Is Gly460Trp variant of α-adducin associated with essential hypertension in the Hans of Chinese population

Chinese Journal of Medical Genetics

Volumn 17, Issue 6, 2000, Pages 413-416

  Hou, R ^a   Liu, Z ^a   Xue, M ^a   Wang, Y ^a   Ye, T ^a   Sun, C ^a   Wang, Z ^a   Liu, Y ^a  

^a XI'AN MEDICAL UNIVERSITY   (China)

Author keywords

adducin; Essential hypertension; Gene; Variant

Indexed keywords

ADDUCIN; GLYCINE; PROTEIN SUBUNIT; TRYPTOPHAN;

AGE; AMINO ACID SUBSTITUTION; ARTICLE; BLOOD PRESSURE; BODY MASS; CHINESE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA SEQUENCE; ESSENTIAL HYPERTENSION; EXON; GENE FREQUENCY; GENE ISOLATION; GENETIC ANALYSIS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROTEIN VARIANT; SINGLE STRAND CONFORMATION POLYMORPHISM;

ADULT; CALMODULIN-BINDING PROTEINS; CHINA; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PROTEIN SUBUNITS; VARIATION (GENETICS);

EID: 0034489309     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Primary structure and domain organization of human alpha and beta adducin
2. Adducin regulation
3. Association of the α-adducin locus with essential hypertension
4. Polymorphisms of α-adducin and salt sensitivity in patients with essential hypertension
5. Polymorphisms of α-adducin and hypertension
6. Lack of association between the α-adducin locus and essential hypertension in the Japanese population
7. Human α-adducin gene, blood pressure, and sodium metabolism
8. Genetic association of salt sensitive hypertension with polymorphism of short tandem sequence in human chromosome; 16p β ENaCGT-1
9. Two point mutation within the adducin genes are involved in blood pressure variation
10. Hypertension-associated point mutations in the adducin α and β subunits affect actin cytoskeleton and ion transport
11. Genomic organization of the human α-adducin gene and its alternately spliced isoforms