Human microbiota-secreted factors inhibit shiga toxin synthesis by enterohemorrhagic escherichia coli O157:H7

Infection and Immunity

Volumn 77, Issue 2, 2009, Pages 783-790

  De Sablet, Thibaut ^a,b   Chassard, Christophe ^a,c   Bernalier Donadille, Annick ^a   Vareille, Marjolaine ^a   Gobert, Alain P ^a   Martin, Christine ^a  

^a CEMAGREF   (France)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOINDUCER 3; MESSENGER RNA; PROTEIN QSEA; PROTEIN QSEC; PROTEIN SDIA; RECA PROTEIN; SHIGA TOXIN; UNCLASSIFIED DRUG; VEROTOXIN 2; VIRULENCE FACTOR;

ADULT; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTEROIDES THETAIOTAOMICRON; CECUM; CHILD; COMMENSAL ESCHERICHIA COLI; CONTROLLED STUDY; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ESCHERICHIA COLI O157; FEMALE; GENE EXPRESSION; GENE REPRESSION; HUMAN; MALE; MOLECULAR WEIGHT; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROKARYOTE; QUORUM SENSING; RAT; STX2 GENE; TOXIN SYNTHESIS; ADOLESCENT; ANIMAL; BACTEROIDES; BIOSYNTHESIS; DNA REPAIR; DOWN REGULATION; DRUG ANTAGONISM; FECES; FISCHER 344 RAT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; STOMACH JUICE; VIRULENCE;

ADOLESCENT; ADULT; ANIMALS; BACTEROIDES; CECUM; CHILD; CHILD, PRESCHOOL; DOWN-REGULATION; ESCHERICHIA COLI O157; FECES; FEMALE; GASTROINTESTINAL CONTENTS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MALE; QUORUM SENSING; RATS; RATS, INBRED F344; SHIGA TOXIN 2; SOS RESPONSE (GENETICS); TRANSCRIPTION, GENETIC; VIRULENCE; YOUNG ADULT;

EID: 60549105559     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01048-08     Document Type: Article

References (38)

1. Asahara, T., K. Shimizu, K. Nomoto, T. Hamabata, A. Ozawa, and Y. Takeda. 2004. Probiotic bifidobacteria protect mice from lethal infection with Shiga toxin-producing Escherichia coli 0157:H7. Infect. Immun. 72: 2240-2247.
2. Bansal, T., D. Englert, J. Lee, M. Hegde, T. K. Wood, and A. Jayaraman. 2007. Differential effects of epinephrine, norepinephrine, and indole on Escherichia coli OI57:H7 chemotaxis. colonization, and gene expression. Infect. Immun. 75:4597-4607.
3. Boerlin, P., S. A. McEwen, F. Boerlin-Petzold, J. B. Wilson, R. P. Johnson, and C. L. Gyles. 1999. Associations between virulence factors of Shiga toxin-producing Escherichia coli and disease in humans. J. Clin. Microbiol. 37:497-503.
4. Carey, C. M., M. Kostrzynska, S. Ojha, and S. Thompson. 2008. The effect of probiotics and organic acids on Shiga toxin 2 gene expression in entero-hemorrhagic Escherichia coli 0157:H7. J. Microbiol. Methods 73:125-132.
5. Chassard, C, V. Goumy, M. Leclerc, C. Del'homme, and A. Bernalier-Donadille. 2007. Characterization of the xylan-degrading microbial community from human faeces. FEMS Microbiol. Ecol. 61:121-131.
6. Clarke, M. B., D. T. Hughes, C. Zhu, E. C. Boedeker, and V. Sperandio. 2006. The QseC sensor kinase: a bacterial adrenergic receptor. Proc. Natl. Acad. Sci. USA 103:10420-10425.
7. Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PGR products. Proc. Nad. Acad. Sci. USA 97:6640-6645.
8. Dean-Nystrom, E. A., A. K. Melton-Celsa, J. F. Pohlenz, H. W. Moon, and A. D. O'Brien. 2003. Comparative pathogenicity of Escherichia coli 0157 and intimin-negative non-0157 Shiga toxin-producing E coli strains in neonatal pigs. Infect. Immun. 71:6526-6533.
9. 2 variants in Shiga toxin-producing Escherichia coli belonging to seropathotypes A and C. Microbiology 254:176-186.
10. Dowd, S. E. 2007. Escherichia coli 0157:H7 gene expression in the presence of catecholamine norepinephrine. FEMS Microbiol. Lett. 273:214-223.
11. Eckburg, P. B., E. M. Bik, C. N. Bernstein, E. Purdom, L. Dethlefsen, M. Sargent, S. R. Gill, K. E. Nelson, and D. A. Relman. 2005. Diversity of the human intestinal microbial flora. Science 308:1635-1638.
12. Gamage, S. D., A. K. Patton, J. E. Strasser, C. L. Chalk, and A. A. Weiss. 2006. Commensal bacteria influence Escherichia coli 0157:H7 persistence and Shiga toxin production in the mouse intestine. Infect. Immun. 74:1977-1983.
13. Gamage, S. D., J. E. Strasser, C. L. Chalk, and A. A. Weiss. 2003. Nonpathogenic Escherichia coli can contribute to the production of Shiga toxin. Infect. Immun. 71:3107-3115.
14. Hold, G. L., S. E. Pryde, V. J. Russell, E. Furrie, and H. J. Flint. 2002. Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis. FEMS Microbiol. Ecol. 39:33-39.
15. Hooper, L. V., M. H. Wong, A. Thelin, L. Hansson, P. G. Falk, and J. I. Gordon. 2001. Molecular analysis of commensal host-microbial relationships in the intestine. Science 291:881-884.
16. Hungate, R. E. 1969. A roll-tube method for the cultivation of strict anaerobes, p. 117-132. In D. W. G. J. R. Norris (ed.). Methods in microbiology. Academic Press, New York, NY.
17. Jeon, B., and K. Itoh. 2007. Production of shiga toxin by a luxS mutant of Escherichia coli O157:H7 in vivo and in vitro. Microbiol. Immunol. 51:391- 396.
18. Kelly, D., J. I. Campbell, T. P. King, G. Grant, E. A. Jansson, A. G. Coutts, S. Pettersson, and S, Conway. 2004. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat. Immunol. 5:104-112.
19. Kendall, M. M., D. A. Rasko, and V. Sperandio. 2007. Global effects of the cell-to-cell signaling molecules autoinducer-2, autoinducer-3, and epinephrine in a luxS mutant of enterohemorrhagic Escherichia coli. Infect. Immun. 75:4875-4884.
20. Lan, A., A. Bruneau, C. Philippe, V. Rochet, A. Rouault, C. Herve, N. Roland, S. Rabot, and G. Jan. 2007. Survival and metabolic activity of selected strains of Propionibacterium freudenreichii in the gastrointestinal tract of human microbiota-associated rats. Br. J. Nutr. 97:714-724.
21. Lee, J., A. Jayaraman, and T. K. Wood. 2007. Indole is an inter-species biofilm signal mediated bv SdiA. BMC Microbiol. 7:42. doi:10.1186/1471-2180-7-42.
22. Leedle, J. A., and R. B. Hespell. 1980. Differential carbohydrate media and anaerobic replica plating techniques in delineating carbohydrate-utilizing subgroups in rumen bacterial populations. Appl. Environ. Microbiol. 39:709- 719.
23. Liévin-Le Moal, V., and A. L. Servin. 2006. The front line of enteric host defense against unwelcome intrusion of harmful microorganisms: mucins, antimicrobial peptides, and microbiota. Clin. Microbiol. Rev. 19:315-337.
24. Livny, J., and D. I. Friedman. 2004. Characterizing spontaneous induction of Stx encoding phages using a selectable reporter system. Mol. Microbiol. 51:1691-1704.
25. Medellin-Peña, M. J., H. Wang, R. Johnson, S. Anand, and M. W. Griffiths. 2007. Probiotics affect virulence-related gene expression in Escherichia coli O157:H7. Appl. Environ. Microbiol. 73:4259-4267.
26. Momose, Y., K. Hirayama, and K. Itoh. 2007. Effect of organic acids on inhibition of Escherichia coli 0157:H7 colonization in gnotobiotic mice associated with infant intestinal microbiota. Antonie van Leeuwenhoek 93: 141-149.
27. Mundy, R., F. Girard, A. J. FitzGerald, and G. Frankel. 2006. Comparison of colonization dynamics and pathology of mice infected with enteropatho-genic Escherichia coli. enterohaemorrhagic E. coli and Citrobacter rodentium. FEMS Microbiol. Lett. 265:126-132.
28. Naylor, S. W., D. L. Gaily, and J. C. Low. 2005. Enterohaemorrhagic E. coli in veterinary medicine. Int. J. Med. Microbiol. 295:419-441.
29. Ritchie, J. M., P. L. Wagner, D. W. Acheson, and M. K. Waldor. 2003. Comparison of Shiga toxin production by hemolytic-uremic syndrome-associated and bovine-associated Shiga toxin-producing Escherichia coli isolates. Appl. Environ. Microbiol. 69:1059-1066.
30. Robinson, C. M., J. F. Sinclair, M. J. Smith, and A. D. O'Brien. 2006. Shiga toxin of enterohemorrhagic Escherichia coli type O157:H7 promotes intestinal colonization. Proc. Natl. Acad. Sci. USA 103:9667-9672.
31. Salyers, A. A., J. R. Vercellotti, S. E. West, and T. D. Wilkins. 1977. Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon. Appl. Environ. Microbiol. 33:319-322.
32. Sperandio, V., J. L. Mellies, W. Nguyen, S. Shin, and J. B. Kaper. 1999. Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc. Natl. Acad. Sci. USA 96: 15196-15201.
33. Sperandio, V., A. G. Torres, J. A. Giron, and J. B. Kaper. 2001. Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J. Bacteriol. 183:5187-5197.
34. Sperandio, V., A. G. Torres, B. Jarvis, J. P. Nataro, and J. B. Kaper. 2003. Bacteria-host communication: the language of hormones. Proc. Natl. Acad. Sci. USA 100:8951-8956.
35. Teng, L. J., P. R Hsueh, Y. H. Huang, and J. C. Tsai. 2004. Identification of Bacteroides thetaiotaomicron on the basis of an unexpected specific amplicon of universal 16S ribosomal DNA PCR. J. Clin. Microbiol. 42:1727-1730.
36. Toshima, H., A. Yoshimura, K. Arikawa, A. Hidaka, J. Ogasawara, A. Hase, H. Masaki, and Y. Nishikawa. 2007. Enhancement of Shiga toxin production in enterohemorrhagic Escherichia coli serotype O157:H7 by DNase colicins. Appl. Environ. Microbiol. 73:7582-7588.
37. Wagner, P. L., M. N. Neely, X. Zhang, D. W. Acheson, M. K. Waldor, and D. I. Friedman. 2001. Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain. J. Bacteriol. 183:2081-2085.
38. Zoetendal, E. G., E. E. Vaughan, and W. M. de Vos. 2006. A microbial world within us. Mol. Microbiol. 59:1639-1650.