Effect of berberine on fructose-induced insulin resistance and expression of tumor necrosis factor-alpha in liver of rats

Chinese Pharmacological Bulletin

Volumn 24, Issue 11, 2008, Pages 1479-1482

  Gao, Zhi Qing ^a   Leng, San Hua ^a   Lu, Fu Er ^a   Xie, Mei Juan ^a   Xu, Li Jun ^a   Wang, Kai Fu ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Berberine; High fructose FFA; Insulin resistance; TNF

Indexed keywords

BERBERINE; CARBOXYMETHYLCELLULOSE; CHOLESTEROL; DRUG VEHICLE; FATTY ACID; FRUCTOSE; GLUCOSE; INSULIN; METFORMIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIVER; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 60749110187     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Hsieh P S. Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats [J]. J Hyperten, 2005, 23 (12): 2209-17.
2. Mehdi H, Mohsen A, Manoochehr M. Effect of vanadyl sulfate on fructose-induced insulin resistance rat[J]. Iran Biomed J, 2003, 7 (4): 179-82.
3. Wen J S, Hu B, Long G, ey al. Effects of rosiglitazone on blood glucose, blood lipid and vascular remodeling in rats fed with high fructose diet[J]. Chin Pharmacol Bull, 2004, 20(5): 571-5.
4. Olatunji L A, Soladoye A O. Increased magnesium intake prevents hyperlipidemia and insulin resistance and reduces lipid peroxidation in fructose-fed rats[J]. Pathophysiology, 2007, 14: 11-5.
5. Suganthi R, Rajamani S, Ravichandran M K, et al. Effect of food seasoning spices mixture on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats [J]. J Med Food, 2007, 10: 149-53.
6. Lin H J, Loh C H, Liao M T, et al. Attenuation of hypertriglyceridemia-induced pressor effect in rats with fructose-induced insulin resistance[J]. Chin J Physiol, 2007, 50: 16-21.
7. He B C, Kang Q, Yang J Q, et al. Correlation between antitumor activity of berberine and the inhibition of Wnt/β-catenin signal pathway[J]. Chin Pharmacol Bull, 2005, 21(9): 1108-11.
8. Lin J P, Yang J S, Lee J H, et al. Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line [J]. World J Gastroenterol, 2006, 12(1): 21-8.
9. Wang C B, Lu F E, Leng S H, et al. Effects of berberine on the activity of glucokinase and the gene expression in cultured hepG2 cells[J]. Chin Pharmacol Bull, 2007, 23(9): 1145-7.
10. Xin H W, Wu X C, Li Q, et al. Study on differential expression of genes associated with metabolism by cDNA microarry in rat liver treated with berberine chloride[J]. Chin Pharmacal Bull, 2004, 20 (10): 1122-6.
11. Ouyang L Z, Lu F E, Liu W J, et al. Effect of berberine on the expression of glucokinase and glucokinase regulatory protein in insulin-resistant rats[J]. Shijie Huaren Xiaohua Zazhi, 2007, 15 (8): 885-9.
12. Togashi N, Ura N, Higashiura K, et al. Effect of TNF-alpha converting enzyme inhibitor on insulin resistance in fructose-fed rats[J]. Hypertention, 2002, 39: 578-80.
13. Leng S H, Lu F E, Xu L J. Therapeutic effects of. berberine in impaired glucose tolerance rats and its. influence on insulin secretion [J]. Acta Pharmacal Sin, 2004, 25(4): 496-502.
14. Yang J, Wang H D, Lu D X, et al. Effects of neutral sulfate berberine on LPS-induced cardiomyocyte TNF-alpha secretion, abnormal calcium cycling, and cardiac dysfunction[J]. Acta Pharmacol Sin, 2006, 27(2): 173-8.