Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles

Technology in Cancer Research and Treatment

Volumn 8, Issue 1, 2009, Pages 61-70

  Kang, Chunsheng ^a,b   Yuan, Xubo ^a   Zhong, Yuel ^b   Pu, Peiyu ^b   Guo, Yanshuang ^a   Albadany, Ammar ^a,b   Yu, Shizhu ^b   Zhang, Zhiyong ^b   Li, Yanhe ^b   Chang, Jin ^a   Sheng, Jing ^a  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

BCNU; Controlled Release; Glioma cells; Nanoparticles; Poly(D,L lactic acid); Targeting therapy; Transferrin

Indexed keywords

CARMUSTINE; DEXAMETHASONE; GADOLINIUM PENTETATE; INDOMETACIN; ITRACONAZOLE; NANOPARTICLE; POLYLACTIC ACID; TECHNETIUM 99M; TRANSFERRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER MODEL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG IMPLANTATION; GLIOMA CELL; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; MALE; NONHUMAN; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEREOTACTIC PROCEDURE; SURVIVAL RATE; TUMOR GROWTH;

EID: 60849090747     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.1177/153303460900800108     Document Type: Article

References (19)

1. Salcman, M. Survival in glioblastoma: historical perspective. Neurosurgery 7, 435-439 (1980).
2. Bohan, E., Glass-Macenka, D. Surgical management of patients with primary brain tumors. Semin Oncol Nurs 20, 240-252 (2004).
3. Brandes, A. A., Fiorentino, M. V. The role of chemotherapy in recurrent malignant gliomas: an overview. Cancer Invest 14, 551-559 (1996).
4. Westphal, M., Hilt, D. C., Bortey, E., Delavault, P., Olivares, R., Warnke, P. C., Whittle, I. R., Jaaskelainen, J., Ram, Z. A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro-oncol 5, 79-88 (2003).
5. Wang, C. H., Li, J., Teo, C. S., Lee, T. The delivery of BCNU to brain tumors. J Control Release 61, 21-41 (1999).
6. Murakami, H., Kobayashi, M., Takeuchi, H., Kawashima Y. Preparation of poly(DL-lactide-co-glycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method. Int J Pharm 187, 143-152 (1999).
7. Loo, T. L., Dion, R. L. Colorimetric method for the determination of 1,3-bis(2-chloroethyl)-1-nitrosourea. J Pharm Sci 54, 809-810 (1965).
8. Pu, P., Liu, X., Liu, A., Cui, J., Zhang Y. Inhibitory effect of antisense epidermal growth factor receptor RNA on the proliferation of rat C6 glioma cells in vitro and in vivo. J Neurosurg 92, 132-139 (2000).
9. Verrecchia, T., Spenlehauer, G., Bazile, D.V., Mirry-Brelier, A., Ar-chimbaud, Y., Veillard, M. Non-stealth (poly(lactic acid)/albumin)) and stealth (poly(lactic acid-polyethylene glycol)) nanoparticles as injectable drug carrier. J Control Release 36, 49-61 (1995).
10. Painbeni, T., Venier-Julienne, M. C., Benoit, J. Internal morphology of poly(D,L-lactide-co-glycolide) BCNU-loaded microspheres. Influence on drug stability. Euro J Pharm Biopharm 45, 31-39 (1995).
11. Wiencke, J. K., Wiemels, J. Genotoxicity of 1,3-bis(2-chloroethyl)-1- nitrosourea (BCNU). Mutat Res 339, 91-119 (1995).
12. Fessi, H., Puisieux, F., Devissaguet, J. P., Ammoury, N., Benita, S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int J Pharm 55, 1-4 (1989).
13. Magenheim, B., Levy, M. Y., Benita, S. A new in vitro technique for the evaluation of drug release profile from colloidal carriers-ultrafil- tration technique at low pressure. Int J Pharm 94, 115-123 (1993).
14. Chasteigner, S., Fessi, H., Devissaguet, J. P., Puisieux, F. Comparative study of the association of itraconazole with colloidal drug carriers. Drug Dev Res 38, 125-133 (1996).
15. Sipos, E. P., Tyler, B., Piantadosi, S., Burger, P. C., Brem, H. Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemother Pharmacol 39, 383-389 (1997).
16. Brem H., Gabikian P. Biodegradable polymer implants to treat brain tumors. J Control Release 74, 63-67 (2001).
17. Govender, T., Riley, T., Ehtezazi, T., Garnett, M. C., Stolnik, S., Illum, L., Davis, S. S. Defining the drug incorporation properties of PLA-PEG nanoparticles. Int J Pharm 199, 95-110 (2000).
18. Shi, N., Boado, R. J., Pardridge W. M. Receptor-mediated gene targeting to tissues in vivo following intravenous administration of pe-gylated immunoliposomes. Pharm Res 18, 1091-1095 (2001).
19. Cruz, M. T., Simoes, S., Limaa, M. C. Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons. Exp Neurol 187, 65-75 (2000).