Noninvasive functional imaging of P-glycoprotein-mediated doxorubicin resistance in a mouse model of hereditary breast cancer to predict response, and assign P-gp inhibitor sensitivity

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 36, Issue 3, 2009, Pages 406-412

  Van Leeuwen, Fijs W B ^a   Buckle, Tessa ^a   Kersbergen, Ariena ^a   Rottenberg, Sven ^a   Gilhuijs, Kenneth G A ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

Author keywords

99mTc MIBI; Computer aided diagnosis; Mouse tumor models; Multidrug resistance; P glycoprotein

Indexed keywords

BRCA1 PROTEIN; DOXORUBICIN; GLYCOPROTEIN P INHIBITOR; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER MODEL; CANCER RESISTANCE; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GENE EXPRESSION; MOUSE; NONHUMAN; ONCOGENE; PREDICTION; SCINTILLATION CAMERA;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION; GENES, BRCA1; GENES, P53; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; P-GLYCOPROTEIN; P-GLYCOPROTEINS; RADIONUCLIDE IMAGING; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI;

EID: 60549108554     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-1010-z     Document Type: Article

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