Macrolide-lincosamide-streptogramin B resistant phenotypes and genotypes for methicillin-resistant staphylococcus aureus in Turkey, from 2003 to 2006

Polish Journal of Microbiology

Volumn 57, Issue 4, 2008, Pages 307-312

  Gul, H Cem ^a   Kilic, Abdullah ^a   Guclu, Aylin Uskudar ^a   Bedir, Orhan ^a   Orhon, Mustafa ^a   Basustaoglu, A Celal ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

MLSB; MRSA; Multiplex real time PCR; Staphylococcus aureus

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; BACTERIAL PROTEIN; CEFAZOLIN; CLINDAMYCIN; COTRIMOXAZOLE; DALFOPRISTIN PLUS QUINUPRISTIN; ERYTHROMYCIN; GENTAMICIN; LEVOFLOXACIN; LINCOSAMIDE; LINEZOLID; MACROLIDE; METHIONINE SULFOXIDE REDUCTASE A; MIKAMYCIN B; MINOCYCLINE; PENICILLIN G; PROTEIN ERMA; PROTEIN ERMC; RIFAMPICIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ACCURACY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE IDENTIFICATION; GENOME ANALYSIS; GENOTYPE PHENOTYPE CORRELATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; TREND STUDY; TURKEY (REPUBLIC);

ADULT; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CHILD; CLINDAMYCIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ERYTHROMYCIN; FEMALE; GENES, BACTERIAL; GENOTYPE; HUMANS; LINCOSAMIDES; MALE; MEMBRANE TRANSPORT PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; PHENOTYPE; POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; STREPTOGRAMIN B; TURKEY;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 60749110466     PISSN: 17331331     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Aktas Z., A. Aridogan, C.B. Kayacan and D. Aydin. 2007. Resistance to macrolide, lincosamide and streptogramin antibiotics in staphylococci isolated in Istanbul, Turkey. J. Microbiol. 45: 286-290.
2. Angel M.R., V. Balaji, J. Prakash, K.N. Brahmadathan and M.S. Mathews. 2008. Prevalence of inducible clindamycin resistance in gram positive organisms in a tertiary care centre. Indian J. Med. Microbiol. 26: 262-264.
3. Ardic N., M. Ozyurt, B. Sareyyupoglu and T. Haznedaroglu. 2005. Investigation of erythromycin and tetracycline resistance genes in methicillin-resistant staphylococci. Int. J. Antimicrob. Agents. 26: 213-218.
4. Azap O.K., H. Arslan, F. Timurkaynak, G. Yapar, E. Oruc and U. Gagir. 2005. Incidence of inducible clindamycin resistance in staphylococci: first results from Turkey. Clin. Microbiol. Infect. 11:582-584.
5. Chavez-Bueno S., B. Bozdogan, K. Katz, K.L. Bowlware, N. Cushion, D. Cavuoti, N. Ahmad,G.H. Jr McCracken and P.C. Appelbaum. 2005. Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas. Antimicrob. Agents. Chemother. 49: 2283-2288.
6. CLSI. 2006. Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standards, 9th ed. Clinical and Laboratory Standards Institute, Wayne, PA.
7. Delialioglu N., G. Aslan, C. Ozturk, V. Baki, S. Sen and G. Emekdas. 2005. Inducible clindamycin resistance in staphylococci isolated from clinical samples. Jpn. J. Infect. Dis. 58: 104-106.
8. Deresinski S. 2005. Methicillin-resistant Staphylococcus aureus: an evolutionary, epidemiologic, and therapeutic odyssey. Clin. Infect. Dis. 40: 562-573.
9. Fokas S., S. Fokas, M. Tsironi, M. Kalkani and M. Dionysopouloy. 2005. Prevalence of inducible clindamycin resistance in macrolide-resistant Staphylococcus spp. Clin. Microbiol. Infect. 11: 337-340.
10. Gadepalli R., B. Dhawan, S. Mohanty, A. Kapil, B.K. Das and H. Chaudhry. 2006. Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus. Indian J. Med. Res. 123: 571-573.
11. Garza-Ramos G., L. Xiong, P. Zhong and A. Mankin. 2001. Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA. J. Bacteriol. 183: 6898-6907.
12. Harms J.M., F. Schlünzen, P. Fucini, H. Bartels and A. Yonath. 2004. Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. B.M.C. Biol. 2: 4.
13. Janapatla R.P., J.J. Yan, A.H. Huang, H.M. Chen, H.M. Wu and J.J. Wu. 2007. Inducible clindamycin resistance in Staphylococcus aureus isolates causing bacteremia at a university hospital in southern Taiwan. Diagn. Microbiol. Infect. Dis. 58: 203-209.
14. Karadenizli A. 2002. Hastanelerde metisilin dirençli Staphylococcus aureus (MRSA) control politikalarý ve MRSA. (in Turkish). Hastane Ýnfeksiyonlarý Dergisi 6: 12-18
15. Khan S.A., M.S. Nawaz, A.A. Khan and C.E. Cerniglia. 1999. Simultaneous detection of erythromycin-resistant methylase genes ermA and ermC from Staphylococcus spp. By multiplex-PCR. Mol. Cell. Probes 13: 381-387.
16. Kilic A., H. Li, C.W. Stratton and Y.W. Tang. 2006. Antimicrobial susceptibility patterns and staphylococcal cassette chromosome mec types of, as well as Panton-Valentine leukocidin occurrence among, methicillin-resistant Staphylococcus aureus isolates from children and adults in middle Tennessee. J. Clin. Microbiol. 44: 4436-4440.
17. Kilic A., T. Demiray, M.A. Saracli, G. Bahar, H. Aydogan, M. Baysallar and L Doganci. 2004. Bacteriological characterization of vancomycin-resistant enterococci in a pediatric hospital in Turkey. Ann. Microbiol. 54: 543-551.
18. Layer F., B. Ghebremedhin, W. König and B. König. 2006. Heterogeneity of methicillin susceptible Staphylococcus aureus strains at a German University Hospital implicates the circulating-strain pool as a potential source of emerging methicillin-resistant S. aureus clones. J. Clin. Microbiol. 44: 2179-2185.
19. Leclercq R. 2002. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin. Infect. Dis. 34: 482-492.
20. Leclercq R. and P. Courvalin. 1991. Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification. Antimicrob. Agents Chemother. 35: 1267-72.
21. Lim J.A., A.R. Kwon, S.K. Kim, V. Chong, K. Lee and E.C. Choi. 2002. Prevalence of resistance to macrolide, lincosamide and streptogramin antibiotics in Gram-positive cocci isolated in a Korean hospital. J. Antimicrob. Chemother. 49: 489-495.
22. Lina G., A. Quaglia, M.E. Reverdy, R. Leclercq, F. Vandenesch and J. Etiennc. 1999. Distribution of genes encoding resistance to macrolides, lincosamides, and streptogramins among staphylococci. Antimicrob. Agents Chemother. 43: 1062-1066.
23. Manian F.A., P.L.Meyer, J. Setzer and D. Senke. 2003. Surgical site infections associated with methicillin-resistant Staphylococcus aureus: do postoperative factors play a role? Clin. Infect. Dis. 36: 863-868.
24. Martineau F., F.J. Picard, N. Lansac, C. Ménard, P.H. Roy, M. Ouellette and M.G. Bergeronl. 2000. Correlation between the resistance genotype determined by multiplex PCR assays and the antibiotic susceptibility patterns of Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob. Agents Chemother. 44: 231-238.
25. Otsuka T., H. Zaraket, T. Takano, K. Saito, S. Dohmae, W. Higuchi and T. Yamamoto. 2007. Macrolide-lincosamide-streptogramin B resistance phenotypes and genotypes among Staphylococcus aureus clinical isolates in Japan. Clin. Microbiol. Infect. 13: 325-327.
26. Oztop A.Y., H. Pinarbasi, S. Kocagoz, M.Z. Bakici and M. Bakir. 2004. Molecular genotyping of methicillin-resistant Staphylococcus aureus strains in a teaching hospital in Turkey. Microb. Drug Resist. 10: 154-159.
27. Park J.Y., J.S. Jin, H.Y. Kang, E.H. Jeong, J.C. Lee, Y.C. Lee, S.Y. Seol, D.T. Cho and J. Kim. 2007. A comparison of adult and pediatric methicillin-resistant Staphylococcus aureus isolates collected from patients at a University Hospital in Korea. J. Microbiol. 45: 447-452.
28. Robinson D.A. and M.C. Enright. 2003. Evolutionary models of the emergence of methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 47: 3926-3934.
29. Schmitz F.J., J. Verhoef and A.C. Fluit. 1999. Prevalence of resistance to MLS antibiotics in 20 European university hospitals participating in the European SENTRY surveillance programme. Sentry Participants Group. J. Antimicrob. Chemother. 43: 783-792.
30. Schmitz F.J., R. Sadurski, A. Kray, M. Boos, R. Geisel, K. Köhrer, J. Verhoef and A.C. Fluit. 2000. Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. J. Antimicrob. Chemother. 45: 891-894.
31. Schreckenberger P.C., E. Ilendo and K.L. Ristow. 2004. Incidence of constitutive and inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci in a community and a tertiary care hospital. J. Clin. Microbiol. 42: 2777-2779.
32. Sekiguchi J., T. Fujino, K. Saruta, F. Kawano, J. Takami, H. Miyazaki, T Kuratsuji, H. Yoshikura and T. Kirikae. 2003. Spread of erythromycin-, tetracycline- and aminoglycoside-resistant genes in methicillin-resistant Staphylococcus aureus clinical isolates in a Kumamoto Hospital. Jpn. J. Infect. Dis. 56: 133-137.
33. Seybold U., E.V. Kourbatova, J.G. Johnson, S.J. Halvosa, Y.F. Wang, M.D. King, S.M. Ray and H.M. Blumberg. 2006. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA300 genotype as a major cause of health care-associated blood stream infections. Clin. Infect. Dis. 42: 647-656.
34. Spiliopoulou I., E. Petinaki, P. Papandreou and G. Dimitracopoulos. 2004. erm(C) is the predominant genetic determinant for the expression of resistance to macrolides among methicillin-resistant Staphylococcus aureus clinical isolates in Greece. J. Antimicrob. Chemother. 53: 814-817.
35. Strommenger B., C. Kettlitz, G. Werner and W. Witte. 2003. Multiplex PCR assay for simultaneous detection of nine clinically relevant antibiotic resistance genes in Staphylococcus aureus. J. Clin. Microbiol. 41: 4089-4094.
36. Volokbov D., V. Chizhikov, K. Chumakov and A. Rasooly. 2003. Microarray analysis of erythromycin resistance determinants. J. Appl. Microbiol. 95: 787-798.
37. Yilmaz G., K. Aydin, S. Iskender, R. Caylan and I. Koksal. 2007. Detection and prevalence of inducible clindamycin resistance in staphylococci. J. Med. Microbiol. 56: 342-345.