메뉴 건너뛰기




Volumn 72, Issue 5, 2009, Pages 345-349

Cytotoxicity screening for the cyanobacterial toxin cylindrospermopsin

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BACTERIAL TOXIN; CYLINDROSPERMOPSIN; DRUG DERIVATIVE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; URACIL;

EID: 60749114769     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802529906     Document Type: Article
Times cited : (52)

References (23)
  • 1
    • 34548363323 scopus 로고    scopus 로고
    • Induction of p53-regulated gene expression in human cell lines exposed to the cyanobacterial toxin cylindrospermopsin
    • Bain, P., Shaw, G., and Patel, B. 2007. Induction of p53-regulated gene expression in human cell lines exposed to the cyanobacterial toxin cylindrospermopsin. J. Toxicol. Environ. Health A 70:1687-1693.
    • (2007) J. Toxicol. Environ. Health A , vol.70 , pp. 1687-1693
    • Bain, P.1    Shaw, G.2    Patel, B.3
  • 2
    • 0036027412 scopus 로고    scopus 로고
    • Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes
    • Chong, M. W. K., Wong, B. S. F., Lam, P. K. S., Shaw, G. R., and Seawright, A. A. 2002. Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes. Toxicon 40:205-211.
    • (2002) Toxicon , vol.40 , pp. 205-211
    • Chong, M.W.K.1    Wong, B.S.F.2    Lam, P.K.S.3    Shaw, G.R.4    Seawright, A.A.5
  • 3
    • 0033034115 scopus 로고    scopus 로고
    • Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice
    • Falconer, I. R., Hardy, S. J., Humpage, A. R., Froscio, S. M., Tozer, G. J., and Hawkins, P. R. 1999. Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss albino mice. Environ. Toxicol. 14:143-150.
    • (1999) Environ. Toxicol , vol.14 , pp. 143-150
    • Falconer, I.R.1    Hardy, S.J.2    Humpage, A.R.3    Froscio, S.M.4    Tozer, G.J.5    Hawkins, P.R.6
  • 4
    • 38149025634 scopus 로고    scopus 로고
    • Interaction of the cyanobacterial toxin cylindrospermopsin with the eukaryotic protein synthesis system
    • Froscio, S., Humpage, A. R., Wickramasinghe, W., Shaw, G., and Falconer, I. R. 2008. Interaction of the cyanobacterial toxin cylindrospermopsin with the eukaryotic protein synthesis system. Toxicon 51:191-198.
    • (2008) Toxicon , vol.51 , pp. 191-198
    • Froscio, S.1    Humpage, A.R.2    Wickramasinghe, W.3    Shaw, G.4    Falconer, I.R.5
  • 5
    • 0042978772 scopus 로고    scopus 로고
    • Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes
    • Froscio, S. M., Humpage, A. R., Burcham, P. C., and Falconer, I. R. 2003. Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes. Environ. Toxicol. 18:243-251.
    • (2003) Environ. Toxicol , vol.18 , pp. 243-251
    • Froscio, S.M.1    Humpage, A.R.2    Burcham, P.C.3    Falconer, I.R.4
  • 6
    • 0031106797 scopus 로고    scopus 로고
    • Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake
    • Hawkins, P. R., Chandrasena, N. R., Jones, G. J., Humpage, A. R., and Falconer, I. R. 1997. Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon 35:341-346.
    • (1997) Toxicon , vol.35 , pp. 341-346
    • Hawkins, P.R.1    Chandrasena, N.R.2    Jones, G.J.3    Humpage, A.R.4    Falconer, I.R.5
  • 7
    • 0034695122 scopus 로고    scopus 로고
    • Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin
    • Humpage, A. R., Fenech, M., Thomas, P., and Falconer, I. R. 2000. Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutat. Res. 472:155-161.
    • (2000) Mutat. Res , vol.472 , pp. 155-161
    • Humpage, A.R.1    Fenech, M.2    Thomas, P.3    Falconer, I.R.4
  • 8
    • 19544371754 scopus 로고    scopus 로고
    • Cylindrospermopsin genotoxicity and cytotoxicity: Role of cytochrome P-450 and oxidative stress
    • Humpage, A. R., Fontaine, F., Froscio, S., Burcham, P., and Falconer, I. R. 2005. Cylindrospermopsin genotoxicity and cytotoxicity: Role of cytochrome P-450 and oxidative stress. J. Toxicol.Environ.Health A 68:739-753.
    • (2005) J. Toxicol.Environ.Health A , vol.68 , pp. 739-753
    • Humpage, A.R.1    Fontaine, F.2    Froscio, S.3    Burcham, P.4    Falconer, I.R.5
  • 9
    • 34447504634 scopus 로고    scopus 로고
    • Application of the neuroblastoma assay for paralytic shellfish poisons to neurotoxic freshwater cyanobacteria: Interlaboratory calibration and comparison with other methods of analysis
    • Humpage, A. R., Ledreux, A., Fanok, S., Bernard, C., Briand, J. F., Eaglesham, G., Papageorgiou, J., Nicholson, B., and Steffensen, D. 2007. Application of the neuroblastoma assay for paralytic shellfish poisons to neurotoxic freshwater cyanobacteria: Interlaboratory calibration and comparison with other methods of analysis. Environ Toxicol Chem 26:1512-1519.
    • (2007) Environ Toxicol Chem , vol.26 , pp. 1512-1519
    • Humpage, A.R.1    Ledreux, A.2    Fanok, S.3    Bernard, C.4    Briand, J.F.5    Eaglesham, G.6    Papageorgiou, J.7    Nicholson, B.8    Steffensen, D.9
  • 10
    • 0028930642 scopus 로고
    • Toxicological evaluation of saxitoxin, neosaxitoxin, gontautoxin II, gonyautoxin II plus III, and decarbomoylsaxitoxin wiith the mouse neuroblastoma cell bioassay
    • Jellett, J., Stewart, J. E., and Laycock, M. V. 1995. Toxicological evaluation of saxitoxin, neosaxitoxin, gontautoxin II, gonyautoxin II plus III, and decarbomoylsaxitoxin wiith the mouse neuroblastoma cell bioassay. Toxicol. In Vitro 9:57-65.
    • (1995) Toxicol. In Vitro , vol.9 , pp. 57-65
    • Jellett, J.1    Stewart, J.E.2    Laycock, M.V.3
  • 11
    • 0026799204 scopus 로고
    • Paralytic shellfish poison (saxitoxin family) bioassays: Automated endpoint determination and standardization of the in vitro tissue culture bioassay, and comparison with the standard mouse bioassay
    • Jellett, J. F., Marks, L. J., Stewart, J. E., Dorey, M. L., Watson-Wright, W., and Lawrence, J. F. 1992. Paralytic shellfish poison (saxitoxin family) bioassays: Automated endpoint determination and standardization of the in vitro tissue culture bioassay, and comparison with the standard mouse bioassay. Toxicon 30:1143-1156.
    • (1992) Toxicon , vol.30 , pp. 1143-1156
    • Jellett, J.F.1    Marks, L.J.2    Stewart, J.E.3    Dorey, M.L.4    Watson-Wright, W.5    Lawrence, J.F.6
  • 12
    • 0028786481 scopus 로고
    • The human intestinal epithelial cell line Caco-2; Pharmacological and phamacokinetic applications
    • Meunier, V., Bourrié, M., Berger, Y., and Fabre, G. 1995. The human intestinal epithelial cell line Caco-2; Pharmacological and phamacokinetic applications. Cell Biol. Toxicol. 11:187-194.
    • (1995) Cell Biol. Toxicol , vol.11 , pp. 187-194
    • Meunier, V.1    Bourrié, M.2    Berger, Y.3    Fabre, G.4
  • 13
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-56.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-56
    • Mosmann, T.1
  • 14
    • 34548311604 scopus 로고    scopus 로고
    • Studies of the comparative in vitro toxicology of the cyanobacterial metabolite deoxycylindrospermopsin
    • Neumann, C., Bain, P., and Shaw, G. 2007. Studies of the comparative in vitro toxicology of the cyanobacterial metabolite deoxycylindrospermopsin. J. Toxicol. Environ. Health A 70:1679-1686.
    • (2007) J. Toxicol. Environ. Health A , vol.70 , pp. 1679-1686
    • Neumann, C.1    Bain, P.2    Shaw, G.3
  • 15
    • 0028352665 scopus 로고
    • The role of glutathione in the toxicity of a novel cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
    • Runnegar, M. T., Kong, S. M., Zhong, Y. Z., Ge, J. L., and Lu, S. C. 1994. The role of glutathione in the toxicity of a novel cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Biochem. Biophys. Res. Commun. 201:235-241.
    • (1994) Biochem. Biophys. Res. Commun , vol.201 , pp. 235-241
    • Runnegar, M.T.1    Kong, S.M.2    Zhong, Y.Z.3    Ge, J.L.4    Lu, S.C.5
  • 16
    • 0028853288 scopus 로고
    • Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
    • Runnegar, M. T., Kong, S. M., Zhong, Y. Z., and Lu, S. C. 1995. Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes. Biochem. Pharmacol. 49:219-225.
    • (1995) Biochem. Pharmacol , vol.49 , pp. 219-225
    • Runnegar, M.T.1    Kong, S.M.2    Zhong, Y.Z.3    Lu, S.C.4
  • 17
    • 0036094367 scopus 로고    scopus 로고
    • In vitro hepatotoxicity of the cyanobacterial alkaloid cylindrospermopsin and related synthetic analogues
    • Runnegar, M. T., Xie, C. Y., Snider, B. B., Wallace, G. A., Weinreb, S. M., and Kuhlenkamp, J. 2002. In vitro hepatotoxicity of the cyanobacterial alkaloid cylindrospermopsin and related synthetic analogues. Toxicol. Sci 67:81-87.
    • (2002) Toxicol. Sci , vol.67 , pp. 81-87
    • Runnegar, M.T.1    Xie, C.Y.2    Snider, B.B.3    Wallace, G.A.4    Weinreb, S.M.5    Kuhlenkamp, J.6
  • 18
    • 17044428850 scopus 로고    scopus 로고
    • Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II. Mechanistic assays on NAD(P)H, ATP and DNA contents
    • Schoonen, W. G. E. J., de Roos, J. A. D. M., Westerink, W. M. A., and Débiton, E. 2005a. Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II. Mechanistic assays on NAD(P)H, ATP and DNA contents. Toxicol. In Vitro 19:491-503.
    • (2005) Toxicol. In Vitro , vol.19 , pp. 491-503
    • Schoonen, W.G.E.J.1    de Roos, J.A.D.M.2    Westerink, W.M.A.3    Débiton, E.4
  • 19
    • 17044433346 scopus 로고    scopus 로고
    • Cytotoxic effects of 100 reference compounds on HepG2 and HeLa cells and of 60 reference compounds on ECC-1 and CHO cells. I Mechanistic assays on ROS, glutathione depletion and calcein uptake
    • Schoonen, W. G. E. J., Westerink, W. M. A., de Roos, J. A. D. M., and Débiton, E. 2005b. Cytotoxic effects of 100 reference compounds on HepG2 and HeLa cells and of 60 reference compounds on ECC-1 and CHO cells. I Mechanistic assays on ROS, glutathione depletion and calcein uptake. Toxicol. In Vitro 19:505-516.
    • (2005) Toxicol. In Vitro , vol.19 , pp. 505-516
    • Schoonen, W.G.E.J.1    Westerink, W.M.A.2    de Roos, J.A.D.M.3    Débiton, E.4
  • 20
    • 0028200062 scopus 로고
    • Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans
    • Terao, K., Ohmori, S., Igarashi, K., Ohtani, I., Watanabe, M. F., Harada, K. I., Ito, E., and Watanabe, M. 1994. Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans. Toxicon 32:833-843.
    • (1994) Toxicon , vol.32 , pp. 833-843
    • Terao, K.1    Ohmori, S.2    Igarashi, K.3    Ohtani, I.4    Watanabe, M.F.5    Harada, K.I.6    Ito, E.7    Watanabe, M.8
  • 21
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells
    • Westerink, W. M. A., and Schoonen, W. G. E. J. 2007a. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicol. In Vitro 21:1581-1591.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.A.1    Schoonen, W.G.E.J.2
  • 22
    • 36148949386 scopus 로고    scopus 로고
    • Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepaocytes and their induction in HepG2 cells
    • Westerink, W. M. A., and Schoonen, W. G. E. J. 2007b. Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepaocytes and their induction in HepG2 cells. Toxicol In Vitro 21:1592-1602.
    • (2007) Toxicol In Vitro , vol.21 , pp. 1592-1602
    • Westerink, W.M.A.1    Schoonen, W.G.E.J.2
  • 23
    • 11244346943 scopus 로고    scopus 로고
    • Hepatotoxic cyanobacteria: A review of the biological importance of microcystins in freshwater environments
    • Zurawell, R. W., Huirong, C., Burke, J. M., and Prepas, E. E. 2005. Hepatotoxic cyanobacteria: A review of the biological importance of microcystins in freshwater environments. J. Toxicol. Environ. Health B 8:1-37.
    • (2005) J. Toxicol. Environ. Health B , vol.8 , pp. 1-37
    • Zurawell, R.W.1    Huirong, C.2    Burke, J.M.3    Prepas, E.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.