Interaction of estrogen and tumor necrosis factor α in endothelial cell migration and early stage of angiogenesis

Endothelium: Journal of Endothelial Cell Research

Volumn 15, Issue 5-6, 2008, Pages 265-275

  Florian, Maria ^a   Florianova, Livia ^a   Hussain, Sabah ^a   Magder, Sheldon ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Angiogenesis; Cytokines; Endothelium; Estrogen; Nitric oxide

Indexed keywords

ANGIOPOIETIN 2; BROXURIDINE; ESTRADIOL; ESTROGEN; INTERLEUKIN 8; N(G) NITROARGININE METHYL ESTER; P21 ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN A; VASCULOTROPIN C; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA;

ANGIOGENESIS; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; GENE EXPRESSION; HORMONE ACTION; HORMONE INHIBITION; HUMAN; HUMAN CELL; HUMAN UMBILICAL ENDOTHELIAL CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WOUND HEALING; ATHEROSCLEROSIS; CELL MOTION; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; ESTROGEN THERAPY; FEMALE; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOPOIETIN-2; ATHEROSCLEROSIS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENDOTHELIAL CELLS; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; HUMANS; INTERLEUKIN-8; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR C; WOUND HEALING;

EID: 60549092391     PISSN: 10623329     EISSN: 10292373     Source Type: Journal    
DOI: 10.1080/10623320802487775     Document Type: Article

References (61)

1. Al Ghouleh, I. and Magder, S. (2008) Nicotinamide adenine dinucleotide phosphate (reduced form) oxidase is important for LPS-induced endothelial cell activation. Shock, 29, pp. 553-559.
2. Angerer, P., Stork, S., Kothny, W., Schmitt, P. and von Schacky, C. (2001) Effect of oral postmenopausal hormone replacement on progression of atherosclerosis: A randomized, controlled trial. Arteriosclerosis, Thrombosis, and Vascular Biology, 21, pp. 262-268.
3. Arenas, I. A., Armstrong, S. J., Xu, Y. and Davidge, S. T. (2005) Chronic tumor necrosis factor-alpha inhibition enhances NO modulation of vascular function in estrogen-deficient rats. Hypertension, 46, pp. 76-81.
4. Barrett-Connor, E. (1997) Sex differences in coronary heart disease. Why are women so superior? The 1995 Ancel Keys Lecture. Circulation, 95, pp. 252-264.
5. Berthois, Y., Katzenellenbogen, J. A. and Katzenellenbogen, B. S. (1986) Phenol red in tissue culture media is a weak estrogen Implications concerning the study of estrogen-responsive cells in culture. Proceedings of the National Academy of Sciences of the United States of America, 83, pp. 2496-2500.
6. Bokoch, G. M. (2003) Biology of the p21-activated kinases. Annual Review of Biochemistry, 72, pp. 743-781.
7. Brouchet, L., Krust, A., Dupont, S., Chambon, P., Bayard, F. and Arnal, J. F. (2001) Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation, 103, pp. 423-428.
8. Caulin-Glaser, T., Watson, C. A., Pardi, R. and Bender, J. R. (1996) Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression. The Journal of Clinical Investigation, 98, pp. 36-42.
9. Dantas, A. P. and Sandberg, K. (2005) Estrogen regulation of tumor necrosis factor-alpha: A missing link between menopause and cardiovascular risk in women?. Hypertension, 46, pp. 21-22.
10. Farhat, M. Y., Lavigne, M. C. and Ramwell, P. W. (1996) The vascular protective effects of estrogen. The FASEB Journal, 10, pp. 615-624.
11. Fletcher, S. W. and Colditz, G. A. (2002) Failure of estrogen plus progestin therapy for prevention. Journal of the American Medical Association, 288, pp. 366-368.
12. Florian, M., Lu, Y., Angle, M. and Magder, S. (2004) Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation. Steroids, 69, pp. 637-645.
13. Florian, M. and Magder, S. (2008) Estrogen decreases TNF-alpha and oxidized LDL induced apoptosis in endothelial cells. Steroids, 73, pp. 47-58.
14. Frater-Schroder, M., Risau, W., Hallmann, R., Gautschi, P. and Bohlen, P. (1987) Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo. Proceedings of the National Academy of Sciences of the United States of America, 84, pp. 5277-5281.
15. Gargett, C. E., Zaitseva, M., Bucak, K., Chu, S., Fuller, P. J. and Rogers, P. A. (2002) 17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: Role of estrogen receptor-alpha and -beta. The Journal of Clinical Endocrinology and Metabolism, 87, pp. 4341-4349.
16. Gerhard, M. and Ganz, P. (1995) How do we explain the clinical benefits of estrogen? From bedside to bench. Circulation, 92, pp. 5-8.
17. Gertzberg, N., Neumann, P., Rizzo, V. and Johnson, A. (2004) NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha. American Journal of Physiology, Lung, Cellular and Molecular Physiology, 286, pp. L37-L48.
18. Giraudo, E., Primo, L., Audero, E., Gerber, H. P., Koolwijk, P., Soker, S., Klagsbrun, M., Ferrara, N. and Bussolino, F. (1998) Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells. The Journal of Biological Chemistry, 273, pp. 22128-22135.
19. Grady, D., Rubin, S. M., Petitti, D. B., Fox, C. S., Black, D., Ettinger, B., Ernster, V. L. and Cummings, S. R. (1992) Hormone therapy to prevent disease and prolong life in postmenopausal women. Annals of internal medicine, 117, pp. 1016-1037.
20. Grainger, D. J. and Metcalfe, J. C. (1996) Tamoxifen: Teaching an old drug new tricks?. Nature Medicine, 2, pp. 381-385.
21. Grodstein, F., Stampfer, M. J., Colditz, G. A., Willett, W. C., Manson, J. E., Joffe, M., Rosner, B., Fuchs, C., Hankinson, S. E., Hunter, D. J., Hennekens, C. H. and Speizer, F. E. (1997) Postmenopausal hormone therapy and mortality. The New England journal of Medicine, 336, pp. 1769-1775.
22. Grodstein, F., Stampfer, M. J., Manson, J. E., Colditz, G. A., Willett, W. C., Rosner, B., Speizer, F. E. and Hennekens, C. H. (1996) Postmenopausal estrogen and progestin use and the risk of cardiovascular disease. The New England Journal of Medicine, 335, pp. 453-461.
23. Gruber, C. J., Tschugguel, W., Schneeberger, C. and Huber, J. C. (2002) Production and actions of estrogens. The New England Journal of Medicine, 346, pp. 340-352.
24. Hodgin, J. B., Krege, J. H., Reddick, R. L., Korach, K. S., Smithies, O. and Maeda, N. (2001) Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in ApoE-/- mice. The Journal of Clinical Investigation, 107, pp. 333-340.
25. Hulley, S., Grady, D., Bush, T., Furberg, C., Herrington, D., Riggs, B. and Vittinghoff, E. (1998) Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Journal of the American Medical Association, 280, pp. 605-613.
26. Karas, R. H. (2002) Animal models of the cardiovascular effects of exogenous hormones. The American Journal of Cardiology, 90, pp. 22F-25F.
27. Karas, R. H., Hodgin, J. B., Kwoun, M., Krege, J. H., Aronovitz, M. J., Mackey, W., Gustafsson, J. A., Korach, K. S., Smithies, O. and Mendelsohn, M. E. (1999) Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice. Proceedings of the National Academy of Sciences of the United States of America, 96, pp. 15133-15136.
28. Katzenellenbogen, J. A., Johnson Jr., H. J. and Myers, H. N. (1973) Photoaffinity labels for estrogen binding proteins of rat uterus. biochemistry, 12, pp. 4085-4092.
29. Klagsbrun, M. and D'Amore, P. A. (1991) Regulators of angiogenesis. Annual Review of Physiology, 53, pp. 217-239.
30. Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G. and Strieter, R. M. (1992) Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science, 258, pp. 1798-1801.
31. Krasinski, K., Spyridopoulos, I., Asahara, T., van der, Z. R., Isner, J. M. and Losordo, D. W. (1997) Estradiol accelerates functional endothelial recovery after arterial injury. Circulation, 95, pp. 1768-1772.
32. Lau, Y. T. and Ma, W. C. (1996) Nitric oxide inhibits migration of cultured endothelial cells. Biochemical and Biophysical Research Communications, 221, pp. 670-674.
33. Leibovich, S. J., Polverini, P. J., Shepard, H. M., Wiseman, D. M., Shively, V. and Nuseir, N. (1987) Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha. Nature, 329, pp. 630-632.
34. Levin, E. R. (2002) Estrogen receptor-beta and the cardiovascular system. Trends in Endocrinology and Metabolism, 13, pp. 184-185.
35. Losordo, D. W. and Isner, J. M. (2001) Estrogen and angiogenesis, A review. Arteriosclerosis, Thrombosis, and Vascular Biology, 21, pp. 6-12.
36. Mazumdar, A. and Kumar, R. (2003) Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells. FEBS Letters, 535, pp. 6-10.
37. Mendelsohn, M. E. (2000) Nongenomic, ER-mediated activation of endothelial nitric oxide synthase: How does it work? What does it mean?. Circulation Research, 87, pp. 956-960.
38. Mendelsohn, M. E. (2002) Protective effects of estrogen on the cardiovascular system. The American Journal of Cardiology, 89, pp. 12E-17E.
39. Mendelsohn, M. E. and Karas, R. H. (1994) Estrogen and the blood vessel wall. Current Opinion in Cardiology, 9, pp. 619-626.
40. Mendelsohn, M. E. and Karas, R. H. (1999) The protective effects of estrogen on the cardiovascular system. The New England Journal of Medicine, 340, pp. 1801-1811.
41. Mikkola, T. S. and Clarkson, T. B. (2002) Estrogen replacement therapy, atherosclerosis, and vascular function. Cardiovascular Research, 53, pp. 605-619.
42. Morales, D. E., McGowan, K. A., Grant, D. S., Maheshwari, S., Bhartiya, D., Cid, M. C., Kleinman, H. K. and Schnaper, H. W. (1995) Estrogen promotes angiogenic activity in human umbilical vein endothelial cells in vitro and in a murine model. Circulation, 91, pp. 755-763.
43. Mosca, L., Manson, J. E., Sutherland, S. E., Langer, R. D., Manolio, T. and Barrett-Connor, E. (1997) Cardiovascular disease in women: A statement for healthcare professionals from the American Heart Association. Writing Group. Circulation, 96, pp. 2468-2482.
44. Murohara, T., Asahara, T., Silver, M., Bauters, C., Masuda, H., Kalka, C., Kearney, M., Chen, D., Symes, J. F., Fishman, M. C., Huang, P. L. and Isner, J. M. (1998) Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. The Journal of Clinical Investigation, 101, pp. 2567-2578.
45. Papapetropoulos, A., Garcia-Cardena, G., Madri, J. A. and Sessa, W. C. (1997) Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. The Journal of Clinical Investigation, pp. 3131-3139.
46. Pare, G., Krust, A., Karas, R. H., Dupont, S., Aronovitz, M., Chambon, P. and Mendelsohn, M. E. (2002) Estrogen receptor-alpha mediates the protective effects of estrogen against vascular injury. Circulation Research, 90, pp. 1087-1092.
47. Peters, K. G., Kontos, C. D., Lin, P. C., Wong, A. L., Rao, P., Huang, L., Dewhirst, M. W. and Sankar, S. (2004) Functional significance of Tie2 signaling in the adult vasculature. Recent Progress in Hormone Research, 59, pp. 51-71.
48. Petitti, D. B. (1998) Hormone replacement therapy and heart disease prevention: Experimentation trumps observation. Journal of the American Medical Association, 280, pp. 650-652.
49. Pipili-Synetos, E., Sakkoula, E., Haralabopoulos, G., Andriopoulou, P., Peristeris, P. and Maragoudakis, M. E. (1994) Evidence that nitric oxide is an endogenous antiangiogenic mediator. British Journal of Pharmacology, 111, pp. 894-902.
50. Razandi, M., Pedram, A. and Levin, E. R. (2000) Estrogen signals to the preservation of endothelial cell form and function. The Journal of Biological Chemistry, 275, pp. 38540-38546.
51. Ross, R. (1993) The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature, 362, pp. 801-809.
52. Rossouw, J. E. (2002) Hormones, genetic factors, and gender differences in cardiovascular disease. Cardiovascular Research, 53, pp. 550-557.
53. Rossouw, J. E., Anderson, G. L., Prentice, R. L., LaCroix, A. Z., Kooperberg, C., Stefanick, M. L., Jackson, R. D., Beresford, S. A., Howard, B. V., Johnson, K. C., Kotchen, J. M., Ockene, J. and Writing Group for the Women's Health Initiative Investigators (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results From the Women's Health Initiative randomized controlled trial. Journal of the American Medical Association, pp. 321-333.
54. Ruohola, J. K., Valve, E. M., Karkkainen, M. J., Joukov, V., Alitalo, K. and Harkonen, P. L. (1999) Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells. Molecular and Cellular Endocrinology, 149, pp. 29-40.
55. Schulman, S. P., Thiemann, D. R., Ouyang, P., Chandra, N. C., Schulman, D. S., Reis, S. E., Terrin, M., Forman, S., de Albuquerque, C. P., Bahr, R. D., Townsend, S. N., Cosgriff, R. and Gerstenblith, G. (2002) Effects of acute hormone therapy on recurrent ischemia in postmenopausal women with unstable angina. Journal of the American College of Cardiology, 39, pp. 231-237.
56. Sotelo, M. M. and Johnson, S. R. (1997) The effects of hormone replacement therapy on coronary heart disease. Endocrinology and Metabolism Clinics of North America, 26, pp. 313-328.
57. Spyridopoulos, I., Sullivan, A. B., Kearney, M., Isner, J. M. and Losordo, D. W. (1997) Estrogen-receptor-mediated inhibition of human endothelial cell apoptosis. Estradiol as a survival factor. Circulation, 95, pp. 1505-1514.
58. Viscoli, C. M., Brass, L. M., Kernan, W. N., Sarrel, P. M., Suissa, S. and Horwitz, R. I. (2001) A clinical trial of estrogen-replacement therapy after ischemic stroke. The New England Journal of Medicine, 345, pp. 1243-1249.
59. Williams, J. K., Honore, E. K., Washburn, S. A. and Clarkson, T. B. (1994) Effects of hormone replacement therapy on reactivity of atherosclerotic coronary arteries in cynomolgus monkeys. Journal of the American College of Cardiology, 24, pp. 1757-1761.
60. Xu, Y., Arenas, I. A., Armstrong, S. J., Plahta, W. C., Xu, H. and Davidge, S. T. (2006) Estrogen improves cardiac recovery after ischemia/ reperfusion by decreasing tumor necrosis factor-alpha. Cardiovascular Research, 69, pp. 836-844.
61. Ye, F., Florian, M., Magder, S. and Hussain, S. (2002) Regulation of angiopoietin and Tie-2 receptor expression in non-reproductive tissues by estrogen. Steroids, 67, pp. 305-310.