Highly efficient, selective and sensitive molecular screening of acetylcholinesterase inhibitors of natural origin by solid-phase extraction-liquid chromatography/electrospray ionisation-octopole-orthogonal acceleration time-of-flight-mass spectrometry and novel thin-layer chromatography-based bioautography

Journal of Chromatography A

Volumn 1216, Issue 12, 2009, Pages 2519-2528

  Mroczek, Tomasz ^a  

^a Department of Pharmacognosy with Medicinal Plant Laboratory Unit ^*  (Poland)

Author keywords

Acetylcholinesterase inhibitors; Amaryllidaceae alkaloids; Bioauthography; High performance liquid chromatography; Time of flight mass spectrometry

Indexed keywords

ACETYLCHOLINESTERASE INHIBITORS; AMARYLLIDACEAE ALKALOIDS; ATLANTIS; BIOAUTHOGRAPHY; BIOAUTOGRAPHY; ELECTROSPRAY; GALANTHAMINE; HIGH SENSITIVITIES; IONISATION; LIMIT OF DETECTIONS; MASS ACCURACIES; ORTHOGONAL ACCELERATIONS; PLANT MATERIALS; PRESSURIZED LIQUID EXTRACTIONS; SELECTIVE SOLID-PHASE EXTRACTIONS; SIGNAL TO NOISE; SOLID-PHASE EXTRACTIONS; STATIONARY PHASE; THIN-LAYER CHROMATOGRAPHIES; TIME-OF-FLIGHT MASS SPECTROMETRY;

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; NEGATIVE IONS; SILICA; SOLVENT EXTRACTION; SPECTRUM ANALYSIS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1,2 DIHYDROGALANTHAMINE; CHOLINESTERASE INHIBITOR; GALANTAMINE; NARCISSUS JONQUILLA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; DENSITOMETRY; ELECTROSPRAY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; NONHUMAN; PRIORITY JOURNAL; SCREENING; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION; THIN LAYER CHROMATOGRAPHY; TIME OF FLIGHT MASS SPECTROMETRY;

AMARYLLIDACEAE ALKALOIDS; CHOLINESTERASE INHIBITORS; CHROMATOGRAPHY, LIQUID; CHROMATOGRAPHY, THIN LAYER; CRINUM; DENSITOMETRY; GALANTHUS; MASS SPECTROMETRY; NARCISSUS; PLANT EXTRACTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION;

AMARYLLIDACEAE; NARCISSUS JONQUILLA;

EID: 60649103834     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.01.061     Document Type: Article

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