADAPTATION; AMINO ACID SYNTHESIS; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERIAL VIRULENCE; CARBOHYDRATE METABOLISM; CELL KILLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS INHIBITION; DRUG EFFECT; DRUG EXPOSURE; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; FRAMESHIFT MUTATION; GENE DELETION; GENE INSERTION; GENE OVEREXPRESSION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLISM; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RNA TRANSLATION; STREPTOCOCCUS UBERIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; CHEMISTRY; IMAGE PROCESSING; ISOELECTRIC FOCUSING; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PROTEOMICS; REPRODUCIBILITY; STREPTOCOCCUS;

STREPTOCOCCUS UBERIS;

BASE SEQUENCE; CARBOCYANINES; CIPROFLOXACIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOELECTRIC FOCUSING; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEOTIDES; OXIDATIVE STRESS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STREPTOCOCCUS;

EID: 60849093202     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr800384j     Document Type: Article

References (49)

1. Power, E. G. M.; Phillips, I. Induction of the SOS gene [umuC by 4-quinolone antibacterial drugs. J. Med. Microbiol. 1992, 36, 78-82.
2. Blázquez, J.; Oliver, A.; Gómez-Gómez, J. M. Mutation and evolution of antibiotic resistance: Antibiotics as promoters of antibiotic resistance. Curr. Drug Targets 2002, 3, 345-349.
3. Beaber, J. W.; Hochhut, B.; Waldor, M. K. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 2004, 427, 72-74.
4. Ubeda, C.; Maiques, E.; Knecht, E.; Lasa, I.; Novick, R. P.; Penades, J. R. Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci. Mol. Microbiol. 2005, 56, 836-844.
5. Prudhomme, M.; Attaiech, L.; Sanchez, G.; Martin, B.; Claverys, J. P. Antibiotic stress induces genetic transformability in the human pathogen Streptococcus pneumoniae. Science 2006, 313, 89-92.
6. Cirz, R. T.; Chin, J. K.; Andes, D. R.; de Crecy-Lagard, V.; Craig, W. A.; Romesberg, F. E. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol. 2005, 3, 1024-1033.
7. Cirz, R. T.; Jones, M. B.; Gingles, N. A.; Minogue, T. D.; Jarrahi, B.; Peterson, S. N.; Romesberg, F. E. Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin.J. Bacteriol. 2007, 189, 531-539.
8. Cirz, R. T.; Romesberg, F. E. Induction and inhibition of ciprofloxacin resistance-conferring mutations in hypermutator bacteria. Antimicrob. Agents Chemother. 2006, 50, 220-225.
9. Cirz, R. T.; O'Neill, B. M.; Hammond, J. A.; Head, S. R.; Romesberg, F, E. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J. Bacteriol. 2006, 188, 7101-7110.
10. Henderson-Begg, S. K.; Livermore, D. M.; Hall, L. M. C. Effect of subinhibitory concentrations of antibiotics on mutation frequency in Streptococcus pneumoniae. J. Antimicrob. Chemother. 2006, 57, 849-854.
11. Ysern, P.; Clerch, B.; Castano, M.; Gibert, I.; Barbe, J.; Llagostera, M. Induction of SOS genes in Escherichia coli and mutagenesis in Salmonella typhimurium by fluoroquinolones. Mutagenesis 1990, 5, 63-66.
12. McKellar, Q.; Gibson, I.; Monteiro, A.; Bregante, M. Pharmacokinetics of enrofloxacin and danofloxacin in plasma, inflammatory exudate, and bronchial secretions of calves following subcutaneous administration. Antimicrob. Agents Chemother. 1999, 43, 1988-1992.
13. Grobbel, M.; Lübke-Becker, A.; Wieler, J. H.; Froyman, R.; Fire-derichs, S.; Filios, S. Comparative quantification of the in vitro activity of veterinary fluoroquinolones. Vet. Microbiol. 2007, 124, 73-81.
14. Batt, A. L.; Bruce, I. B.; Aga, D. S. Evaluating the vulnerability of surface waters to antibiotic contamination from varying wastewater treatment plant discharges. Environ. Pollut. 2006,142,295-302.
15. Turiel, E.; Bordin, G.; Rodriguez, A. R. Study of the evolution and degradation products of ciprofloxacin and oxolinic acid in river water samples by HPLC-UV/MS/MS-MS. J. Environ. Monit. 2005, 7, 189-195.
16. Drlica, K. Mechanism of fluoroquinolone action. Curr. Opin. Microbiol. 1999, 2, 504-508.
17. DNA Repair and Mutagenesis; Friedberg, E. C, Walker, G. C, Seide, W., Wood, R. D., Schultz, R. A., Ellenberger, T., Eds.; ASM Press: Washington, DC, 2006.
18. López, E.; Elez, M.; Matic, I.; Blázquez, J. Antibiotic-mediated recombination: ciprofloxacin stimulates SOS-independent recombination of divergent sequences in Escherichia coli. Mol. Microbiol. 2007, 64, 83-93.
19. Gmuender, H.; Kuratli, K.; Di Padova, K.; Gray, C. P.; Keck, W.; Evers, S. Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: combined transcription and translation analysis. Genome Res. 2001, 11, 28-42.
20. Shaw, K. J.; Miller, N.; Liu, X. J.; Lerner, D.; Wan, J.; Bittner, A.; Morrow, B. J. Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents. J. Mol. Microbiol. Biotechnol. 2003, 5, 105-122.
21. Kaldalu, M.; Mei, R.; Lewis, K. Killing by ampicillin and ofloxacin induces overlapping changes in Escherichia coli transcription profile. Antimicrob. Agents Chemother. 2004, 48, 890-896.
22. Marrer, E.; Satoh, A. T.; Johnson, M. M.; Piddock, L. J. V.; Page, M. G. P. Global transcriptome analysis of the responses of a fluoroquinolone-resistant Streptococcus pneumoniae mutant and its parent to ciprofloxacin. Antimicrob. Agents Chemother. 2006, 50, 269-278.
23. Bandow, J. E.; Brotz, H.; Leichert, L. I. O.; Labischinski, H.; Hecker, M. Proteomic approach to understanding antibiotic action. Antimicrob. Agents Chemother. 2003, 47, 948-955.
24. Coldham, N. G.; Randall, L. P.; Piddock, L. J. V.; Woodward, M. J. Effect of fluoroquinolone exposure on the proteome of Salmonella enterica serovar Typhimurium. J. Antimicrob. Chemother. 2006, 58, 1145-1153.
25. Milne, M. H.; Biggs, A. M.; Barrett, D. C; Young, F. J.; Doherty, S.; Innocent, G. T.; Fitzpatrick, J. L. Treatment of persistent intra-mammary infections with Streptococcus uberis in dairy cows. Vet. Rec. 2005, 157, 245-250.
26. Gasc, A. M.; Sicard, N.; Claverys, J. P.; Sicard, A. M. Lack of SOS repair in Streptococcus pneumoniae. Mutat. Res. 1980, 70, 157-165.
27. Varhimo, E.; Savijoki, K.; Jalava, J.; Kuipers, O. P.; Varmanen, P. Identification of a novel streptococcal gene cassette mediating SOS mutagenesis in Streptococcus uberis. J. Bacteriol. 2007,189, 5210-5222.
28. Varhimo, E.; Savijoki, K.; Jefremoff, H.; Jalava, J.; Sukura, A.; Varmanen, P. Ciprofloxacin induces mutagenesis to antibiotic resistance independent of UmuC in Streptococcus uberis. Environ. Microbiol. 2008, 10 (8), 2179-2183.
29. Suokko, A.; Poutanen, M.; Savijoki, K.; Kalkkinen, N.; Varmanen, P. ClpL is essential for induction of thermotolerance and is potentially part of the HrcA regulon in Lactobacillus gasseri. Proteomics 2008, 8, 1029-1041.
30. Poutanen, M.; Salusjarvi, L.; Ruohonen, L.; Penttila, M.; Kalkkinen, N. Use of matrix-assisted laser desorpuon/ionizarion time-of-flight mass mapping and nanospray liquid chromatography/electrospray ionization tandem mass spectrometry sequence tag analysis for high sensitivity identification of yeast proteins separated by two-dimensional gel electrophoresis. Rapid Commun. Mass Spectrom. 2001, 15, 1685-1692.
31. Varmanen, P.; Ingmer, H.; Vogensen, F. K. ctsR of Lactococcus lactis encodes a negative regulator of clp gene expression, microbiology 2000, 146, 1447-1455.
32. Khodursky, A. B.; Cozzarelli, N. R. The mechanism of inhibition of topoisomerase IV by quinolone antibacterials. J. Biol. Chem. 1998, 273, 27668-27677.
33. Khodursky, A. B.; Zechiedrich, E. L.; Cozzarelli, N. R. Topoisomerase IV is a target of quinolones in Escherichia coli. Proc. Nat. Acad. Sci. U.SA. 1995, 92, 11801-11805.
34. Becerra, M. C; Albesa, I. Oxidative stress induced by ciprofloxacin in Staphylococcus aureus. Biochem. Biophys. Res. Commun. 2002, 297, 1003-1007.
35. Kohanski, M. A.; Dwyer, D. J.; Hayete, B.; Lawrence, C. A.; Collins, J. J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 2007, 130, 797-810.
36. Storz, G.; Imlay, J. A. Oxidative stress. Curr. Opin. Microbiol. 1999, 2, 188-194.
37. Jönsson, T. J.; Ellis, H. R.; Poole, L. B. Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system. Biochemistry 2007,46, 5709-5721.
38. Brenot, A.; King, K. Y.; Caparon, M. G. The PerR regulon in peroxide resistance and virulence of Streptococcus pyogenes. Mol. Microbiol. 2005, 55, 221-234.
39. 2 decomposition, and virulence in Streptococcus pyogenes. J. Bacteriol. 2008, 190, 3225-3235.
40. Herbig, A. F.; Helmann, J. D. Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtillis PerR peroxide regulon repressor with operator DNA. Mol. Microbiol. 2001, 41, 849-859.
41. Iwami, Y.; Takahashi-Abbe, S.; Takahashi, N.; Abbe, K.; Yamada, T. Rate-limiting steps of glucose and sorbitol metabolism in Streptococcus mutans cells exposed to air. Oral Microbiol. Immunol. 2000, 15, 325-328.
42. Nordlund, N.; Reichard, P. Ribonucleotide reductases. Annu. Rev. Biochem. 2006, 75, 681-706.
43. Sun, L.; Fuchs, J. A. Escherichia coli ribonucleotide reductase expression is cell cycle regulated. Mol. Biol. Cell. 1992, 3, 1095-1105.
44. Jordan, A.; Torrents, E.; Sala, I.; Hellman, U.; Gibert, I.; Reichard, P. Ribonucleotide reduction in Pseudamonas species: simultaneous presence of active enzymes from different classes. J. Bacteriol. 1999, 181, 3974-3980.
45. Masalha, M.; Borovok, I,; Schreiber, R.; Aharonowitz, Y.; Cohen, G. Analysis of transcription of the Staphylococcus aureus aerobic class lb and anaerobic class III ribonucleotide reductase genes in response to oxygen. J. Bacteriol. 2001, 183, 7260-7272.
46. Sgarrella, F.; Poddie, F. P. A.; Meloni, M. A.; Sciola, L.; Pippia, P.; Tozzi, M. G. Channelling of deoxyribose moiety of exogenous DNA into carbohydrate metabolism: Role of deoxyriboaldolase. Comp. Biochem. 1997, 117, 253-257.
47. Han, T. K.; Zhu, Z. W.; Dao, M. L. Identification, molecular cloning, and sequence analysis of a deoxyribose aldolase in Streptococcus mutans GS-5. Curr. Microbiol 2004, 48, 230-236.
48. Wheeler, L. J.; Rajagopal, I.; Mathews, C. K. Stimulation of mutagenesis by proportional deoxyribonucleoside triphosphate accumulation in Escherichia coli. DNA Repair 2005, 4,1450-1456.
49. Bebenek, K.; Roberts, J. D.; Kunkel, T. A. The effects of dNTP pool imbalances on frameshift fidelity during DNA-replication. J. Biol. Chem. 1992, 267, 3589-3596.