Total syntheses of casuarine and its 6-O-α-glucoside: Complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families

Chemistry - A European Journal

Volumn 15, Issue 7, 2009, Pages 1627-1636

  Cardona, Francesca ^a   Parmeggiani, Camilla ^a   Faggi, Enrico ^a   Bonaccini, Claudia ^a   Gratteri, Paola ^a   Sim, Lyann ^b   Gloster, Tracey M ^c   Roberts, Shirley ^c   Davies, Gideon J ^c   Rose, David R ^b   Goti, Andrea ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Enzyme structures; Maltase glucoamylase natural products; Total synthesis; Trehalase

Indexed keywords

CATALYSTS; COMPLEXATION; SUGARS; SYNTHESIS (CHEMICAL);

BIOLOGICAL ASSAYS; CATALYTIC SITES; ENZYME STRUCTURES; GLUCOSYLATION; GLYCOSIDE HYDROLASES; MALTASE GLUCOAMYLASE NATURAL PRODUCTS; NITRONE; STEREO-SELECTIVE; STRUCTURAL DETERMINATIONS; TOTAL SYNTHESIS; TREHALASE;

ENZYMES;

ALKALOID; CASUARINE; ENZYME INHIBITOR; GLUCAN 1,4 ALPHA GLUCOSIDASE; GLUCOSIDE; GLYCOSIDASE; PYRROLE DERIVATIVE; TREHALASE;

ARTICLE; ENZYME ACTIVE SITE; HYDROGEN BOND; KINETICS; METABOLISM; SYNTHESIS;

ALKALOIDS; CATALYTIC DOMAIN; ENZYME INHIBITORS; GLUCAN 1,4-ALPHA-GLUCOSIDASE; GLUCOSIDES; GLYCOSIDE HYDROLASES; HYDROGEN BONDING; KINETICS; PYRROLES; TREHALASE;

EID: 60749132180     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200801578     Document Type: Article

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