Association of the polymorphisms of sodium transport related genes with essential hypertension

Chinese Journal of Medical Genetics

Volumn 26, Issue 1, 2009, Pages 91-94

  Gong, Ping Yuan ^a   Shen, Guo Min ^a   Peng, He Mei ^b   Luo, Yan ^a   Shen, Yan ^a   Zhao, Xiao ^a  

^a HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Luotong Hospital   (China)

Author keywords

adducin gene; Essential hypertension; Na+ K + ATPase 2; Sodium transport

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA ADDUCIN; CHLORINE; POTASSIUM; SODIUM;

ARTICLE; BODY MASS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ESSENTIAL HYPERTENSION; GENE FREQUENCY; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; POPULATION; POTASSIUM BLOOD LEVEL; SODIUM BLOOD LEVEL; SODIUM TRANSPORT; SYSTOLIC BLOOD PRESSURE;

CALMODULIN-BINDING PROTEINS; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERTENSION; ION TRANSPORT; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 60549114177     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1003-9406.2009.01.021     Document Type: Article

References (15)

1. Katsuya T, Ishikawa K, Sugimoto K, et al. Salt sensitivity of Japanese from the viewpoint of gene polymorphism. Hypertens Res, 2003, 26: 521-525.
2. Glorioso N, Filigheddu F, Cusi D, et al. Alpha-Adducin 460Trp allele is associated with erythrocyte Na transport rate in north Sardinian primary hypertensives. Hypertension, 2002, 39: 357-362.
3. Zhang J, Lee MY, Cavalli M, et al. Sodium pump alpha 2 subunits control myogenic tone and blood pressure in mice. J Physiol, 2005, 569: 243-256.
4. Shin MH, Chung EK, Kim HN, et al. Alpha-adducin Gly460Trp polymorphism and essential hypertension in Korea. J Korean Med Sci, 2004, 19: 812-814.
5. Melander O, Bengtsson K, Orho-Melander M, et al. Role of the Gly460Trp polymorphism of the alpha-adducin gene in primary hypertension in Scandinavians. J Hum Hypertens, 2000, 14: 43-46.
6. Narita I, Goto S, Saito N, et al. Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patients. Hypertension, 2003, 42: 304-309.
7. Tiago AD, Nkeh B, Candy GP, et al. Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry. Cardiovasc J S Afr, 2001, 12: 75-80.
8. Wang WY, Adams DJ, Glenn CL, et al. The Gly460Trp variant of alpha-adducin is not associated with hypertension in white Anglo-Australians. Am J Hypertens, 1999, 12: 632-636.
9. Hou R, Liu ZQ, Xue MZ, et al. Is Gly460Trp variant of alpha-adducin associated with essential hypertension in the Hans of Chinese population. Chin J Med Genet, 2000, 17: 413-416.
10. Qian YS, Zhang Y, Zhang WZ. Relationship between the polymorphism of alpha-adducin gene and the two phenotypes of constitutions in patients with essential hypertension classified by TCM. Chin J Integrat Med, 2006, 26: 698-701.
11. Hu BC, Chu SL, Wang JG, et al. Single nucleotide polymorphisms of three candidate genes in essential hypertension. Chin J Intern Med, 2006, 45: 281-284.
12. Richart T, Thijs L, Kuznetsova T, et al. Intra-erythrocyte cation concentrations in relation to the C1797T beta-adducin polymorphism in a general population. J Hum Hypertens, 2007, 21: 387-392.
13. Zhang ZX, Liu Y, Lin RY, et al. Connection between ADD1 gene Gly460Trp polymorphism and essential hypertension from Xinjiang Kazakhs. Fudan Univ (J Med Sci), 2005, 32: 239-242.
14. Wang C, Sun G, Yan XL, et al. Study of cradducin and endothel ial nitric oxide synthase gene polymorphism in patients with essential hypertension in Mongulia population. J Clin Cardiol, 2007, 23: 525-527.
15. Dou XF, Sun K, Huang XH, et al. α-Adducin and angiotensin converting enzyme polymorphisms in essential hypertension. Chin Cir J, 2004, 19: 286-289.