-
1
-
-
21744450786
-
Heparan sulphate proteoglycans: The sweet side of development
-
Hacker U, Nybakken K, Perrimon N (2005) Heparan sulphate proteoglycans: The sweet side of development. Nat Rev Mol Cell Biol 6:530-541.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 530-541
-
-
Hacker, U.1
Nybakken, K.2
Perrimon, N.3
-
2
-
-
21744431575
-
The sweet and sour of cancer: Glycans as novel therapeutic targets
-
Fuster MM, Esko JD (2005) The sweet and sour of cancer: Glycans as novel therapeutic targets. Nat Rev Cancer 5:526-542.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 526-542
-
-
Fuster, M.M.1
Esko, J.D.2
-
3
-
-
0033057962
-
Mammalian heparanase: Gene cloning, expression, and function in tumor progression and metastasis
-
Vlodavsky I, et al. (1999) Mammalian heparanase: Gene cloning, expression, and function in tumor progression and metastasis. Nat Med 5:793-802.
-
(1999)
Nat Med
, vol.5
, pp. 793-802
-
-
Vlodavsky, I.1
-
4
-
-
0033028789
-
Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis
-
Hulett MD, et al. (1999) Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat Med 5:803-809.
-
(1999)
Nat Med
, vol.5
, pp. 803-809
-
-
Hulett, M.D.1
-
5
-
-
0034904048
-
Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis
-
Vlodavsky I, Friedmann Y (2001) Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. J Clin Invest 108:341-347.
-
(2001)
J Clin Invest
, vol.108
, pp. 341-347
-
-
Vlodavsky, I.1
Friedmann, Y.2
-
6
-
-
33748683743
-
Regulation, function, and clinical significance of heparanase in cancer metastasis and angiogenesis
-
Ilan N, Elkin M, Vlodavsky I (2006) Regulation, function, and clinical significance of heparanase in cancer metastasis and angiogenesis. Int J Biochem Cell Biol 38:2018-2039.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 2018-2039
-
-
Ilan, N.1
Elkin, M.2
Vlodavsky, I.3
-
7
-
-
34547313009
-
Mammalian heparanase: What is the message?
-
Vreys V, David G (2007) Mammalian heparanase: What is the message? J Cell Mol Med 11:427-452.
-
(2007)
J Cell Mol Med
, vol.11
, pp. 427-452
-
-
Vreys, V.1
David, G.2
-
8
-
-
0037162555
-
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis
-
Goldshmidt O, et al. (2002) Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis. Proc Natl Acad Sci USA 99:10031-10036.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10031-10036
-
-
Goldshmidt, O.1
-
11
-
-
36048945359
-
Heparanase levels are elevated in the plasma of pediatric cancer patients and correlate with response to anticancer treatment
-
Shafat I, et al. (2007) Heparanase levels are elevated in the plasma of pediatric cancer patients and correlate with response to anticancer treatment. Neoplasia 9:909-916.
-
(2007)
Neoplasia
, vol.9
, pp. 909-916
-
-
Shafat, I.1
-
12
-
-
33846280793
-
Cloning, expression, and characterization of an alternatively spliced variant of human heparanase
-
Nasser NJ, Avivi A, Shusy M, Vlodavsky I, Nevo E (2007) Cloning, expression, and characterization of an alternatively spliced variant of human heparanase. Biochem Biophys Res Commun 354:33-38.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 33-38
-
-
Nasser, N.J.1
Avivi, A.2
Shusy, M.3
Vlodavsky, I.4
Nevo, E.5
-
13
-
-
27244454165
-
Adaptive evolution of heparanase in hypoxia-tolerant Spalax: Gene cloning and identification of a unique splice variant
-
Nasser NJ, et al. (2005) Adaptive evolution of heparanase in hypoxia-tolerant Spalax: Gene cloning and identification of a unique splice variant. Proc Natl Acad Sci USA 102:15161-15166.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15161-15166
-
-
Nasser, N.J.1
-
16
-
-
27644542151
-
Oxygen and carbon dioxide fluctuations in burrows of subterranean blind mole rats indicate tolerance to hypoxic-hypercapnic stresses
-
Shams I, Avivi A, Nevo E (2005) Oxygen and carbon dioxide fluctuations in burrows of subterranean blind mole rats indicate tolerance to hypoxic-hypercapnic stresses. Comp Biochem Physiol A Mol Integr Physiol 142:376-382.
-
(2005)
Comp Biochem Physiol A Mol Integr Physiol
, vol.142
, pp. 376-382
-
-
Shams, I.1
Avivi, A.2
Nevo, E.3
-
17
-
-
0026048295
-
Hypoxic survival differs between two mole rat species (Spalax ehrenbergi) of humid and arid habitats
-
Arieli R, Nevo E (1991) Hypoxic survival differs between two mole rat species (Spalax ehrenbergi) of humid and arid habitats. Comp Biochem Physiol A 100:543-545.
-
(1991)
Comp Biochem Physiol A
, vol.100
, pp. 543-545
-
-
Arieli, R.1
Nevo, E.2
-
18
-
-
0031043096
-
Working underground: Respiratory adaptations in the blind mole rat
-
Widmer HR, Hoppeler H, Nevo E, Taylor CR, Weibel ER (1997) Working underground: Respiratory adaptations in the blind mole rat. Proc Natl Acad Sci USA 94:2062-2067.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2062-2067
-
-
Widmer, H.R.1
Hoppeler, H.2
Nevo, E.3
Taylor, C.R.4
Weibel, E.R.5
-
19
-
-
23444460824
-
Increased blood vessel density provides the mole rat physiological tolerance to its hypoxic subterranean habitat
-
Avivi A, et al. (2005) Increased blood vessel density provides the mole rat physiological tolerance to its hypoxic subterranean habitat. FASEB J 19:1314-1316.
-
(2005)
FASEB J
, vol.19
, pp. 1314-1316
-
-
Avivi, A.1
-
20
-
-
4344663507
-
Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation
-
Ashur-Fabian O, et al. (2004) Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation. Proc Natl Acad Sci USA 101:12236-12241.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 12236-12241
-
-
Ashur-Fabian, O.1
-
21
-
-
25444490700
-
p53, a key player in tumoral and evolutionary adaptation: A lesson from the Israeli blind subterranean mole rat
-
Avivi A, Ashur-Fabian O, Amariglio N, Nevo E, Rechavi G (2005) p53, a key player in tumoral and evolutionary adaptation: A lesson from the Israeli blind subterranean mole rat. Cell Cycle 4:368-372.
-
(2005)
Cell Cycle
, vol.4
, pp. 368-372
-
-
Avivi, A.1
Ashur-Fabian, O.2
Amariglio, N.3
Nevo, E.4
Rechavi, G.5
-
22
-
-
20144376911
-
Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase
-
Levy-Adam F, et al. (2005) Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase. J Biol Chem 280:20457-20466.
-
(2005)
J Biol Chem
, vol.280
, pp. 20457-20466
-
-
Levy-Adam, F.1
-
23
-
-
0020640516
-
Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: Relationship to tumor cell metastasis
-
Vlodavsky I, Fuks Z, Bar-Ner M, Ariav Y, Schirrmacher V (1983) Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: Relationship to tumor cell metastasis. Cancer Res 43:2704-2711.
-
(1983)
Cancer Res
, vol.43
, pp. 2704-2711
-
-
Vlodavsky, I.1
Fuks, Z.2
Bar-Ner, M.3
Ariav, Y.4
Schirrmacher, V.5
-
24
-
-
4344598247
-
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis
-
Edovitsky E, Elkin M, Zcharia E, Peretz T, Vlodavsky I (2004) Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. J Natl Cancer Inst 96:1219-1230.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1219-1230
-
-
Edovitsky, E.1
Elkin, M.2
Zcharia, E.3
Peretz, T.4
Vlodavsky, I.5
-
25
-
-
3042829493
-
Hypoxic stress tolerance of the blind subterranean mole rat: Expression of erythropoietin and hypoxia-inducible factor 1 α
-
Shams I, Avivi A, Nevo E (2004) Hypoxic stress tolerance of the blind subterranean mole rat: Expression of erythropoietin and hypoxia-inducible factor 1 α. Proc Natl Acad Sci USA 101:9698-9703.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9698-9703
-
-
Shams, I.1
Avivi, A.2
Nevo, E.3
-
26
-
-
5044222204
-
How did alternative splicing evolve?
-
Ast G (2004) How did alternative splicing evolve? Nat Rev Genet 5:773-782.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 773-782
-
-
Ast, G.1
-
27
-
-
0029874986
-
Bcl-x(S) anatagonizes the protective effects of Bcl-x(L)
-
Minn AJ, Boise LH, Thompson CB (1996) Bcl-x(S) anatagonizes the protective effects of Bcl-x(L). J Biol Chem 271:6306-6312.
-
(1996)
J Biol Chem
, vol.271
, pp. 6306-6312
-
-
Minn, A.J.1
Boise, L.H.2
Thompson, C.B.3
-
28
-
-
10344220521
-
Endogenous angiogenesis inhibitors
-
Folkman J (2004) Endogenous angiogenesis inhibitors. Apmis 112:496-507.
-
(2004)
Apmis
, vol.112
, pp. 496-507
-
-
Folkman, J.1
-
29
-
-
0033516398
-
Potential target found for antimetastasis drugs
-
Finkel E (1999) Potential target found for antimetastasis drugs. Science 285:33-34.
-
(1999)
Science
, vol.285
, pp. 33-34
-
-
Finkel, E.1
-
30
-
-
24144477955
-
Decreasing the metastatic potential in cancers: Targeting the heparan sulfate proteoglycans
-
Fjeldstad K, Kolset SO (2005) Decreasing the metastatic potential in cancers: Targeting the heparan sulfate proteoglycans. Curr Drug Targets 6:665-682.
-
(2005)
Curr Drug Targets
, vol.6
, pp. 665-682
-
-
Fjeldstad, K.1
Kolset, S.O.2
-
31
-
-
38149089538
-
A phase II study of the heparanase inhibitor PI-88 in patients with advanced melanoma
-
Lewis KD, et al. (2008) A phase II study of the heparanase inhibitor PI-88 in patients with advanced melanoma. Invest New Drugs 26:89-94.
-
(2008)
Invest New Drugs
, vol.26
, pp. 89-94
-
-
Lewis, K.D.1
-
32
-
-
34447287858
-
Heparanase: Structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate
-
Vlodavsky I, Ilan N, Naggi A, Casu B (2007) Heparanase: Structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfate. Curr Pharm Des 13:2057-2073.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 2057-2073
-
-
Vlodavsky, I.1
Ilan, N.2
Naggi, A.3
Casu, B.4
-
33
-
-
34548836012
-
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy
-
Yang Y, et al. (2007) The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy. Blood 110:2041-2048.
-
(2007)
Blood
, vol.110
, pp. 2041-2048
-
-
Yang, Y.1
|